IL287126A - A process for the continuous production of a nucleus of an active ingredient - Google Patents

A process for the continuous production of a nucleus of an active ingredient

Info

Publication number
IL287126A
IL287126A IL287126A IL28712621A IL287126A IL 287126 A IL287126 A IL 287126A IL 287126 A IL287126 A IL 287126A IL 28712621 A IL28712621 A IL 28712621A IL 287126 A IL287126 A IL 287126A
Authority
IL
Israel
Prior art keywords
active ingredient
continuous production
ingredient granulate
granulate
continuous
Prior art date
Application number
IL287126A
Other languages
English (en)
Hebrew (he)
Original Assignee
Add Advanced Drug Delivery Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Add Advanced Drug Delivery Tech Ltd filed Critical Add Advanced Drug Delivery Tech Ltd
Publication of IL287126A publication Critical patent/IL287126A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glanulating (AREA)
IL287126A 2019-04-11 2021-10-10 A process for the continuous production of a nucleus of an active ingredient IL287126A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19168673.2A EP3721870A1 (de) 2019-04-11 2019-04-11 Verfahren zur kontinuierlichen herstellung eines wirkstoffgranulats
PCT/EP2020/060277 WO2020208201A1 (de) 2019-04-11 2020-04-09 Verfahren zur kontinuierlichen herstellung eines wirkstoffgranulats

Publications (1)

Publication Number Publication Date
IL287126A true IL287126A (en) 2022-01-01

Family

ID=66105201

Family Applications (1)

Application Number Title Priority Date Filing Date
IL287126A IL287126A (en) 2019-04-11 2021-10-10 A process for the continuous production of a nucleus of an active ingredient

Country Status (9)

Country Link
US (1) US20220323361A1 (enExample)
EP (2) EP3721870A1 (enExample)
JP (1) JP7620565B2 (enExample)
CN (1) CN114126591A (enExample)
AU (1) AU2020272151B2 (enExample)
BR (1) BR112021020320A2 (enExample)
CA (1) CA3136529A1 (enExample)
IL (1) IL287126A (enExample)
WO (1) WO2020208201A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3721871A1 (de) * 2019-04-11 2020-10-14 ADD Advanced Drug Delivery Technologies, Ltd. Verfahren zur kontinuierlichen herstellung eines wirkstoffgranulats
KR102857295B1 (ko) 2020-11-24 2025-09-08 나노폼 핀란드 오와이제이 입자 생성을 위한 시스템, 장치, 기기 및 방법
CN116422227B (zh) * 2022-12-09 2024-01-30 山东奥诺能源科技股份有限公司 一种流化床造粒机

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19514187C1 (de) * 1995-04-21 1996-05-15 Degussa Verfahren und Vorrichtung zur Herstellung von Granulaten durch Wirbelschicht-Sprühgranulation
US6117451A (en) 1998-08-25 2000-09-12 Pharmalogix, Inc. Direct compression metformin hydrochloride tablets
DE10004939C1 (de) 2000-02-05 2001-08-23 Lothar Moerl Steuerbare Gasanströmeinrichtung für Strahlschichtapparate
EP1238662B1 (en) 2001-03-07 2006-05-31 Dainippon Sumitomo Pharma Co., Ltd. Method for manufacturing drug granules, the drug granules and pharmaceutical preparation containing the drug granules
US6667054B2 (en) 2001-12-05 2003-12-23 Bernard Charles Sherman Metformin hydrochloride tablets
DE10322062A1 (de) 2003-05-15 2004-12-02 Glatt Ingenieurtechnik Gmbh Verfahren und Vorrichtung zum Aufbringen von Flüssigkeiten in eine Feststoffströmung eines Strahlschichtapparates
PT1638678E (pt) 2003-06-11 2012-01-05 Glatt Ingtech Gmbh Método para produção de granulados enzimáticos e granulados enzimáticos assim obtidos
EP1781253A1 (en) * 2004-07-01 2007-05-09 Warner-Lambert Company LLC Preparation of pharmaceutical compositions containing nanoparticles
DE102007012105A1 (de) 2007-03-13 2008-09-18 Add Advanced Drug Delivery Technologies Ltd. Pellets enthaltend pharmazeutische Substanz, Verfahren zu deren Herstellung und deren Verwendung
CN102970981A (zh) * 2010-07-06 2013-03-13 詹森药业有限公司 糖尿病协同治疗制剂
WO2013143688A1 (en) * 2012-03-26 2013-10-03 Glatt Ag Taste-masked ibuprofen granules
WO2015012365A1 (ja) * 2013-07-25 2015-01-29 株式会社 三和化学研究所 医薬製剤
KR101642193B1 (ko) 2014-10-13 2016-07-25 씨제이헬스케어 주식회사 메트포르민 서방성 제제 및 그의 제조방법
WO2018034627A1 (en) * 2016-08-18 2018-02-22 İlko Ilaç Sanayi Ve Ticaret Anonim Şirketi Pharmaceutical composition of antidiabetic tablet

Also Published As

Publication number Publication date
EP3721870A1 (de) 2020-10-14
WO2020208201A1 (de) 2020-10-15
CA3136529A1 (en) 2020-10-15
JP7620565B2 (ja) 2025-01-23
EP3952843B1 (de) 2025-08-06
EP3952843A1 (de) 2022-02-16
CN114126591A (zh) 2022-03-01
AU2020272151A1 (en) 2021-12-09
AU2020272151B2 (en) 2025-07-03
BR112021020320A2 (pt) 2021-12-14
JP2022528570A (ja) 2022-06-14
US20220323361A1 (en) 2022-10-13

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