KR20240151258A - 3-치환된 1,2,4-옥사다이아졸의 결정질 형태 - Google Patents

3-치환된 1,2,4-옥사다이아졸의 결정질 형태 Download PDF

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Publication number
KR20240151258A
KR20240151258A KR1020247032835A KR20247032835A KR20240151258A KR 20240151258 A KR20240151258 A KR 20240151258A KR 1020247032835 A KR1020247032835 A KR 1020247032835A KR 20247032835 A KR20247032835 A KR 20247032835A KR 20240151258 A KR20240151258 A KR 20240151258A
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compound
crystalline compound
formula
producing
crystalline
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Ceased
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Korean (ko)
Inventor
포타열 고빈단 나이르 사시쿠마
시싸라마야 세티 수다르샨 나레마데팔리
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오리진 온콜로지 리미티드
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Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
KR1020247032835A 2017-10-11 2018-10-10 3-치환된 1,2,4-옥사다이아졸의 결정질 형태 Ceased KR20240151258A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN201741036169 2017-10-11
IN201741036169 2017-10-11
PCT/IB2018/057840 WO2019073399A1 (en) 2017-10-11 2018-10-10 CRYSTALLINE FORMS OF 1,2,4-OXADIAZOLE SUBSTITUTED IN POSITION 3
KR1020207009846A KR102838640B1 (ko) 2017-10-11 2018-10-10 3-치환된 1,2,4-옥사다이아졸의 결정질 형태

Related Parent Applications (1)

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KR1020207009846A Division KR102838640B1 (ko) 2017-10-11 2018-10-10 3-치환된 1,2,4-옥사다이아졸의 결정질 형태

Publications (1)

Publication Number Publication Date
KR20240151258A true KR20240151258A (ko) 2024-10-17

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KR1020247032835A Ceased KR20240151258A (ko) 2017-10-11 2018-10-10 3-치환된 1,2,4-옥사다이아졸의 결정질 형태
KR1020207009846A Active KR102838640B1 (ko) 2017-10-11 2018-10-10 3-치환된 1,2,4-옥사다이아졸의 결정질 형태

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Country Status (14)

Country Link
US (4) US11136300B2 (https=)
EP (1) EP3694841A1 (https=)
JP (2) JP7618445B2 (https=)
KR (2) KR20240151258A (https=)
CN (2) CN117417308A (https=)
AU (2) AU2018348350B2 (https=)
BR (1) BR112020006669A2 (https=)
CA (1) CA3078872A1 (https=)
EA (1) EA202090536A1 (https=)
IL (2) IL273896B2 (https=)
MY (1) MY201777A (https=)
PH (1) PH12020550125A1 (https=)
SG (1) SG11202003081WA (https=)
WO (1) WO2019073399A1 (https=)

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* Cited by examiner, † Cited by third party
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CN111386128A (zh) 2017-11-06 2020-07-07 奥瑞基尼探索技术有限公司 用于免疫调节的联合疗法

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Also Published As

Publication number Publication date
US20250136562A1 (en) 2025-05-01
JP2020536872A (ja) 2020-12-17
US11136300B2 (en) 2021-10-05
CA3078872A1 (en) 2019-04-18
SG11202003081WA (en) 2020-05-28
PH12020550125A1 (en) 2021-01-25
CN117417308A (zh) 2024-01-19
IL273896B2 (en) 2025-08-01
US20200239422A1 (en) 2020-07-30
AU2018348350A1 (en) 2020-04-02
WO2019073399A1 (en) 2019-04-18
EP3694841A1 (en) 2020-08-19
AU2018348350B2 (en) 2024-05-02
US11680051B2 (en) 2023-06-20
EA202090536A1 (ru) 2020-07-22
IL273896A (en) 2020-05-31
BR112020006669A2 (pt) 2020-09-24
JP7618445B2 (ja) 2025-01-21
US20230278970A1 (en) 2023-09-07
MY201777A (en) 2024-03-17
US12187689B2 (en) 2025-01-07
IL318981A (en) 2025-04-01
JP2023109937A (ja) 2023-08-08
AU2024202522A1 (en) 2024-05-09
IL273896B1 (en) 2025-04-01
US20220048875A1 (en) 2022-02-17
CN111194308A (zh) 2020-05-22
KR20200068659A (ko) 2020-06-15
KR102838640B1 (ko) 2025-07-24

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