IL318981A - Method for preparing crystalline forms of 1,2,4-oxadiazole-3-methyl-1,2-dione - Google Patents

Method for preparing crystalline forms of 1,2,4-oxadiazole-3-methyl-1,2-dione

Info

Publication number
IL318981A
IL318981A IL318981A IL31898125A IL318981A IL 318981 A IL318981 A IL 318981A IL 318981 A IL318981 A IL 318981A IL 31898125 A IL31898125 A IL 31898125A IL 318981 A IL318981 A IL 318981A
Authority
IL
Israel
Prior art keywords
compound
formula
solution
solvent
mixture
Prior art date
Application number
IL318981A
Other languages
English (en)
Hebrew (he)
Original Assignee
Aurigene Oncology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aurigene Oncology Ltd filed Critical Aurigene Oncology Ltd
Publication of IL318981A publication Critical patent/IL318981A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL318981A 2017-10-11 2018-10-10 Method for preparing crystalline forms of 1,2,4-oxadiazole-3-methyl-1,2-dione IL318981A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN201741036169 2017-10-11
PCT/IB2018/057840 WO2019073399A1 (en) 2017-10-11 2018-10-10 CRYSTALLINE FORMS OF 1,2,4-OXADIAZOLE SUBSTITUTED IN POSITION 3

Publications (1)

Publication Number Publication Date
IL318981A true IL318981A (en) 2025-04-01

Family

ID=64664328

Family Applications (2)

Application Number Title Priority Date Filing Date
IL318981A IL318981A (en) 2017-10-11 2018-10-10 Method for preparing crystalline forms of 1,2,4-oxadiazole-3-methyl-1,2-dione
IL273896A IL273896B2 (en) 2017-10-11 2018-10-10 Crystalline forms of 3-substituted 1,2,4-oxadiazole

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL273896A IL273896B2 (en) 2017-10-11 2018-10-10 Crystalline forms of 3-substituted 1,2,4-oxadiazole

Country Status (14)

Country Link
US (4) US11136300B2 (https=)
EP (1) EP3694841A1 (https=)
JP (2) JP7618445B2 (https=)
KR (2) KR20240151258A (https=)
CN (2) CN111194308A (https=)
AU (2) AU2018348350B2 (https=)
BR (1) BR112020006669A2 (https=)
CA (1) CA3078872A1 (https=)
EA (1) EA202090536A1 (https=)
IL (2) IL318981A (https=)
MY (1) MY201777A (https=)
PH (1) PH12020550125A1 (https=)
SG (1) SG11202003081WA (https=)
WO (1) WO2019073399A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
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WO2019061324A1 (en) 2017-09-29 2019-04-04 Curis Inc. CRYSTALLINE FORMS OF IMMUNOMODULATORS
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MY206121A (en) 2017-11-03 2024-11-29 Aurigene Discovery Tech Ltd Dual inhibitors of tim-3 and pd-1 pathways
AU2018360389B2 (en) 2017-11-06 2024-09-19 Aurigene Oncology Limited Conjoint therapies for immunomodulation

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MY206121A (en) 2017-11-03 2024-11-29 Aurigene Discovery Tech Ltd Dual inhibitors of tim-3 and pd-1 pathways
AU2018360389B2 (en) 2017-11-06 2024-09-19 Aurigene Oncology Limited Conjoint therapies for immunomodulation

Also Published As

Publication number Publication date
US11136300B2 (en) 2021-10-05
KR20240151258A (ko) 2024-10-17
IL273896A (en) 2020-05-31
PH12020550125A1 (en) 2021-01-25
EA202090536A1 (ru) 2020-07-22
AU2018348350A1 (en) 2020-04-02
JP7618445B2 (ja) 2025-01-21
US20250136562A1 (en) 2025-05-01
CA3078872A1 (en) 2019-04-18
AU2018348350B2 (en) 2024-05-02
CN117417308A (zh) 2024-01-19
JP2023109937A (ja) 2023-08-08
KR20200068659A (ko) 2020-06-15
CN111194308A (zh) 2020-05-22
SG11202003081WA (en) 2020-05-28
US20220048875A1 (en) 2022-02-17
US20200239422A1 (en) 2020-07-30
KR102838640B1 (ko) 2025-07-24
AU2024202522A1 (en) 2024-05-09
IL273896B2 (en) 2025-08-01
IL273896B1 (en) 2025-04-01
EP3694841A1 (en) 2020-08-19
US20230278970A1 (en) 2023-09-07
US11680051B2 (en) 2023-06-20
WO2019073399A1 (en) 2019-04-18
MY201777A (en) 2024-03-17
US12187689B2 (en) 2025-01-07
JP2020536872A (ja) 2020-12-17
BR112020006669A2 (pt) 2020-09-24

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