IL290717B2 - Cell compositions derived from dedifferentiated reprogrammed cells - Google Patents

Cell compositions derived from dedifferentiated reprogrammed cells

Info

Publication number
IL290717B2
IL290717B2 IL290717A IL29071722A IL290717B2 IL 290717 B2 IL290717 B2 IL 290717B2 IL 290717 A IL290717 A IL 290717A IL 29071722 A IL29071722 A IL 29071722A IL 290717 B2 IL290717 B2 IL 290717B2
Authority
IL
Israel
Prior art keywords
cells
cell
endoderm
human
pdx1
Prior art date
Application number
IL290717A
Other languages
English (en)
Hebrew (he)
Other versions
IL290717B1 (en
IL290717A (en
Original Assignee
Viacyte Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/761,078 external-priority patent/US9109245B2/en
Application filed by Viacyte Inc filed Critical Viacyte Inc
Publication of IL290717A publication Critical patent/IL290717A/en
Publication of IL290717B1 publication Critical patent/IL290717B1/en
Publication of IL290717B2 publication Critical patent/IL290717B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL290717A 2013-02-06 2014-02-06 Cell compositions derived from dedifferentiated reprogrammed cells IL290717B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/761,078 US9109245B2 (en) 2009-04-22 2013-02-06 Cell compositions derived from dedifferentiated reprogrammed cells
PCT/US2014/015156 WO2014124172A1 (en) 2013-02-06 2014-02-06 Cell compositions derived from dedifferentiated reprogrammed cells

Publications (3)

Publication Number Publication Date
IL290717A IL290717A (en) 2022-04-01
IL290717B1 IL290717B1 (en) 2024-06-01
IL290717B2 true IL290717B2 (en) 2024-10-01

Family

ID=50239931

Family Applications (5)

Application Number Title Priority Date Filing Date
IL290717A IL290717B2 (en) 2013-02-06 2014-02-06 Cell compositions derived from dedifferentiated reprogrammed cells
IL239953A IL239953B (en) 2013-02-06 2015-07-15 Cell assemblies derived from reprogrammed undifferentiated cells
IL283088A IL283088B (en) 2013-02-06 2021-05-10 Cell compositions derived from dedifferentiated reprogrammed cells
IL311689A IL311689B1 (en) 2013-02-06 2024-03-25 Cell preparations derived from dedifferentiated and reprogrammed cells
IL321825A IL321825A (en) 2013-02-06 2025-06-29 Cell preparations derived from dedifferentiated and reprogrammed cells

Family Applications After (4)

Application Number Title Priority Date Filing Date
IL239953A IL239953B (en) 2013-02-06 2015-07-15 Cell assemblies derived from reprogrammed undifferentiated cells
IL283088A IL283088B (en) 2013-02-06 2021-05-10 Cell compositions derived from dedifferentiated reprogrammed cells
IL311689A IL311689B1 (en) 2013-02-06 2024-03-25 Cell preparations derived from dedifferentiated and reprogrammed cells
IL321825A IL321825A (en) 2013-02-06 2025-06-29 Cell preparations derived from dedifferentiated and reprogrammed cells

Country Status (8)

Country Link
EP (1) EP2954045A1 (enrdf_load_stackoverflow)
JP (5) JP6517702B2 (enrdf_load_stackoverflow)
AU (4) AU2014214879A1 (enrdf_load_stackoverflow)
CA (2) CA2898431C (enrdf_load_stackoverflow)
HK (1) HK1218139A1 (enrdf_load_stackoverflow)
IL (5) IL290717B2 (enrdf_load_stackoverflow)
RU (2) RU2675928C2 (enrdf_load_stackoverflow)
WO (1) WO2014124172A1 (enrdf_load_stackoverflow)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9109245B2 (en) 2009-04-22 2015-08-18 Viacyte, Inc. Cell compositions derived from dedifferentiated reprogrammed cells
CN106795487B (zh) 2014-08-04 2021-11-19 武田药品工业株式会社 胰腺祖细胞的增殖方法
MA45479A (fr) * 2016-04-14 2019-02-20 Janssen Biotech Inc Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen
EP3460042B1 (en) * 2016-05-18 2024-02-21 Keio University Cell culture medium for culturing organoid, culture method, and organoid
EP3587560A4 (en) 2017-01-27 2020-12-16 Kaneka Corporation Endodermal cell mass, and method for producing any one of three primary germ layer cell mass from pluripotent cells
CA3066055A1 (en) 2017-06-14 2018-12-20 Semma Therapeutics, Inc. Devices and methods for delivering therapeutics
EP3654996A4 (en) * 2017-07-21 2021-03-24 Semma Therapeutics, Inc. REAGGREGATION OF PANCREAS BETA CELLS FROM STEM CELLS
AU2019313964A1 (en) * 2018-08-03 2021-03-18 Kyoto University Cell production method
JP7295576B2 (ja) * 2018-09-19 2023-06-21 オリヅルセラピューティクス株式会社 インスリン産生細胞
AU2020282355B2 (en) 2019-05-31 2023-11-02 Viacyte, Inc. A biocompatible membrane composite
CA3139585C (en) 2019-05-31 2024-01-23 W. L. Gore & Associates, Inc. A biocompatible membrane composite
JP7328362B2 (ja) 2019-05-31 2023-08-16 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド 制御された酸素拡散距離を伴う細胞カプセル化デバイス
WO2020243665A1 (en) 2019-05-31 2020-12-03 W. L. Gore & Associates, Inc. A biocompatible membrane composite
CA3186967A1 (en) 2020-07-31 2022-02-03 George Harb Differentiation of pancreatic endocrine cells

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100272695A1 (en) * 2009-04-22 2010-10-28 Alan Agulnick Cell compositions derived from dedifferentiated reprogrammed cells

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1165113E (pt) * 1999-04-06 2008-09-23 Genentech Inc Utilização de ligandos de receptor erbb no tratamento da diabetes
US6759039B2 (en) * 2000-06-30 2004-07-06 Amcyte, Inc. Culturing pancreatic stem cells having a specified, intermediate stage of development
US20040121460A1 (en) * 2001-01-24 2004-06-24 Lumelsky Nadya L Differentiation of stem cells to pancreatic endocrine cells
US8409859B2 (en) * 2005-10-14 2013-04-02 Regents Of The University Of Minnesota Differentiation of non-embryonic stem cells to cells having a pancreatic phenotype
AU2007254766A1 (en) * 2006-06-02 2007-12-13 University Of Georgia Research Foundation, Inc. Pancreatic and liver endoderm cells and tissue by differentiation of definitive endoderm cells obtained from human embryonic stems
JP2012508584A (ja) 2008-11-14 2012-04-12 ヴィアサイト，インコーポレイテッド ヒト多能性幹細胞由来膵臓細胞のカプセル化
JP5961110B2 (ja) * 2009-04-27 2016-08-02 バイアサイト インク 低分子サポート多能性細胞成育およびその方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100272695A1 (en) * 2009-04-22 2010-10-28 Alan Agulnick Cell compositions derived from dedifferentiated reprogrammed cells

Also Published As

Publication number Publication date
JP6721752B2 (ja) 2020-07-15
IL311689B1 (en) 2025-08-01
HK1218139A1 (zh) 2017-02-03
AU2022200075B2 (en) 2023-02-02
JP2016506736A (ja) 2016-03-07
WO2014124172A1 (en) 2014-08-14
JP7250731B2 (ja) 2023-04-03
EP2954045A1 (en) 2015-12-16
IL239953A0 (en) 2015-08-31
JP2020178694A (ja) 2020-11-05
IL290717B1 (en) 2024-06-01
CA2898431C (en) 2023-10-17
IL290717A (en) 2022-04-01
CA2898431A1 (en) 2014-08-14
RU2754089C2 (ru) 2021-08-26
AU2019201314A1 (en) 2019-03-14
CA3212301A1 (en) 2014-08-14
IL311689A (en) 2024-05-01
JP2023017838A (ja) 2023-02-07
JP7550830B2 (ja) 2024-09-13
JP6517702B2 (ja) 2019-05-22
AU2022200075C1 (en) 2023-07-06
RU2018144412A (ru) 2019-03-25
IL283088B (en) 2022-04-01
RU2675928C2 (ru) 2018-12-25
AU2023202507A1 (en) 2023-05-11
RU2015131279A (ru) 2017-03-13
JP2019146578A (ja) 2019-09-05
IL239953B (en) 2021-05-31
AU2019201314B2 (en) 2021-10-14
AU2014214879A1 (en) 2015-07-30
JP2025000625A (ja) 2025-01-07
RU2018144412A3 (enrdf_load_stackoverflow) 2020-02-14
AU2022200075A1 (en) 2022-02-03
IL321825A (en) 2025-08-01
IL283088A (en) 2021-06-30

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