IL303816A - Antibodies specific for structurally disordered sequences - Google Patents
Antibodies specific for structurally disordered sequencesInfo
- Publication number
- IL303816A IL303816A IL303816A IL30381623A IL303816A IL 303816 A IL303816 A IL 303816A IL 303816 A IL303816 A IL 303816A IL 30381623 A IL30381623 A IL 30381623A IL 303816 A IL303816 A IL 303816A
- Authority
- IL
- Israel
- Prior art keywords
- mab
- seq
- antigen
- cdr
- antibody
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57581—Thymosin; Related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/35—Valency
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20216744 | 2020-12-22 | ||
| PCT/EP2021/087365 WO2022136582A1 (en) | 2020-12-22 | 2021-12-22 | Antibodies specific for structurally disordered sequences |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL303816A true IL303816A (en) | 2023-08-01 |
Family
ID=73856935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL303816A IL303816A (en) | 2020-12-22 | 2021-12-22 | Antibodies specific for structurally disordered sequences |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20240294632A1 (https=) |
| EP (1) | EP4267628A1 (https=) |
| JP (1) | JP2024501316A (https=) |
| KR (1) | KR20230124637A (https=) |
| CN (1) | CN117120476A (https=) |
| AU (1) | AU2021405029A1 (https=) |
| CA (1) | CA3200238A1 (https=) |
| IL (1) | IL303816A (https=) |
| WO (1) | WO2022136582A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118146384A (zh) * | 2020-09-28 | 2024-06-07 | 安济盛生物医药有限公司 | 抗硬骨抑素构建体及其用途 |
| EP4602053A2 (en) * | 2022-10-14 | 2025-08-20 | Aikium Inc. | Protein scaffolds for disordered regions |
| WO2025088192A1 (en) * | 2023-10-27 | 2025-05-01 | Xl-Protein Gmbh | Methods for the coupling of di(alkyl)amines to polypeptides |
| CN117683866B (zh) * | 2024-01-22 | 2024-08-06 | 湛江中心人民医院 | 检测细胞中dna的方法 |
| CN118290585B (zh) * | 2024-06-04 | 2024-08-30 | 苏州为度生物技术有限公司天津分公司 | 一种抗人cd14工程抗体及应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2173890T1 (sl) | 2007-06-21 | 2011-06-30 | Univ Muenchen Tech | Biološko aktivni proteini, ki imajo povečano in vivo in/ali in vitro stabilnost |
| US9221882B2 (en) | 2010-05-21 | 2015-12-29 | Technische Universitat Munchen | Biosynthetic proline/alanine random coil polypeptides and their uses |
| WO2017109087A1 (en) | 2015-12-22 | 2017-06-29 | Xl-Protein Gmbh | Nucleic acids encoding repetitive amino acid sequences rich in proline and alanine residues that have low repetitive nucleotide sequences |
| GB201600176D0 (en) * | 2016-01-06 | 2016-02-17 | Cambridge Entpr Ltd | Method of identifying novel protein aggregation inhibitors based on chemical kinetics |
| CN110891612A (zh) | 2017-06-21 | 2020-03-17 | Xl-蛋白有限责任公司 | 蛋白质药物与p/a肽的缀合物 |
-
2021
- 2021-12-22 KR KR1020237024420A patent/KR20230124637A/ko active Pending
- 2021-12-22 IL IL303816A patent/IL303816A/en unknown
- 2021-12-22 CA CA3200238A patent/CA3200238A1/en active Pending
- 2021-12-22 AU AU2021405029A patent/AU2021405029A1/en active Pending
- 2021-12-22 WO PCT/EP2021/087365 patent/WO2022136582A1/en not_active Ceased
- 2021-12-22 JP JP2023539757A patent/JP2024501316A/ja active Pending
- 2021-12-22 US US18/268,880 patent/US20240294632A1/en active Pending
- 2021-12-22 CN CN202180087405.1A patent/CN117120476A/zh active Pending
- 2021-12-22 EP EP21844315.8A patent/EP4267628A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2022136582A1 (en) | 2022-06-30 |
| JP2024501316A (ja) | 2024-01-11 |
| EP4267628A1 (en) | 2023-11-01 |
| AU2021405029A9 (en) | 2025-03-13 |
| AU2021405029A1 (en) | 2023-07-20 |
| KR20230124637A (ko) | 2023-08-25 |
| US20240294632A1 (en) | 2024-09-05 |
| CA3200238A1 (en) | 2022-06-30 |
| CN117120476A (zh) | 2023-11-24 |
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