JP6517702B2 - 脱分化したリプログラミングされた細胞から導出された細胞組成物 - Google Patents

脱分化したリプログラミングされた細胞から導出された細胞組成物 Download PDF

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JP6517702B2
JP6517702B2 JP2015556262A JP2015556262A JP6517702B2 JP 6517702 B2 JP6517702 B2 JP 6517702B2 JP 2015556262 A JP2015556262 A JP 2015556262A JP 2015556262 A JP2015556262 A JP 2015556262A JP 6517702 B2 JP6517702 B2 JP 6517702B2
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cells
cell
endoderm
pluripotent
pdx1
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JP2016506736A (ja
JP2016506736A5 (enrdf_load_stackoverflow
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アラン ディー． アグルニック、
アラン ディー． アグルニック、
オリビア ケリー、
オリビア ケリー、
ユキ オオイ
ユキ オオイ
アラン ロビンス、
アラン ロビンス、
トーマス シュルツ、
トーマス シュルツ、
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ヴィアサイト インコーポレイテッド
ヴィアサイト インコーポレイテッド
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0012—Cell encapsulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases [EC 2.]
    • C12N2501/727—Kinases (EC 2.7.)
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP2015556262A 2013-02-06 2014-02-06 脱分化したリプログラミングされた細胞から導出された細胞組成物 Active JP6517702B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/761,078 US9109245B2 (en) 2009-04-22 2013-02-06 Cell compositions derived from dedifferentiated reprogrammed cells
US13/761,078 2013-02-06
PCT/US2014/015156 WO2014124172A1 (en) 2013-02-06 2014-02-06 Cell compositions derived from dedifferentiated reprogrammed cells

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JP2019078983A Division JP6721752B2 (ja) 2013-02-06 2019-04-18 脱分化したリプログラミングされた細胞から導出された細胞組成物

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JP2016506736A JP2016506736A (ja) 2016-03-07
JP2016506736A5 JP2016506736A5 (enrdf_load_stackoverflow) 2017-03-09
JP6517702B2 true JP6517702B2 (ja) 2019-05-22

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JP2015556262A Active JP6517702B2 (ja) 2013-02-06 2014-02-06 脱分化したリプログラミングされた細胞から導出された細胞組成物
JP2019078983A Active JP6721752B2 (ja) 2013-02-06 2019-04-18 脱分化したリプログラミングされた細胞から導出された細胞組成物
JP2020104982A Active JP7250731B2 (ja) 2013-02-06 2020-06-18 脱分化したリプログラミングされた細胞から導出された細胞組成物
JP2022172222A Active JP7550830B2 (ja) 2013-02-06 2022-10-27 脱分化したリプログラミングされた細胞から導出された細胞組成物
JP2024151116A Pending JP2025000625A (ja) 2013-02-06 2024-09-03 脱分化したリプログラミングされた細胞から導出された細胞組成物

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JP2019078983A Active JP6721752B2 (ja) 2013-02-06 2019-04-18 脱分化したリプログラミングされた細胞から導出された細胞組成物
JP2020104982A Active JP7250731B2 (ja) 2013-02-06 2020-06-18 脱分化したリプログラミングされた細胞から導出された細胞組成物
JP2022172222A Active JP7550830B2 (ja) 2013-02-06 2022-10-27 脱分化したリプログラミングされた細胞から導出された細胞組成物
JP2024151116A Pending JP2025000625A (ja) 2013-02-06 2024-09-03 脱分化したリプログラミングされた細胞から導出された細胞組成物

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EP (1) EP2954045A1 (enrdf_load_stackoverflow)
JP (5) JP6517702B2 (enrdf_load_stackoverflow)
AU (4) AU2014214879A1 (enrdf_load_stackoverflow)
CA (2) CA2898431C (enrdf_load_stackoverflow)
HK (1) HK1218139A1 (enrdf_load_stackoverflow)
IL (5) IL290717B2 (enrdf_load_stackoverflow)
RU (2) RU2675928C2 (enrdf_load_stackoverflow)
WO (1) WO2014124172A1 (enrdf_load_stackoverflow)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9109245B2 (en) 2009-04-22 2015-08-18 Viacyte, Inc. Cell compositions derived from dedifferentiated reprogrammed cells
US10655105B2 (en) 2014-08-04 2020-05-19 Takeda Pharmaceutical Company Limited Method for proliferation of pancreatic progenitor cells
MA45479A (fr) * 2016-04-14 2019-02-20 Janssen Biotech Inc Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen
CN111334463B (zh) * 2016-05-18 2024-02-20 学校法人庆应义塾 类器官培养用细胞培养基、培养方法及类器官
WO2018139600A1 (ja) 2017-01-27 2018-08-02 株式会社カネカ 内胚葉系細胞集団、及び多能性細胞から三胚葉のいずれかの細胞集団を製造する方法
CA3066055A1 (en) 2017-06-14 2018-12-20 Semma Therapeutics, Inc. Devices and methods for delivering therapeutics
EP3654996A4 (en) * 2017-07-21 2021-03-24 Semma Therapeutics, Inc. REAGGREGATION OF PANCREAS BETA CELLS FROM STEM CELLS
AU2019313964A1 (en) * 2018-08-03 2021-03-18 Kyoto University Cell production method
MX2021003147A (es) * 2018-09-19 2021-05-14 Takeda Pharmaceuticals Co Celulas productoras de insulina.
JP2022535239A (ja) 2019-05-31 2022-08-05 ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド 生体適合性メンブレン複合体
US20220234006A1 (en) 2019-05-31 2022-07-28 W. L. Gore & Associates, Inc. A biocompatible membrane composite
WO2020243665A1 (en) 2019-05-31 2020-12-03 W. L. Gore & Associates, Inc. A biocompatible membrane composite
CA3139292A1 (en) 2019-05-31 2020-12-03 Timothy M. BRUHN Cell encapsulation devices with controlled oxygen diffusion distances
CA3186967A1 (en) 2020-07-31 2022-02-03 George Harb Differentiation of pancreatic endocrine cells

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4794049B2 (ja) * 1999-04-06 2011-10-12 ジェネンテック， インコーポレイテッド 糖尿病治療へのＥｒｂＢレセプターリガンドの使用
US6759039B2 (en) * 2000-06-30 2004-07-06 Amcyte, Inc. Culturing pancreatic stem cells having a specified, intermediate stage of development
JP2005503759A (ja) * 2001-01-24 2005-02-10 アメリカ合衆国 幹細胞の膵臓内分泌細胞への分化方法
AU2006304318B2 (en) * 2005-10-14 2012-12-06 Regents Of The University Of Minnesota Differentiation of non-embryonic stem cells to cells having a pancreatic phenotype
WO2007143193A1 (en) * 2006-06-02 2007-12-13 University Of Georgia Research Foundation, Inc. Pancreatic and liver endoderm cells and tissue by differentiation of definitive endoderm cells obtained from human embryonic stems
EP2356227B1 (en) 2008-11-14 2018-03-28 Viacyte, Inc. Encapsulation of pancreatic cells derived from human pluripotent stem cells
EP2421957B1 (en) * 2009-04-22 2020-11-18 Viacyte, Inc. Cell compositions derived from dedifferentiated reprogrammed cells
CN102741396B (zh) * 2009-04-27 2017-10-20 威盛细胞有限公司 支持多能细胞生长的小分子和其方法

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AU2022200075B2 (en) 2023-02-02
IL321825A (en) 2025-08-01
IL290717A (en) 2022-04-01
CA2898431A1 (en) 2014-08-14
JP2016506736A (ja) 2016-03-07
JP2019146578A (ja) 2019-09-05
RU2754089C2 (ru) 2021-08-26
IL311689A (en) 2024-05-01
IL290717B1 (en) 2024-06-01
CA2898431C (en) 2023-10-17
JP2025000625A (ja) 2025-01-07
IL239953A0 (en) 2015-08-31
JP2020178694A (ja) 2020-11-05
IL290717B2 (en) 2024-10-01
CA3212301A1 (en) 2014-08-14
AU2014214879A1 (en) 2015-07-30
JP7250731B2 (ja) 2023-04-03
IL311689B1 (en) 2025-08-01
RU2018144412A (ru) 2019-03-25
AU2019201314A1 (en) 2019-03-14
RU2675928C2 (ru) 2018-12-25
RU2015131279A (ru) 2017-03-13
JP6721752B2 (ja) 2020-07-15
JP7550830B2 (ja) 2024-09-13
IL239953B (en) 2021-05-31
IL283088A (en) 2021-06-30
IL283088B (en) 2022-04-01
JP2023017838A (ja) 2023-02-07
RU2018144412A3 (enrdf_load_stackoverflow) 2020-02-14
AU2022200075C1 (en) 2023-07-06
AU2022200075A1 (en) 2022-02-03
AU2023202507A1 (en) 2023-05-11
EP2954045A1 (en) 2015-12-16
AU2019201314B2 (en) 2021-10-14
WO2014124172A1 (en) 2014-08-14
HK1218139A1 (zh) 2017-02-03

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