IL264359B2 - Combination test for colorectal cancer - Google Patents
Combination test for colorectal cancerInfo
- Publication number
- IL264359B2 IL264359B2 IL264359A IL26435919A IL264359B2 IL 264359 B2 IL264359 B2 IL 264359B2 IL 264359 A IL264359 A IL 264359A IL 26435919 A IL26435919 A IL 26435919A IL 264359 B2 IL264359 B2 IL 264359B2
- Authority
- IL
- Israel
- Prior art keywords
- crc
- patient
- level
- fecal
- colonoscopy
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57535—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the large intestine, e.g. colon, rectum or anus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
- G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6875—Nucleoproteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Hospice & Palliative Care (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1612815.9A GB201612815D0 (en) | 2016-07-25 | 2016-07-25 | Novel combination test |
| PCT/EP2017/068754 WO2018019827A1 (en) | 2016-07-25 | 2017-07-25 | Combination test for colorectal cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IL264359A IL264359A (en) | 2019-02-28 |
| IL264359B1 IL264359B1 (en) | 2023-11-01 |
| IL264359B2 true IL264359B2 (en) | 2024-03-01 |
Family
ID=56894403
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL264359A IL264359B2 (en) | 2016-07-25 | 2017-07-25 | Combination test for colorectal cancer |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20200182875A1 (https=) |
| EP (1) | EP3488238B1 (https=) |
| JP (1) | JP6983221B2 (https=) |
| KR (1) | KR102442803B1 (https=) |
| CN (1) | CN109791154A (https=) |
| AU (1) | AU2017301970B2 (https=) |
| BR (1) | BR112019001384A2 (https=) |
| CA (1) | CA3031580A1 (https=) |
| GB (1) | GB201612815D0 (https=) |
| IL (1) | IL264359B2 (https=) |
| MY (1) | MY193895A (https=) |
| RU (1) | RU2019104870A (https=) |
| SG (2) | SG10202100630SA (https=) |
| TW (1) | TWI776816B (https=) |
| WO (1) | WO2018019827A1 (https=) |
| ZA (1) | ZA201808601B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201906199D0 (en) * | 2019-05-02 | 2019-06-19 | Belgian Volition Sprl | Method for the detection of cancer |
| WO2021024009A1 (en) * | 2019-08-02 | 2021-02-11 | Shanghai Yunxiang Medical Technology Co., Ltd. | Methods and compositions for providing colon cancer assessment using protein biomarkers |
| CN112345766B (zh) * | 2020-10-22 | 2024-02-02 | 中国工程物理研究院核物理与化学研究所 | 一种荧光-放射性联用的体外靶向筛选方法 |
| TW202242146A (zh) * | 2021-01-13 | 2022-11-01 | 比利時商比利時意志有限公司 | 肺癌的檢測方法 |
| EP4291899A1 (en) * | 2021-02-11 | 2023-12-20 | EDP Biotech Corporation | Kits and methods for detecting markers and determining the presence or risk of cancer |
| WO2024223947A1 (en) * | 2023-04-28 | 2024-10-31 | Belgian Volition Srl | Use of cell free nucleosomes as biomarkers of carcinomas |
| CN116973572B (zh) * | 2023-06-02 | 2025-03-07 | 东南大学附属中大医院 | 基于血、粪便铁蛋白检测评估肠屏障损伤严重程度的方法 |
| CN116718775B (zh) * | 2023-08-04 | 2023-10-27 | 天津迈基生物科技有限公司 | 一种检测结直肠癌的组合物、试纸及方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013030579A1 (en) * | 2011-09-01 | 2013-03-07 | Singapore Volition Pte Limited | Method for detecting nucleosomes containing histone variants |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2541178T3 (es) * | 2009-02-03 | 2015-07-16 | Mdxhealth Sa | Método de detección de cáncer colorrectal |
| WO2010120942A2 (en) * | 2009-04-14 | 2010-10-21 | The Regents Of The University Of California | Histone modification patterns for clinical diagnosis and prognosis of cancer |
| US8568984B2 (en) * | 2010-02-19 | 2013-10-29 | Philadelphia Health & Education Corporation | Methods of diagnosing non-urinary tract diseases by detecting aberrant methylation |
| JP2012018119A (ja) * | 2010-07-09 | 2012-01-26 | Toray Ind Inc | 大腸癌検出用マーカーおよびそれを用いた大腸癌検出方法 |
| CN103328500B (zh) * | 2010-08-04 | 2018-01-26 | 西兹尔生物技术有限公司 | 用于癌症的诊断和治疗的方法和化合物 |
| PT2788767T (pt) * | 2011-12-07 | 2017-12-06 | Belgian Volition Sprl | Método de detecção de adutos de nucleosoma |
| EP4001436B1 (en) * | 2012-05-11 | 2024-03-13 | Clinical Genomics Pty. Ltd. | Diagnostic gene marker panel |
-
2016
- 2016-07-25 GB GBGB1612815.9A patent/GB201612815D0/en not_active Ceased
-
2017
- 2017-07-25 RU RU2019104870A patent/RU2019104870A/ru unknown
- 2017-07-25 MY MYPI2019000398A patent/MY193895A/en unknown
- 2017-07-25 WO PCT/EP2017/068754 patent/WO2018019827A1/en not_active Ceased
- 2017-07-25 BR BR112019001384-9A patent/BR112019001384A2/pt not_active Application Discontinuation
- 2017-07-25 IL IL264359A patent/IL264359B2/en unknown
- 2017-07-25 TW TW106124811A patent/TWI776816B/zh active
- 2017-07-25 SG SG10202100630SA patent/SG10202100630SA/en unknown
- 2017-07-25 JP JP2019503672A patent/JP6983221B2/ja active Active
- 2017-07-25 SG SG11201900329XA patent/SG11201900329XA/en unknown
- 2017-07-25 CN CN201780045694.2A patent/CN109791154A/zh active Pending
- 2017-07-25 KR KR1020197002048A patent/KR102442803B1/ko active Active
- 2017-07-25 CA CA3031580A patent/CA3031580A1/en active Pending
- 2017-07-25 US US16/320,440 patent/US20200182875A1/en not_active Abandoned
- 2017-07-25 AU AU2017301970A patent/AU2017301970B2/en not_active Ceased
- 2017-07-25 EP EP17743043.6A patent/EP3488238B1/en active Active
-
2018
- 2018-12-20 ZA ZA2018/08601A patent/ZA201808601B/en unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013030579A1 (en) * | 2011-09-01 | 2013-03-07 | Singapore Volition Pte Limited | Method for detecting nucleosomes containing histone variants |
Non-Patent Citations (3)
| Title |
|---|
| AL-SHUNEIGAT J.M. ET AL.,, COLORECTAL CARCINOMA: NUCLEOSOMES, CARCINOEMBRYONIC ANTIGEN AND CA 19-9 AS APOPTOTIC MARKERS; A COMPARATIVE STUDY, 25 July 2011 (2011-07-25) * |
| HOLDENRIEDER S. ET AL.,, NOVEL SERUM NUCLEOSOMICS BIOMARKERS FOR THE DETECTION OF COLORECTAL CANCER, 31 May 2014 (2014-05-31) * |
| KARL J. ET AL.,, IMPROVED DIAGNOSIS OF COLORECTAL CANCER USING A COMBINATION OF FECAL OCCULT BLOOD AND NOVEL FECAL PROTEIN MARKERS, 31 October 2008 (2008-10-31) * |
Also Published As
| Publication number | Publication date |
|---|---|
| MY193895A (en) | 2022-10-31 |
| EP3488238B1 (en) | 2023-06-07 |
| TW201804156A (zh) | 2018-02-01 |
| TWI776816B (zh) | 2022-09-11 |
| IL264359B1 (en) | 2023-11-01 |
| AU2017301970A1 (en) | 2019-01-17 |
| KR102442803B1 (ko) | 2022-09-15 |
| JP6983221B2 (ja) | 2021-12-17 |
| CN109791154A (zh) | 2019-05-21 |
| BR112019001384A2 (pt) | 2019-04-30 |
| US20200182875A1 (en) | 2020-06-11 |
| RU2019104870A (ru) | 2020-08-25 |
| IL264359A (en) | 2019-02-28 |
| EP3488238A1 (en) | 2019-05-29 |
| ZA201808601B (en) | 2019-09-25 |
| WO2018019827A1 (en) | 2018-02-01 |
| GB201612815D0 (en) | 2016-09-07 |
| EP3488238C0 (en) | 2023-06-07 |
| JP2019527361A (ja) | 2019-09-26 |
| SG11201900329XA (en) | 2019-02-27 |
| KR20190039089A (ko) | 2019-04-10 |
| AU2017301970B2 (en) | 2023-04-27 |
| RU2019104870A3 (https=) | 2020-12-01 |
| SG10202100630SA (en) | 2021-03-30 |
| CA3031580A1 (en) | 2018-02-01 |
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