IL29485A - Process for the preparation of 2,3,4,5-tetrahydro-1h-3-benzazepines - Google Patents

Process for the preparation of 2,3,4,5-tetrahydro-1h-3-benzazepines

Info

Publication number
IL29485A
IL29485A IL29485A IL2948568A IL29485A IL 29485 A IL29485 A IL 29485A IL 29485 A IL29485 A IL 29485A IL 2948568 A IL2948568 A IL 2948568A IL 29485 A IL29485 A IL 29485A
Authority
IL
Israel
Prior art keywords
benzazepines
tetrahydro
preparation
Prior art date
Application number
IL29485A
Other languages
English (en)
Original Assignee
Geigy Ag J R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geigy Ag J R filed Critical Geigy Ag J R
Publication of IL29485A publication Critical patent/IL29485A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Drawers Of Furniture (AREA)
IL29485A 1967-02-17 1968-02-16 Process for the preparation of 2,3,4,5-tetrahydro-1h-3-benzazepines IL29485A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH238667A CH481110A (de) 1967-02-17 1967-02-17 Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
CH1167167A CH488705A (de) 1967-02-17 1967-08-18 Verfahren zur Herstellung eines neuen Tetrahydroazepinderivates

Publications (1)

Publication Number Publication Date
IL29485A true IL29485A (en) 1971-07-28

Family

ID=25690322

Family Applications (1)

Application Number Title Priority Date Filing Date
IL29485A IL29485A (en) 1967-02-17 1968-02-16 Process for the preparation of 2,3,4,5-tetrahydro-1h-3-benzazepines

Country Status (13)

Country Link
US (1) US3652543A (OSRAM)
AT (1) AT275533B (OSRAM)
BE (1) BE710872A (OSRAM)
CH (2) CH481110A (OSRAM)
DE (2) DE1668915A1 (OSRAM)
DK (1) DK115473B (OSRAM)
ES (1) ES350574A1 (OSRAM)
FR (2) FR1561479A (OSRAM)
GB (2) GB1221324A (OSRAM)
IL (1) IL29485A (OSRAM)
NL (1) NL6802257A (OSRAM)
NO (1) NO124369B (OSRAM)
SE (1) SE342043B (OSRAM)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT289812B (de) * 1968-08-09 1971-05-10 Geigy Ag J R Verfahren zur Herstellung des neuen 2-Methyl-7-chlor-2,3,4,5-tetrahydro-1H-3-benzazepins sowie seiner Säureadditionssalze
DE2016136A1 (de) * 1970-04-04 1971-10-14 C H Boehnnger Sohn, 6507 Ingel heim Neue 7 Acyl 1,2,4,5 tetrahydro (3H) 3 benzazepine
DE2143204C3 (de) * 1971-08-28 1979-09-27 Deutsche Gold- Und Silber-Scheideanstalt Vormals Roessler, 6000 Frankfurt N-Fluoralkyl-phenylisopropylamin-Derivate und deren Salze, Verfahren zu deren Herstellung und Arzneimittel auf deren Basis
DE2207430C3 (de) * 1972-02-14 1982-05-13 Pennwalt Corp., 19102 Philadelphia, Pa. 1,2,4,5-Tetrahydro-3H-3-benzazepin, ein Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Mittel
EP0161350A1 (en) * 1981-11-27 1985-11-21 Smithkline Beckman Corporation Process for preparing benzazepines
US4541954A (en) * 1984-09-05 1985-09-17 Smithkline Beckman Corporation Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
US4973586A (en) * 1986-01-16 1990-11-27 Schering Corporation Fused benzazepines, compositions of, and medical use thereof
US5302716A (en) * 1986-01-16 1994-04-12 Schering Corporation Fused benzazepines
WO1987004430A2 (en) * 1986-01-16 1987-07-30 Schering Corporation Fused benzazepines
US5015639A (en) * 1987-03-27 1991-05-14 Schering Corporation Substituted benzazepines, their preparation and pharmaceutical compositions containing them
WO1989000561A1 (en) * 1987-07-15 1989-01-26 Schering Corporation Fused benzazepines
US5362728A (en) * 1990-02-02 1994-11-08 Schering Corporation 4,5-bridged-2,3,4,5-tetrahydro-1H-3-benzazepine-7-ols and derivatives and compositions and methods employing such compounds
US6953787B2 (en) * 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
US20030220661A1 (en) * 2002-05-21 2003-11-27 Heartstent Corporation Transmyocardial implant delivery system
EA016485B1 (ru) * 2003-06-17 2012-05-30 Арена Фармасьютикалз, Инк. Способы получения 3-бензазепинов
CN1805938B (zh) * 2003-06-17 2010-06-16 艾尼纳制药公司 用于治疗5ht2c受体相关疾病的苯并氮杂卓衍生物
WO2005042490A1 (en) * 2003-10-22 2005-05-12 Arena Pharmaceuticals, Inc. Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
WO2005042491A1 (en) * 2003-10-22 2005-05-12 Arena Pharmaceuticals, Inc. Benzazepine derivatives and methods of prophylaxis or treatment of 5ht2c receptor associated diseases
EA201200954A1 (ru) 2004-12-21 2013-05-30 Арена Фармасьютикалз, Инк. Способ получения полугидрата гидрохлорида (r)-8-хлор-1-метил-2,3,4,5-тетрагидро-1н-3-бензазепина, фармацевтическая композиция на его основе и его применение
PL1833473T3 (pl) 2004-12-23 2010-02-26 Arena Pharm Inc Kompozycje modulatora receptora 5HT2C i sposoby zastosowania
CN101466684B (zh) * 2006-04-03 2012-06-20 艾尼纳制药公司 8-氯-1-甲基-2,3,4,5-四氢-1h-3-苯并氮杂卓的制备工艺和其相关中间体
US8299241B2 (en) * 2006-12-05 2012-10-30 Arena Pharmaceuticals, Inc. Processes for preparing (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and intermediates thereof
CN102015591B (zh) * 2008-03-04 2014-01-29 艾尼纳制药公司 制备与5-ht2c激动剂(r)-8-氯-1-甲基-2，3，4，5-四氢-1h-3-苯并氮杂卓相关的中间体的方法
CN102648170A (zh) 2009-06-18 2012-08-22 艾尼纳制药公司 制备5-ht2c受体激动剂的方法
US20120253036A1 (en) 2009-12-11 2012-10-04 Yukinori Nagakura Agent for treating fibromyalgia
KR20130112848A (ko) 2010-06-02 2013-10-14 아레나 파마슈티칼스, 인크. 5-ｈｔ2ｃ 수용체 아고니스트의 제조 방법
KR20130101524A (ko) 2010-09-01 2013-09-13 아레나 파마슈티칼스, 인크. 5-ｈｔ2ｃ 아고니스트의 비-흡습성 염
CA2808912C (en) 2010-09-01 2019-09-17 Zezhi Jesse Shao Modified-release dosage forms of 5-ht2c agonists useful for weight management
AU2011296015B2 (en) 2010-09-01 2015-11-12 Arena Pharmaceuticals, Inc. Administration of lorcaserin to individuals with renal impairment
US9248133B2 (en) 2010-09-01 2016-02-02 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
WO2014058441A1 (en) 2012-10-09 2014-04-17 Arena Pharmaceuticals, Inc. Method of weight management

Also Published As

Publication number Publication date
GB1221324A (en) 1971-02-03
CH481110A (de) 1969-11-15
DE1668915A1 (de) 1972-03-09
DE1695124A1 (de) 1970-08-20
BE710872A (OSRAM) 1968-08-16
FR1561479A (OSRAM) 1969-03-28
GB1222397A (en) 1971-02-10
SE342043B (OSRAM) 1972-01-24
FR1560654A (OSRAM) 1969-03-21
AT275533B (de) 1969-10-27
NO124369B (OSRAM) 1972-04-10
NL6802257A (OSRAM) 1968-08-19
DK115473B (da) 1969-10-13
CH488705A (de) 1970-04-15
ES350574A1 (es) 1969-11-16
US3652543A (en) 1972-03-28

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