IL298134A - Methods and kits for the detection of adeno-associated viruses - Google Patents

Methods and kits for the detection of adeno-associated viruses

Info

Publication number
IL298134A
IL298134A IL298134A IL29813422A IL298134A IL 298134 A IL298134 A IL 298134A IL 298134 A IL298134 A IL 298134A IL 29813422 A IL29813422 A IL 29813422A IL 298134 A IL298134 A IL 298134A
Authority
IL
Israel
Prior art keywords
aav
binds
kit
capture reagent
reagent
Prior art date
Application number
IL298134A
Other languages
English (en)
Hebrew (he)
Inventor
Peng Wang
Bingnan Gu
Anandita Seth
Original Assignee
Lonza Houston Inc
Peng Wang
Bingnan Gu
Anandita Seth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Houston Inc, Peng Wang, Bingnan Gu, Anandita Seth filed Critical Lonza Houston Inc
Publication of IL298134A publication Critical patent/IL298134A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/075—Adenoviridae
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
IL298134A 2020-05-12 2021-05-10 Methods and kits for the detection of adeno-associated viruses IL298134A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063023629P 2020-05-12 2020-05-12
PCT/US2021/031577 WO2021231296A1 (en) 2020-05-12 2021-05-10 Methods and kits for detecting adeno-associated viruses

Publications (1)

Publication Number Publication Date
IL298134A true IL298134A (en) 2023-01-01

Family

ID=76483343

Family Applications (1)

Application Number Title Priority Date Filing Date
IL298134A IL298134A (en) 2020-05-12 2021-05-10 Methods and kits for the detection of adeno-associated viruses

Country Status (8)

Country Link
US (1) US20230168250A1 (https=)
EP (2) EP4143577B1 (https=)
JP (1) JP7763771B2 (https=)
KR (1) KR20230009377A (https=)
CN (1) CN115335704A (https=)
CA (1) CA3172980A1 (https=)
IL (1) IL298134A (https=)
WO (1) WO2021231296A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4363597A1 (en) * 2022-01-20 2024-05-08 Sartorius Xell GmbH Method for the detection and quantification of adeno-associated viruses (aavs) using an affinity matrix
CN119452254A (zh) * 2022-04-18 2025-02-14 万迈医疗仪器有限公司 用于确定dna病毒中的dna浓度的方法
EP4705768A1 (en) * 2023-05-05 2026-03-11 Regeneron Pharmaceuticals, Inc. Labeling and anti-drug antibody assays for aav vectors

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4954796A (en) * 1995-03-17 1996-10-08 Hisamitsu Pharmaceutical Co., Inc. Monoclonal antibody specifically recognizing adeno-associated virus cap protein
US7419817B2 (en) * 2002-05-17 2008-09-02 The United States Of America As Represented By The Secretary Department Of Health And Human Services, Nih. Scalable purification of AAV2, AAV4 or AAV5 using ion-exchange chromatography
EP1724359A1 (en) * 2005-05-18 2006-11-22 PerkinElmer Life and Analytical Sciences B.V. Luciferase assay system
SG169395A1 (en) * 2006-02-09 2011-03-30 Univ South Florida Detection of cancer by elevated levels of bcl-2
WO2016035197A1 (ja) * 2014-09-05 2016-03-10 株式会社日立製作所 電気化学免疫センサ用カートリッジ及びそれを用いた測定装置
CN108603235A (zh) * 2015-07-30 2018-09-28 马萨诸塞眼科耳科诊所 祖先病毒序列及其用途
JP7467119B2 (ja) 2017-02-17 2024-04-15 ロンザ リミテッド 発現困難タンパク質のための多部位ｓｓｉ細胞
WO2018170015A1 (en) * 2017-03-14 2018-09-20 The Regents Of The University Of California Engineering crispr cas9 immune stealth
US20200231986A1 (en) * 2017-09-29 2020-07-23 Massachusetts Eye And Ear Infirmary Production of adeno-associated viruses in insect cells
WO2019212922A1 (en) * 2018-04-29 2019-11-07 Regenxbio Inc. Systems and methods of spectrophotometry for the determination of genome content, capsid content and full/empty ratios of adeno-associated virus particles
WO2021067874A1 (en) * 2019-10-02 2021-04-08 Oregon Health & Science University Production of anti-viral monoclonal antibodies by hydrodynamic-based transfection

Also Published As

Publication number Publication date
CA3172980A1 (en) 2021-11-18
EP4143577B1 (en) 2025-12-10
EP4692800A3 (en) 2026-04-22
JP2023525204A (ja) 2023-06-15
EP4692800A2 (en) 2026-02-11
US20230168250A1 (en) 2023-06-01
KR20230009377A (ko) 2023-01-17
JP7763771B2 (ja) 2025-11-04
WO2021231296A1 (en) 2021-11-18
EP4143577A1 (en) 2023-03-08
CN115335704A (zh) 2022-11-11

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