IL270355B2 - Treatment of multiple sclerosis using long-acting glatiramer and stem cells derived from adipose tissue - Google Patents

Treatment of multiple sclerosis using long-acting glatiramer and stem cells derived from adipose tissue

Info

Publication number
IL270355B2
IL270355B2 IL270355A IL27035519A IL270355B2 IL 270355 B2 IL270355 B2 IL 270355B2 IL 270355 A IL270355 A IL 270355A IL 27035519 A IL27035519 A IL 27035519A IL 270355 B2 IL270355 B2 IL 270355B2
Authority
IL
Israel
Prior art keywords
administration
pharmaceutical composition
hadscs
depot
adscs
Prior art date
Application number
IL270355A
Other languages
English (en)
Hebrew (he)
Other versions
IL270355A (cg-RX-API-DMAC10.html
IL270355B1 (cg-RX-API-DMAC10.html
Inventor
Grynspan Frida
Marom Ehud
Bleich Kimelman Nadav
Original Assignee
Stem Cell Medicine Ltd
Mapi Pharma Ltd
Grynspan Frida
Marom Ehud
Bleich Kimelman Nadav
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stem Cell Medicine Ltd, Mapi Pharma Ltd, Grynspan Frida, Marom Ehud, Bleich Kimelman Nadav filed Critical Stem Cell Medicine Ltd
Publication of IL270355A publication Critical patent/IL270355A/en
Publication of IL270355B1 publication Critical patent/IL270355B1/en
Publication of IL270355B2 publication Critical patent/IL270355B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0085—Brain, e.g. brain implants; Spinal cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Epoxy Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL270355A 2017-05-15 2019-10-31 Treatment of multiple sclerosis using long-acting glatiramer and stem cells derived from adipose tissue IL270355B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IL2017/050535 WO2018211486A1 (en) 2017-05-15 2017-05-15 Treatment of multiple sclerosis with long acting glatiramer and adipose-derived stem cells

Publications (3)

Publication Number Publication Date
IL270355A IL270355A (cg-RX-API-DMAC10.html) 2019-12-31
IL270355B1 IL270355B1 (cg-RX-API-DMAC10.html) 2023-02-01
IL270355B2 true IL270355B2 (en) 2023-06-01

Family

ID=64273438

Family Applications (1)

Application Number Title Priority Date Filing Date
IL270355A IL270355B2 (en) 2017-05-15 2019-10-31 Treatment of multiple sclerosis using long-acting glatiramer and stem cells derived from adipose tissue

Country Status (8)

Country Link
US (1) US11413311B2 (cg-RX-API-DMAC10.html)
EP (1) EP3624815A4 (cg-RX-API-DMAC10.html)
JP (1) JP7000458B2 (cg-RX-API-DMAC10.html)
CN (1) CN110709091A (cg-RX-API-DMAC10.html)
AU (1) AU2017414803B2 (cg-RX-API-DMAC10.html)
CA (1) CA3062964C (cg-RX-API-DMAC10.html)
IL (1) IL270355B2 (cg-RX-API-DMAC10.html)
WO (1) WO2018211486A1 (cg-RX-API-DMAC10.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
AU2017319728B2 (en) 2016-08-31 2024-09-05 Mapi Pharma Ltd Depot systems comprising glatiramer acetate
IL316573A (en) * 2017-03-26 2024-12-01 Mapi Pharma Ltd Storage systems containing glatiramer acetate for the treatment of multiple sclerosis

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Also Published As

Publication number Publication date
AU2017414803A1 (en) 2019-12-05
CA3062964C (en) 2024-11-12
JP2020519658A (ja) 2020-07-02
US20200147141A1 (en) 2020-05-14
EP3624815A1 (en) 2020-03-25
US11413311B2 (en) 2022-08-16
IL270355A (cg-RX-API-DMAC10.html) 2019-12-31
WO2018211486A1 (en) 2018-11-22
JP7000458B2 (ja) 2022-02-10
AU2017414803B2 (en) 2025-02-13
CA3062964A1 (en) 2018-11-22
IL270355B1 (cg-RX-API-DMAC10.html) 2023-02-01
CN110709091A (zh) 2020-01-17
EP3624815A4 (en) 2021-01-20

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