IL258567B2 - A composition comprising a colloidal particle for use in the treatment of haemophilia a, a kit comprising threof and a dosage form threof - Google Patents
A composition comprising a colloidal particle for use in the treatment of haemophilia a, a kit comprising threof and a dosage form threofInfo
- Publication number
- IL258567B2 IL258567B2 IL258567A IL25856718A IL258567B2 IL 258567 B2 IL258567 B2 IL 258567B2 IL 258567 A IL258567 A IL 258567A IL 25856718 A IL25856718 A IL 25856718A IL 258567 B2 IL258567 B2 IL 258567B2
- Authority
- IL
- Israel
- Prior art keywords
- composition
- amphipathic lipid
- glycero
- dspe
- factor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1518172.0A GB201518172D0 (en) | 2015-10-14 | 2015-10-14 | Colloidal particles for use in medicine |
| PCT/EP2016/074759 WO2017064276A1 (en) | 2015-10-14 | 2016-10-14 | Colloidal particles for use in medicine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IL258567A IL258567A (en) | 2018-05-31 |
| IL258567B1 IL258567B1 (en) | 2025-04-01 |
| IL258567B2 true IL258567B2 (en) | 2025-08-01 |
Family
ID=55131025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL258567A IL258567B2 (en) | 2015-10-14 | 2016-10-14 | A composition comprising a colloidal particle for use in the treatment of haemophilia a, a kit comprising threof and a dosage form threof |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20190192664A1 (enExample) |
| EP (1) | EP3362039A1 (enExample) |
| JP (1) | JP7160678B2 (enExample) |
| KR (1) | KR20180067616A (enExample) |
| CN (1) | CN108472246A (enExample) |
| AU (1) | AU2016336929B2 (enExample) |
| BR (1) | BR112018007399A2 (enExample) |
| CA (1) | CA3036111C (enExample) |
| EA (1) | EA201890703A1 (enExample) |
| GB (1) | GB201518172D0 (enExample) |
| HK (1) | HK1256814A1 (enExample) |
| IL (1) | IL258567B2 (enExample) |
| MX (1) | MX391574B (enExample) |
| SG (2) | SG11201802956RA (enExample) |
| WO (1) | WO2017064276A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021092580A1 (en) * | 2019-11-07 | 2021-05-14 | The Board Of Trustees Of The University Of Illinois | Peptides and methods of treating sepsis, atherosclerosis, thrombosis, stroke, heart attack and inflammation |
| GB202111757D0 (en) * | 2021-08-17 | 2021-09-29 | Cantab Biopharmaceuticals Patents Ltd | Modified colloidal particles for use in the treatment of haemophilia A |
| GB202111759D0 (en) * | 2021-08-17 | 2021-09-29 | Cantab Biopharmaceuticals Patents Ltd | Modified colloidal particles |
| GB202111758D0 (en) * | 2021-08-17 | 2021-09-29 | Cantab Biopharmaceuticals Patents Ltd | Modified colloidal particles for use in the treatment of haemophilia A |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070167359A1 (en) * | 2003-04-15 | 2007-07-19 | Moshe Baru | Pharmaceutical composition comprising proteins and/or polypeptides and colloidal particles |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| DE69418334T2 (de) | 1993-08-06 | 2000-01-27 | Opperbas Holding B.V., Amsterdam | Verfahren zur hohen beladung von vesikeln mit biopolymeren substanzen |
| MXPA00010241A (es) | 1998-04-27 | 2004-09-06 | Opperbas Holding Bv | Composicion farmaceutica que comprende el factor viii y liposomas neutrales.. |
| US6294192B1 (en) * | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| RU2250911C2 (ru) | 1999-07-14 | 2005-04-27 | Элзэ Копэрейшн | Липосомальная композиция, нейтральный липополимер и способ увеличения времени циркуляции липосомы |
| US20030232075A1 (en) * | 2002-05-06 | 2003-12-18 | University Of Minnesota, A Minnesota Corporation | Compositions for producing factor Xa |
| JP2008544990A (ja) * | 2005-06-29 | 2008-12-11 | ザ リサーチ ファウンデイション オブ ステイト ユニバーシティー オブ ニューヨーク | 低免疫原性蛋白質−脂質複合体に関する組成物および方法 |
| AU2010255391C1 (en) | 2009-06-03 | 2016-10-27 | Sequessome Technology Holdings Limited | Formulations for the treatment of deep tissue pain |
| MX336482B (es) | 2009-08-21 | 2016-01-21 | Henk-Andre Kroon | Formulaciones vesiculares. |
| GB201007356D0 (en) | 2010-04-30 | 2010-06-16 | Leverton Licence Holdings Ltd | Conjugated factor VIIa |
| GB201007357D0 (en) | 2010-04-30 | 2010-06-16 | Leverton Licence Holdings Ltd | Conjugated factor VIII |
| EP2838566A2 (en) | 2012-04-16 | 2015-02-25 | Cantab Biopharmaceuticals Patents Limited | Optimised subcutaneous therapeutic agents |
| CN107879960B (zh) * | 2013-03-08 | 2021-06-22 | 诺华股份有限公司 | 用于传递活性成分的脂质和脂质组合物 |
-
2015
- 2015-10-14 GB GBGB1518172.0A patent/GB201518172D0/en not_active Ceased
-
2016
- 2016-10-14 CA CA3036111A patent/CA3036111C/en active Active
- 2016-10-14 WO PCT/EP2016/074759 patent/WO2017064276A1/en not_active Ceased
- 2016-10-14 SG SG11201802956RA patent/SG11201802956RA/en unknown
- 2016-10-14 CN CN201680073237.XA patent/CN108472246A/zh active Pending
- 2016-10-14 EA EA201890703A patent/EA201890703A1/ru unknown
- 2016-10-14 IL IL258567A patent/IL258567B2/en unknown
- 2016-10-14 US US15/768,381 patent/US20190192664A1/en not_active Abandoned
- 2016-10-14 MX MX2018004445A patent/MX391574B/es unknown
- 2016-10-14 EP EP16781807.9A patent/EP3362039A1/en active Pending
- 2016-10-14 HK HK18115899.0A patent/HK1256814A1/zh unknown
- 2016-10-14 BR BR112018007399A patent/BR112018007399A2/pt not_active Application Discontinuation
- 2016-10-14 KR KR1020187013254A patent/KR20180067616A/ko not_active Ceased
- 2016-10-14 SG SG10202010711UA patent/SG10202010711UA/en unknown
- 2016-10-14 JP JP2018519423A patent/JP7160678B2/ja active Active
- 2016-10-14 AU AU2016336929A patent/AU2016336929B2/en not_active Ceased
-
2020
- 2020-05-26 US US16/883,338 patent/US20210093721A1/en not_active Abandoned
-
2024
- 2024-06-24 US US18/752,365 patent/US20250170244A1/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070167359A1 (en) * | 2003-04-15 | 2007-07-19 | Moshe Baru | Pharmaceutical composition comprising proteins and/or polypeptides and colloidal particles |
Also Published As
| Publication number | Publication date |
|---|---|
| SG10202010711UA (en) | 2020-12-30 |
| EP3362039A1 (en) | 2018-08-22 |
| CN108472246A (zh) | 2018-08-31 |
| AU2016336929B2 (en) | 2022-09-29 |
| IL258567B1 (en) | 2025-04-01 |
| WO2017064276A1 (en) | 2017-04-20 |
| CA3036111C (en) | 2023-06-06 |
| HK1256814A1 (zh) | 2019-10-04 |
| EA201890703A1 (ru) | 2018-11-30 |
| MX2018004445A (es) | 2018-08-14 |
| MX391574B (es) | 2025-03-21 |
| US20250170244A1 (en) | 2025-05-29 |
| SG11201802956RA (en) | 2018-05-30 |
| IL258567A (en) | 2018-05-31 |
| JP7160678B2 (ja) | 2022-10-25 |
| BR112018007399A2 (pt) | 2018-10-16 |
| AU2016336929A1 (en) | 2018-05-10 |
| CA3036111A1 (en) | 2017-04-20 |
| US20190192664A1 (en) | 2019-06-27 |
| US20210093721A1 (en) | 2021-04-01 |
| JP2018535952A (ja) | 2018-12-06 |
| GB201518172D0 (en) | 2015-11-25 |
| KR20180067616A (ko) | 2018-06-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US20250170244A1 (en) | Colloidal particles for use in medicine | |
| JP7573582B2 (ja) | Ｐｅｇ化リポソームおよび血液凝固因子の製剤処方 | |
| WO2017064289A1 (en) | Colloidal particles for topical administration with therapeutic agent | |
| KR20240040125A (ko) | A형 혈우병 치료용 변형된 콜로이드 입자 | |
| WO2017064300A1 (en) | Colloidal particles for subcutaneous administration with intravenous administration of therapeutic agent | |
| US20240358801A1 (en) | Modified colloidal particles for use in the treatment of haemophilia a | |
| US20250064738A1 (en) | Modified colloidal particles for use in the treatment of haemophilia a |