IL292218B1 - Preparations for oral administration of active substances with a controlled absorption profile - Google Patents
Preparations for oral administration of active substances with a controlled absorption profileInfo
- Publication number
- IL292218B1 IL292218B1 IL292218A IL29221822A IL292218B1 IL 292218 B1 IL292218 B1 IL 292218B1 IL 292218 A IL292218 A IL 292218A IL 29221822 A IL29221822 A IL 29221822A IL 292218 B1 IL292218 B1 IL 292218B1
- Authority
- IL
- Israel
- Prior art keywords
- active agent
- therapeutically active
- composition
- range
- protease inhibitor
- Prior art date
Links
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
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- A—HUMAN NECESSITIES
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- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- General Health & Medical Sciences (AREA)
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- Molecular Biology (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Display Devices Of Pinball Game Machines (AREA)
- Superconductors And Manufacturing Methods Therefor (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (8)
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US201562113629P | 2015-02-09 | 2015-02-09 | |
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US201562113600P | 2015-02-09 | 2015-02-09 | |
US201562113619P | 2015-02-09 | 2015-02-09 | |
PCT/IL2016/050153 WO2016128972A1 (en) | 2015-02-09 | 2016-02-09 | Formulations for oral administration of active agents with controlled absorption profile |
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IL283258A IL283258B2 (en) | 2015-02-09 | 2016-02-09 | A preparation for the treatment of hypothyroidism |
IL253802A IL253802B (en) | 2015-02-09 | 2016-02-09 | A preparation for the treatment of osteoporosis |
IL292417A IL292417B1 (en) | 2015-02-09 | 2016-02-09 | A preparation for the treatment of osteoporosis |
IL253803A IL253803B (en) | 2015-02-09 | 2017-08-02 | A preparation for the treatment of hypothyroidism |
IL253804A IL253804B (en) | 2015-02-09 | 2017-08-02 | Preparations for oral administration of active substances with a controlled absorption profile |
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IL283258A IL283258B2 (en) | 2015-02-09 | 2016-02-09 | A preparation for the treatment of hypothyroidism |
IL253802A IL253802B (en) | 2015-02-09 | 2016-02-09 | A preparation for the treatment of osteoporosis |
IL292417A IL292417B1 (en) | 2015-02-09 | 2016-02-09 | A preparation for the treatment of osteoporosis |
IL253803A IL253803B (en) | 2015-02-09 | 2017-08-02 | A preparation for the treatment of hypothyroidism |
IL253804A IL253804B (en) | 2015-02-09 | 2017-08-02 | Preparations for oral administration of active substances with a controlled absorption profile |
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EP (5) | EP3256114A4 (ja) |
JP (6) | JP6925969B2 (ja) |
CN (5) | CN107427481A (ja) |
CA (5) | CA2975710C (ja) |
HK (5) | HK1247823A1 (ja) |
IL (7) | IL303216A (ja) |
MX (2) | MX2017010220A (ja) |
WO (5) | WO2016128974A1 (ja) |
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PT2651398T (pt) | 2010-12-16 | 2018-03-09 | Novo Nordisk As | Composições sólidas compreendendo um agonista de glp-1 e um sal de ácido n-(8-(2-hidroxibenzoil)amino) caprílico |
EP3225631B1 (en) | 2011-04-12 | 2019-01-09 | Novo Nordisk A/S | Double-acylated glp-1 derivatives |
PT2827845T (pt) | 2012-03-22 | 2019-03-29 | Novo Nordisk As | Composições compreendendo um agente de entrega e sua preparação |
EP2827885B1 (en) | 2012-03-22 | 2018-08-15 | Novo Nordisk A/S | Compositions of glp-1 peptides and preparation thereof |
WO2013189988A1 (en) | 2012-06-20 | 2013-12-27 | Novo Nordisk A/S | Tablet formulation comprising a peptide and a delivery agent |
WO2016128974A1 (en) | 2015-02-09 | 2016-08-18 | Entera Bio Ltd. | Formulations for oral administration of active agents |
CN116850132A (zh) * | 2016-08-17 | 2023-10-10 | 安提拉生物有限公司 | 用于口服的活性剂的制剂 |
SG11202006595RA (en) | 2018-02-02 | 2020-08-28 | Novo Nordisk As | Solid compositions comprising a glp-1 agonist, a salt of n-(8-(2-hydroxybenzoyl)amino)caprylic acid and a lubricant |
AU2020342512A1 (en) * | 2019-09-03 | 2022-03-31 | Amgen Inc. | IL-22 oral, intra-rectal, or other gut-related compositions and methods of use thereof |
CN114306249A (zh) * | 2020-09-28 | 2022-04-12 | 深圳翰宇药业股份有限公司 | 一种特立帕肽冻干药物组合物及其制备方法 |
CN114288388B (zh) * | 2022-01-25 | 2023-11-03 | 华中科技大学同济医学院附属协和医院 | 网膜素在制备炎症性肠病治疗药物中的应用 |
WO2023161938A1 (en) * | 2022-02-24 | 2023-08-31 | Entera Bio Ltd. | Formulations comprising acid-neutralizing polymer for oral administration of kappa opioid receptor agonist peptide |
WO2023161939A1 (en) * | 2022-02-24 | 2023-08-31 | Entera Bio Ltd. | Formulations comprising acid-neutralizing polymer for oral administration of glucagon-like peptide-1 and analogs thereof |
IL315200A (en) * | 2022-02-24 | 2024-10-01 | Entera Bio Ltd | Preparations containing polymers that neutralize acidity for oral administration of GLP-2 |
WO2023161935A1 (en) * | 2022-02-24 | 2023-08-31 | Entera Bio Ltd. | Formulations comprising acid-neutralizing polymer for oral administration of growth hormone |
WO2023161936A1 (en) * | 2022-02-24 | 2023-08-31 | Entera Bio Ltd. | Formulations comprising acid-neutralizing polymer for oral administration of growth hormone-releasing hormone |
WO2023161933A1 (en) * | 2022-02-24 | 2023-08-31 | Entera Bio Ltd. | Formulations comprising acid-neutralizing polymer for oral administration of parathyroid hormone |
WO2023161934A1 (en) * | 2022-02-24 | 2023-08-31 | Entera Bio Ltd. | Formulations comprising acid-neutralizing polymer for oral administration of active agents |
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2016
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- 2016-02-09 CN CN202210601969.9A patent/CN114949185A/zh active Pending
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- 2016-02-09 IL IL253802A patent/IL253802B/en unknown
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- 2016-02-09 IL IL292417A patent/IL292417B1/en unknown
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2017
- 2017-08-02 IL IL253803A patent/IL253803B/en active IP Right Grant
- 2017-08-02 IL IL253804A patent/IL253804B/en unknown
- 2017-08-08 MX MX2022014313A patent/MX2022014313A/es unknown
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2018
- 2018-06-04 HK HK18107251.9A patent/HK1247823A1/zh unknown
- 2018-06-04 HK HK18107250.0A patent/HK1247822A1/zh unknown
- 2018-06-06 HK HK18107372.3A patent/HK1247838A1/zh unknown
- 2018-06-06 HK HK18107355.4A patent/HK1247835A1/zh unknown
- 2018-06-07 HK HK18107403.6A patent/HK1247843A1/zh unknown
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2019
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2021
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2023
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2024
- 2024-02-05 US US18/432,185 patent/US20240181020A1/en active Pending
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