IL290319B2 - 7-[(8-Azabicyclo[1.2.3]octan-3-yl)oxy]-h2-1-benzopyran-2-one for use in the treatment of combined impotence and depression - Google Patents
7-[(8-Azabicyclo[1.2.3]octan-3-yl)oxy]-h2-1-benzopyran-2-one for use in the treatment of combined impotence and depressionInfo
- Publication number
- IL290319B2 IL290319B2 IL290319A IL29031922A IL290319B2 IL 290319 B2 IL290319 B2 IL 290319B2 IL 290319 A IL290319 A IL 290319A IL 29031922 A IL29031922 A IL 29031922A IL 290319 B2 IL290319 B2 IL 290319B2
- Authority
- IL
- Israel
- Prior art keywords
- compound
- use according
- subject
- age
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19190224 | 2019-08-06 | ||
| PCT/EP2020/072092 WO2021023805A1 (en) | 2019-08-06 | 2020-08-06 | Compound for combination treatment |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL290319A IL290319A (en) | 2022-04-01 |
| IL290319B2 true IL290319B2 (en) | 2023-06-01 |
Family
ID=67551141
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL290319A IL290319B2 (en) | 2019-08-06 | 2022-02-03 | 7-[(8-Azabicyclo[1.2.3]octan-3-yl)oxy]-h2-1-benzopyran-2-one for use in the treatment of combined impotence and depression |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20220288052A1 (https=) |
| EP (2) | EP4009942B1 (https=) |
| JP (1) | JP7605825B2 (https=) |
| KR (1) | KR20220054593A (https=) |
| CN (1) | CN114430679A (https=) |
| AU (1) | AU2020326244B2 (https=) |
| BR (1) | BR112022002169A2 (https=) |
| CA (1) | CA3146837A1 (https=) |
| DK (1) | DK4009942T3 (https=) |
| ES (1) | ES2962648T3 (https=) |
| FI (1) | FI4009942T3 (https=) |
| IL (1) | IL290319B2 (https=) |
| MX (1) | MX2022000356A (https=) |
| PL (1) | PL4009942T3 (https=) |
| WO (1) | WO2021023805A1 (https=) |
| ZA (1) | ZA202200723B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4646204A1 (en) * | 2023-01-03 | 2025-11-12 | Initiator Pharma A/S | Compound for treatment of erectile dysfunction |
| WO2025051846A1 (en) | 2023-09-05 | 2025-03-13 | Initiator Pharma A/S | Compound for treatment of female sexual dysfunction |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04012693A (es) * | 2002-06-20 | 2005-03-23 | Lundbeck & Co As H | Terapia de combinacion en donde se utiliza un inhibidor de recaptacion de serotonina. |
| RU2354377C2 (ru) * | 2003-07-11 | 2009-05-10 | Берингер Ингельхайм Ветмедика Гмбх | Способ лечения или предупреждения заболеваний центральной нервной системы с использованием соединений, обладающих селективностью в отношении альфа-3-субъединицы бензодиазепинового рецептора |
| BRPI0515261A (pt) * | 2004-09-30 | 2008-07-15 | Neurosearch As | composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, uso do composto quìmico ou de qualquer um de seus isÈmeros ou de qualquer mistura de seus isÈmeros, ou um sal farmaceuticamente aceitável do mesmo, e, método para o tratamento, a prevenção ou o alìvio de uma doença ou de um distúrbio ou de uma condição de um corpo de animal vivo |
| WO2008074798A1 (en) * | 2006-12-20 | 2008-06-26 | Neurosearch A/S | Novel chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
| BRPI0917802A2 (pt) * | 2008-08-21 | 2016-03-01 | Neurosearch As | método para tratar um distúrbio de ansiedade, composição farmacêutica, uso do composto, uso de uma combinação, kit de partes, método para tratar, prevenir ou aliviar um distúrbio de ansiedade de um corpo de animal vivo, e, combinação |
| US20130040985A1 (en) | 2010-01-29 | 2013-02-14 | Neurosearch A/S | Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
-
2020
- 2020-08-06 WO PCT/EP2020/072092 patent/WO2021023805A1/en not_active Ceased
- 2020-08-06 CA CA3146837A patent/CA3146837A1/en active Pending
- 2020-08-06 EP EP20751149.4A patent/EP4009942B1/en active Active
- 2020-08-06 US US17/632,323 patent/US20220288052A1/en active Pending
- 2020-08-06 KR KR1020227005609A patent/KR20220054593A/ko active Pending
- 2020-08-06 PL PL20751149.4T patent/PL4009942T3/pl unknown
- 2020-08-06 AU AU2020326244A patent/AU2020326244B2/en active Active
- 2020-08-06 CN CN202080056000.7A patent/CN114430679A/zh active Pending
- 2020-08-06 DK DK20751149.4T patent/DK4009942T3/da active
- 2020-08-06 JP JP2022506360A patent/JP7605825B2/ja active Active
- 2020-08-06 BR BR112022002169A patent/BR112022002169A2/pt unknown
- 2020-08-06 ES ES20751149T patent/ES2962648T3/es active Active
- 2020-08-06 EP EP23183643.8A patent/EP4241839A3/en active Pending
- 2020-08-06 MX MX2022000356A patent/MX2022000356A/es unknown
- 2020-08-06 FI FIEP20751149.4T patent/FI4009942T3/fi active
-
2022
- 2022-01-14 ZA ZA2022/00723A patent/ZA202200723B/en unknown
- 2022-02-03 IL IL290319A patent/IL290319B2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021023805A1 (en) | 2021-02-11 |
| MX2022000356A (es) | 2022-05-11 |
| FI4009942T3 (fi) | 2023-09-26 |
| CN114430679A (zh) | 2022-05-03 |
| ES2962648T3 (es) | 2024-03-20 |
| BR112022002169A2 (pt) | 2022-06-07 |
| AU2020326244B2 (en) | 2025-06-05 |
| AU2020326244A1 (en) | 2022-03-17 |
| IL290319A (en) | 2022-04-01 |
| DK4009942T3 (da) | 2023-10-23 |
| EP4009942B1 (en) | 2023-08-09 |
| EP4009942A1 (en) | 2022-06-15 |
| CA3146837A1 (en) | 2021-02-11 |
| ZA202200723B (en) | 2022-08-31 |
| EP4241839A2 (en) | 2023-09-13 |
| JP7605825B2 (ja) | 2024-12-24 |
| US20220288052A1 (en) | 2022-09-15 |
| JP2022544463A (ja) | 2022-10-19 |
| PL4009942T3 (pl) | 2024-04-08 |
| EP4241839A3 (en) | 2023-11-15 |
| KR20220054593A (ko) | 2022-05-03 |
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