IL305541A - Extended release formulations for intra-articular applications - Google Patents
Extended release formulations for intra-articular applicationsInfo
- Publication number
- IL305541A IL305541A IL305541A IL30554123A IL305541A IL 305541 A IL305541 A IL 305541A IL 305541 A IL305541 A IL 305541A IL 30554123 A IL30554123 A IL 30554123A IL 305541 A IL305541 A IL 305541A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical composition
- optionally
- water
- oxabicyclo
- dichlorophenyl
- Prior art date
Links
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4465—Non condensed piperidines, e.g. piperocaine only substituted in position 4
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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- A—HUMAN NECESSITIES
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
Landscapes
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Orthopedic Medicine & Surgery (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
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- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US201762584589P | 2017-11-10 | 2017-11-10 | |
| US201862743864P | 2018-10-10 | 2018-10-10 | |
| PCT/IB2018/058788 WO2019092637A1 (en) | 2017-11-10 | 2018-11-08 | Extended release formulations for intra-articular applications |
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| IL305541A true IL305541A (en) | 2023-10-01 |
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| IL305541A IL305541A (en) | 2017-11-10 | 2018-11-08 | Extended release formulations for intra-articular applications |
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| Application Number | Title | Priority Date | Filing Date |
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| IL274149A IL274149B2 (en) | 2017-11-10 | 2018-11-08 | Sustained release formulations for intra-articular applications |
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| EP (1) | EP3706710B1 (enExample) |
| JP (1) | JP7284750B2 (enExample) |
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| HU (1) | HUE066971T2 (enExample) |
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| TW (2) | TWI813597B (enExample) |
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| EP3891154B1 (en) * | 2018-12-06 | 2023-08-16 | Novartis AG | 5-hydroxy-7-oxabicyclo[2.2.1]heptane-2-carboxamide derivatives for inducing chondrogenesis for treating joint damage |
| KR20220076371A (ko) * | 2020-11-30 | 2022-06-08 | 주식회사 엘지화학 | 캐스파제 저해제를 함유하는 주사용 조성물 및 이의 제조 방법 |
| KR20240133027A (ko) | 2023-02-28 | 2024-09-04 | 주식회사 포스테라헬스사이언스 | 올리고펩타이드를 포함하는 서방형 입자 및 이의 제조 방법 |
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| CA2947031C (en) * | 2014-05-13 | 2023-01-24 | Novartis Ag | Compounds and compositions for inducing chondrogenesis |
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2018
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- 2018-11-08 TW TW112133215A patent/TW202400164A/zh unknown
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