IL29750A - 1-phenyl-2,3-dimethyl-4-(2-bicyclo(2.2.1)heptyl)-amino-3-pyrazolin-5-one and process for its preparation - Google Patents
1-phenyl-2,3-dimethyl-4-(2-bicyclo(2.2.1)heptyl)-amino-3-pyrazolin-5-one and process for its preparationInfo
- Publication number
- IL29750A IL29750A IL29750A IL2975068A IL29750A IL 29750 A IL29750 A IL 29750A IL 29750 A IL29750 A IL 29750A IL 2975068 A IL2975068 A IL 2975068A IL 29750 A IL29750 A IL 29750A
- Authority
- IL
- Israel
- Prior art keywords
- bicyclo
- reductive
- pyrazolin
- heptyl
- dimethyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 5
- 238000002360 preparation method Methods 0.000 title description 2
- 230000002829 reductive effect Effects 0.000 claims description 9
- 238000009833 condensation Methods 0.000 claims description 7
- 230000005494 condensation Effects 0.000 claims description 7
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims description 4
- 150000003839 salts Chemical class 0.000 claims description 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 2
- 229910052739 hydrogen Inorganic materials 0.000 claims description 2
- 239000001257 hydrogen Substances 0.000 claims description 2
- 238000005984 hydrogenation reaction Methods 0.000 claims description 2
- 229910052759 nickel Inorganic materials 0.000 claims description 2
- 239000003054 catalyst Substances 0.000 claims 1
- 229910017052 cobalt Inorganic materials 0.000 claims 1
- 239000010941 cobalt Substances 0.000 claims 1
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 description 8
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- ZPVFWPFBNIEHGJ-UHFFFAOYSA-N 2-octanone Chemical compound CCCCCCC(C)=O ZPVFWPFBNIEHGJ-UHFFFAOYSA-N 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 229910052796 boron Inorganic materials 0.000 description 1
- XLKNMWIXNFVJRR-UHFFFAOYSA-N boron potassium Chemical compound [B].[K] XLKNMWIXNFVJRR-UHFFFAOYSA-N 0.000 description 1
- MOOAHMCRPCTRLV-UHFFFAOYSA-N boron sodium Chemical compound [B].[Na] MOOAHMCRPCTRLV-UHFFFAOYSA-N 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 150000007529 inorganic bases Chemical class 0.000 description 1
- 208000004296 neuralgia Diseases 0.000 description 1
- 150000007530 organic bases Chemical class 0.000 description 1
- 230000036407 pain Effects 0.000 description 1
- JEXVQSWXXUJEMA-UHFFFAOYSA-N pyrazol-3-one Chemical class O=C1C=CN=N1 JEXVQSWXXUJEMA-UHFFFAOYSA-N 0.000 description 1
- 239000000376 reactant Substances 0.000 description 1
- 239000000932 sedative agent Substances 0.000 description 1
- 230000001624 sedative effect Effects 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000009987 spinning Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
- C07D231/46—Oxygen atom in position 3 or 5 and nitrogen atom in position 4
- C07D231/48—Oxygen atom in position 3 or 5 and nitrogen atom in position 4 with hydrocarbon radicals attached to said nitrogen atom
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05B—ELECTRIC HEATING; ELECTRIC LIGHT SOURCES NOT OTHERWISE PROVIDED FOR; CIRCUIT ARRANGEMENTS FOR ELECTRIC LIGHT SOURCES, IN GENERAL
- H05B3/00—Ohmic-resistance heating
- H05B3/0004—Devices wherein the heating current flows through the material to be heated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEK0062072 | 1967-04-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL29750A0 IL29750A0 (en) | 1968-06-20 |
| IL29750A true IL29750A (en) | 1971-11-29 |
Family
ID=7230412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL29750A IL29750A (en) | 1967-04-22 | 1968-04-03 | 1-phenyl-2,3-dimethyl-4-(2-bicyclo(2.2.1)heptyl)-amino-3-pyrazolin-5-one and process for its preparation |
Country Status (8)
| Country | Link |
|---|---|
| BE (1) | BE713366A (cs) |
| CH (1) | CH487162A (cs) |
| DE (1) | DE1695314A1 (cs) |
| ES (1) | ES353584A1 (cs) |
| FR (1) | FR7416M (cs) |
| GB (1) | GB1155010A (cs) |
| IL (1) | IL29750A (cs) |
| NL (1) | NL6805391A (cs) |
-
1967
- 1967-04-22 DE DE19671695314 patent/DE1695314A1/de active Pending
-
1968
- 1968-04-03 CH CH488868A patent/CH487162A/de not_active IP Right Cessation
- 1968-04-03 IL IL29750A patent/IL29750A/en unknown
- 1968-04-08 BE BE713366D patent/BE713366A/xx unknown
- 1968-04-17 NL NL6805391A patent/NL6805391A/xx unknown
- 1968-04-18 GB GB08285/68A patent/GB1155010A/en not_active Expired
- 1968-04-22 ES ES353584A patent/ES353584A1/es not_active Expired
- 1968-04-22 FR FR148948A patent/FR7416M/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE1695314A1 (de) | 1971-03-18 |
| CH487162A (de) | 1970-03-15 |
| NL6805391A (cs) | 1968-10-23 |
| BE713366A (cs) | 1968-10-08 |
| IL29750A0 (en) | 1968-06-20 |
| FR7416M (cs) | 1969-11-12 |
| GB1155010A (en) | 1969-06-11 |
| ES353584A1 (es) | 1969-10-01 |
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