IL262494A - תכשיר צירוף רוקחות המכיל הרכבי קומפלקסים של איבקפטור ולומאקפטור מלחיהם ותולדותיהם, תהליך להכנתם ותכשירי רוקחות המכילים אותם - Google Patents

תכשיר צירוף רוקחות המכיל הרכבי קומפלקסים של איבקפטור ולומאקפטור מלחיהם ותולדותיהם, תהליך להכנתם ותכשירי רוקחות המכילים אותם

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Publication number
IL262494A
IL262494A IL262494A IL26249418A IL262494A IL 262494 A IL262494 A IL 262494A IL 262494 A IL262494 A IL 262494A IL 26249418 A IL26249418 A IL 26249418A IL 262494 A IL262494 A IL 262494A
Authority
IL
Israel
Prior art keywords
lumacaftor
ivacaftor
derivatives
salts
preparation
Prior art date
Application number
IL262494A
Other languages
English (en)
Original Assignee
Druggability Tech Ip Holdco Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Druggability Tech Ip Holdco Ltd filed Critical Druggability Tech Ip Holdco Ltd
Publication of IL262494A publication Critical patent/IL262494A/he

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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IL262494A 2016-04-25 2018-10-21 תכשיר צירוף רוקחות המכיל הרכבי קומפלקסים של איבקפטור ולומאקפטור מלחיהם ותולדותיהם, תהליך להכנתם ותכשירי רוקחות המכילים אותם IL262494A (he)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU1600271A HUP1600271A2 (hu) 2016-04-25 2016-04-25 Ivacaftor és Lumacaftor sóinak és származékainak komplexei, eljárás azok elõállítására és azok gyógyszerészetileg elfogadható készítményei
PCT/IB2017/052374 WO2017187340A1 (en) 2016-04-25 2017-04-25 Pharmaceutical combination composition comprising complex formulations of ivacaftor and lumacaftor and their salts and derivatives, process for their preparation thereof and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
IL262494A true IL262494A (he) 2018-12-31

Family

ID=89992149

Family Applications (1)

Application Number Title Priority Date Filing Date
IL262494A IL262494A (he) 2016-04-25 2018-10-21 תכשיר צירוף רוקחות המכיל הרכבי קומפלקסים של איבקפטור ולומאקפטור מלחיהם ותולדותיהם, תהליך להכנתם ותכשירי רוקחות המכילים אותם

Country Status (8)

Country Link
EP (1) EP3448384A1 (he)
JP (1) JP2019514898A (he)
CN (1) CN109475546A (he)
AU (1) AU2017256184A1 (he)
CA (1) CA3022203A1 (he)
HU (1) HUP1600271A2 (he)
IL (1) IL262494A (he)
WO (1) WO2017187340A1 (he)

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US10898484B2 (en) 2018-05-31 2021-01-26 Celltaxis, Llc Method of reducing pulmonary exacerbations in respiratory disease patients
EP3968955B1 (en) * 2019-04-18 2025-08-27 Kinedexe UK Limited Pharmaceutical oral liquid solution of ivacaftor
WO2023044365A1 (en) * 2021-09-17 2023-03-23 Doublerainbow Biosciences Inc. Use of cyclodextrin to enhance solubility of substrates and increase enzymatic glycosylation reaction efficiency
CN118949037B (zh) * 2024-08-05 2025-10-17 江苏百奥信康医药科技有限公司 用于治疗IgG4相关性疾病的CFTR调节剂

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US8354427B2 (en) 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
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