IL256912B2 - Methods of treating developmental disorders with gaboxadol - Google Patents

Methods of treating developmental disorders with gaboxadol

Info

Publication number
IL256912B2
IL256912B2 IL256912A IL25691218A IL256912B2 IL 256912 B2 IL256912 B2 IL 256912B2 IL 256912 A IL256912 A IL 256912A IL 25691218 A IL25691218 A IL 25691218A IL 256912 B2 IL256912 B2 IL 256912B2
Authority
IL
Israel
Prior art keywords
gaboxadol
patient
pharmaceutical composition
pharmaceutically acceptable
hours
Prior art date
Application number
IL256912A
Other languages
English (en)
Hebrew (he)
Other versions
IL256912A (en
IL256912B1 (en
Original Assignee
Ovid Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ovid Therapeutics Inc filed Critical Ovid Therapeutics Inc
Publication of IL256912A publication Critical patent/IL256912A/en
Publication of IL256912B1 publication Critical patent/IL256912B1/en
Publication of IL256912B2 publication Critical patent/IL256912B2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL256912A 2015-07-17 2016-07-14 Methods of treating developmental disorders with gaboxadol IL256912B2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562193717P 2015-07-17 2015-07-17
US201562207595P 2015-08-20 2015-08-20
US201662332567P 2016-05-06 2016-05-06
US201662346763P 2016-06-07 2016-06-07
US15/209,862 US20170014393A1 (en) 2015-07-17 2016-07-14 Methods of treating developmental disorders with gaboxadol
PCT/US2016/042238 WO2017015049A1 (en) 2015-07-17 2016-07-14 Methods of treating developmental disorders with gaboxadol

Publications (3)

Publication Number Publication Date
IL256912A IL256912A (en) 2018-03-29
IL256912B1 IL256912B1 (en) 2023-09-01
IL256912B2 true IL256912B2 (en) 2024-01-01

Family

ID=57774846

Family Applications (2)

Application Number Title Priority Date Filing Date
IL256912A IL256912B2 (en) 2015-07-17 2016-07-14 Methods of treating developmental disorders with gaboxadol
IL305342A IL305342A (en) 2015-07-17 2016-07-14 Methods for treating developmental disorders with gaboxadol

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL305342A IL305342A (en) 2015-07-17 2016-07-14 Methods for treating developmental disorders with gaboxadol

Country Status (17)

Country Link
US (8) US20170014393A1 (OSRAM)
EP (2) EP4541420A3 (OSRAM)
JP (3) JP2018520189A (OSRAM)
KR (2) KR20180031721A (OSRAM)
CN (2) CN108024997A (OSRAM)
AU (2) AU2016295138B2 (OSRAM)
BR (1) BR112018000933A2 (OSRAM)
CA (1) CA2992734A1 (OSRAM)
CL (1) CL2018000142A1 (OSRAM)
CO (1) CO2018000375A2 (OSRAM)
ES (1) ES3021189T3 (OSRAM)
HK (1) HK1250951A1 (OSRAM)
IL (2) IL256912B2 (OSRAM)
MX (2) MX391708B (OSRAM)
PE (2) PE20190338A1 (OSRAM)
TW (2) TWI819995B (OSRAM)
WO (1) WO2017015049A1 (OSRAM)

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RS62006B1 (sr) 2014-06-06 2021-07-30 Ovid Therapeutics Inc Postupci pojačavanja tonične inhibicije i lečenja sekundarne nesanice
MX391708B (es) 2015-07-17 2025-03-21 Ovid Therapeutics Inc Metodos para tratar trastornos del desarrollo con gaboxadol.
KR102518846B1 (ko) 2016-08-11 2023-04-05 오비드 테라퓨틱스 인크. 간질 장애의 치료를 위한 방법 및 조성물
JP2019535760A (ja) * 2016-11-22 2019-12-12 オービッド・セラピューティクス・インコーポレイテッドＯｖｉｄ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． フルピルチンを用いた発達障害および／または発作性障害の処置方法
US10071083B2 (en) * 2017-02-03 2018-09-11 Ovid Therapeutics Inc Use of gaboxadol in the treatment of tinnitus
US20180338959A1 (en) * 2017-05-24 2018-11-29 Ovid Therapeutics Inc. Treatment of depressive disorders
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EP3711761A4 (en) * 2017-11-14 2021-11-24 SK Biopharmaceuticals Co., Ltd. USE OF A CARBAMATE COMPOUND TO REDUCE OR TREAT DEVELOPMENTAL DISORDERS, INCLUDING FRAGILE X SYNDROME, ANGELMAN'S SYNDROME, OR RETT'S SYNDROME
US10704048B2 (en) 2018-06-14 2020-07-07 Ovid Therapeutics Inc. Use of MIR-92A or MIR-145 in the treatment of Angelman syndrome
WO2020041574A1 (en) * 2018-08-22 2020-02-27 Ovid Therapeutics Inc. Use of gaboxadol in the treatment of gastrointestinal tract disorders and asthma
EP3833351A4 (en) * 2018-09-20 2021-10-13 Ovid Therapeutics Inc. USE OF GABOXADOL FOR THE TREATMENT OF GILLES DE LA TOURETTE SYNDROME, TICS AND STATTING
JP2022511755A (ja) * 2018-11-21 2022-02-01 セルテゴ セラピューティクス インコーポレイテッド 精神障害の治療のためのガボキサドールとリチウムとの組み合わせ
BR112021009944A2 (pt) 2018-11-21 2021-08-17 Certego Therapeutics Inc. gaboxadol para reduzir risco de suicídio e alívio rápido de depressão
KR20210105387A (ko) 2018-12-17 2021-08-26 오비드 테라퓨틱스 인크. 비-24 시간 수면-각성 장애의 치료를 위한 가복사돌의 사용
WO2020247127A1 (en) * 2019-06-07 2020-12-10 Paxmedica, Inc. Compositions and methods for treating central nervous system disorders
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AU2020405060A1 (en) * 2019-12-18 2022-06-09 Ovid Therapeutics Inc. Gaboxadol for therapeutic treatment of 1p36 deletion syndrome
JP2023526439A (ja) 2020-05-20 2023-06-21 セルテゴ セラピューティクス インコーポレイテッド 精神障害の処置のための環重水素化ガボキサドールおよびその使用

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Also Published As

Publication number Publication date
US20190117632A1 (en) 2019-04-25
CN108024997A (zh) 2018-05-11
CA2992734A1 (en) 2017-01-26
PE20230735A1 (es) 2023-05-03
TW201707700A (zh) 2017-03-01
CN116531370A (zh) 2023-08-04
JP2021130687A (ja) 2021-09-09
EP4541420A2 (en) 2025-04-23
BR112018000933A2 (pt) 2018-09-04
AU2021250862B2 (en) 2023-11-09
US20170014393A1 (en) 2017-01-19
TWI819995B (zh) 2023-11-01
HK1250951A1 (zh) 2019-01-18
IL256912A (en) 2018-03-29
US20180338960A1 (en) 2018-11-29
IL256912B1 (en) 2023-09-01
EP4541420A3 (en) 2025-06-25
MX391708B (es) 2025-03-21
AU2016295138A1 (en) 2018-02-08
US20180098974A1 (en) 2018-04-12
CL2018000142A1 (es) 2018-07-13
ES3021189T3 (en) 2025-05-26
IL305342A (en) 2023-10-01
TW202325293A (zh) 2023-07-01
KR20240160666A (ko) 2024-11-11
US20190255027A1 (en) 2019-08-22
US12465597B2 (en) 2025-11-11
JP2018520189A (ja) 2018-07-26
AU2021250862A1 (en) 2021-11-04
EP3324961C0 (en) 2025-03-19
CO2018000375A2 (es) 2018-04-19
US11096929B2 (en) 2021-08-24
US20190321342A1 (en) 2019-10-24
WO2017015049A1 (en) 2017-01-26
MX2018000745A (es) 2018-08-15
AU2016295138B2 (en) 2021-11-04
EP3324961B1 (en) 2025-03-19
PE20190338A1 (es) 2019-03-07
EP3324961A1 (en) 2018-05-30
EP3324961A4 (en) 2019-03-13
MX2022004734A (es) 2022-05-13
JP2023103375A (ja) 2023-07-26
US20210030727A1 (en) 2021-02-04
US20230071127A1 (en) 2023-03-09
KR20180031721A (ko) 2018-03-28

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