DK125244B - Fremgangsmåde til fremstilling af 9α-fluor-16-methyl-prednisolon eller -prednison eller 21-estere deraf. - Google Patents
Fremgangsmåde til fremstilling af 9α-fluor-16-methyl-prednisolon eller -prednison eller 21-estere deraf.Info
- Publication number
- DK125244B DK125244B DK314269AA DK314269A DK125244B DK 125244 B DK125244 B DK 125244B DK 314269A A DK314269A A DK 314269AA DK 314269 A DK314269 A DK 314269A DK 125244 B DK125244 B DK 125244B
- Authority
- DK
- Denmark
- Prior art keywords
- prednisolone
- prednisone
- fluoro
- esters
- methyl
- Prior art date
Links
- 229960001810 meprednisone Drugs 0.000 title 1
- XOFYZVNMUHMLCC-ZPOLXVRWSA-N prednisone Chemical compound O=C1C=C[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 XOFYZVNMUHMLCC-ZPOLXVRWSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19681793318 DE1793318C3 (de) | 1968-08-31 | Verfahren zur Herstellung von 9 a-Fluor-16methylen-prednisolon bzw. -prednison und 21-Estern derselben |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK125244B true DK125244B (da) | 1973-01-22 |
Family
ID=5707659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK314269AA DK125244B (da) | 1968-08-31 | 1969-06-11 | Fremgangsmåde til fremstilling af 9α-fluor-16-methyl-prednisolon eller -prednison eller 21-estere deraf. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3684800A (da) |
| AT (1) | AT310956B (da) |
| BE (1) | BE738086A (da) |
| BR (1) | BR6910529D0 (da) |
| CH (1) | CH521333A (da) |
| CS (1) | CS172308B2 (da) |
| DK (1) | DK125244B (da) |
| ES (1) | ES371022A1 (da) |
| FR (1) | FR2016708A1 (da) |
| GB (1) | GB1213118A (da) |
| IL (1) | IL32378A (da) |
| NL (1) | NL6908358A (da) |
| SE (1) | SE351846B (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4207235A (en) * | 1979-01-12 | 1980-06-10 | Syntex (U.S.A.) Inc. | Selective epoxidation of steroidal bromohydrins |
| CN101125877B (zh) * | 2007-09-10 | 2011-04-06 | 浙江仙琚制药股份有限公司 | 甲基泼尼松龙醋酸酯的制备方法 |
| CN102061320B (zh) * | 2010-12-02 | 2013-04-03 | 浙江仙琚制药股份有限公司 | 11α，17α-二羟基-雄甾-4-烯-3，20-二酮的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3321496A (en) * | 1960-11-17 | 1967-05-23 | Merck & Co Inc | 16alpha-halo methyl-saturated steroids of the pregnane series |
| US3376294A (en) * | 1961-04-26 | 1968-04-02 | Pfizer & Co C | 6-fluoro-16-methylene steroid compounds and process |
| DE1251758B (de) * | 1965-03-23 | 1967-10-12 | E Merck Aktiengesellschaft, Darmstadt | Verfahien zur Herstellung von 6a, 9a-Difluor- 16 methylen 1 4 pregnadien 11/?, 17a d'ol 3 20 dion |
-
1969
- 1969-05-07 CS CS3236A patent/CS172308B2/cs unknown
- 1969-05-12 CH CH726969A patent/CH521333A/de not_active IP Right Cessation
- 1969-06-02 NL NL6908358A patent/NL6908358A/xx unknown
- 1969-06-04 GB GB28344/69A patent/GB1213118A/en not_active Expired
- 1969-06-09 AT AT545969A patent/AT310956B/de not_active IP Right Cessation
- 1969-06-11 IL IL32378A patent/IL32378A/en unknown
- 1969-06-11 DK DK314269AA patent/DK125244B/da unknown
- 1969-07-08 BR BR210529/69A patent/BR6910529D0/pt unknown
- 1969-07-18 FR FR6924528A patent/FR2016708A1/fr not_active Withdrawn
- 1969-08-16 SE SE10056/69A patent/SE351846B/xx unknown
- 1969-08-21 US US847578A patent/US3684800A/en not_active Expired - Lifetime
- 1969-08-28 BE BE738086D patent/BE738086A/xx unknown
- 1969-08-30 ES ES371022A patent/ES371022A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| SE351846B (da) | 1972-12-11 |
| IL32378A (en) | 1972-10-29 |
| FR2016708A1 (da) | 1970-05-08 |
| CH521333A (de) | 1972-04-15 |
| CS172308B2 (da) | 1976-12-29 |
| NL6908358A (da) | 1970-03-03 |
| DE1793318A1 (de) | 1972-03-02 |
| GB1213118A (en) | 1970-11-18 |
| AT310956B (de) | 1973-10-25 |
| BE738086A (da) | 1970-03-02 |
| IL32378A0 (en) | 1969-08-27 |
| DE1793318B2 (de) | 1976-12-30 |
| US3684800A (en) | 1972-08-15 |
| ES371022A1 (es) | 1971-12-16 |
| BR6910529D0 (pt) | 1973-03-13 |
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