IL301857A - Transgenic enzymes of phosphopantomutase variants - Google Patents

Transgenic enzymes of phosphopantomutase variants

Info

Publication number
IL301857A
IL301857A IL301857A IL30185723A IL301857A IL 301857 A IL301857 A IL 301857A IL 301857 A IL301857 A IL 301857A IL 30185723 A IL30185723 A IL 30185723A IL 301857 A IL301857 A IL 301857A
Authority
IL
Israel
Prior art keywords
thc
seq
sequence
engineered phosphopentomutase
phosphopentomutase
Prior art date
Application number
IL301857A
Other languages
English (en)
Hebrew (he)
Inventor
Jonathan Vroom
Santhosh Sivaramakrishnan
Jessica Anna Hurtak
Original Assignee
Codexis Inc
Jonathan Vroom
Santhosh Sivaramakrishnan
Jessica Anna Hurtak
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Codexis Inc, Jonathan Vroom, Santhosh Sivaramakrishnan, Jessica Anna Hurtak filed Critical Codexis Inc
Publication of IL301857A publication Critical patent/IL301857A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y504/00—Intramolecular transferases (5.4)
    • C12Y504/02—Phosphotransferases (phosphomutases) (5.4.2)
    • C12Y504/02007—Phosphopentomutase (5.4.2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Ecology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL301857A 2020-10-07 2021-10-05 Transgenic enzymes of phosphopantomutase variants IL301857A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063088556P 2020-10-07 2020-10-07
PCT/US2021/053626 WO2022076454A1 (en) 2020-10-07 2021-10-05 Engineered phosphopentomutase variant enzymes

Publications (1)

Publication Number Publication Date
IL301857A true IL301857A (en) 2023-06-01

Family

ID=81125465

Family Applications (1)

Application Number Title Priority Date Filing Date
IL301857A IL301857A (en) 2020-10-07 2021-10-05 Transgenic enzymes of phosphopantomutase variants

Country Status (8)

Country Link
US (1) US12668789B2 (enExample)
EP (1) EP4225909A4 (enExample)
JP (1) JP2023544783A (enExample)
CN (1) CN116710558A (enExample)
AU (1) AU2021358938A1 (enExample)
CA (1) CA3196715A1 (enExample)
IL (1) IL301857A (enExample)
WO (1) WO2022076454A1 (enExample)

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Also Published As

Publication number Publication date
EP4225909A4 (en) 2025-02-12
US12668789B2 (en) 2026-06-30
EP4225909A1 (en) 2023-08-16
US20230374486A1 (en) 2023-11-23
CA3196715A1 (en) 2022-04-14
CN116710558A (zh) 2023-09-05
AU2021358938A1 (en) 2023-04-27
WO2022076454A1 (en) 2022-04-14
JP2023544783A (ja) 2023-10-25

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