CO2018000375A2 - Métodos para el tratamiento de trastornos de desarrollo con gaboxadol - Google Patents
Métodos para el tratamiento de trastornos de desarrollo con gaboxadolInfo
- Publication number
- CO2018000375A2 CO2018000375A2 CONC2018/0000375A CO2018000375A CO2018000375A2 CO 2018000375 A2 CO2018000375 A2 CO 2018000375A2 CO 2018000375 A CO2018000375 A CO 2018000375A CO 2018000375 A2 CO2018000375 A2 CO 2018000375A2
- Authority
- CO
- Colombia
- Prior art keywords
- gaboxadol
- patient
- acceptable salt
- syndrome
- pharmaceutically acceptable
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 12
- ZXRVKCBLGJOCEE-UHFFFAOYSA-N Gaboxadol Chemical compound C1NCCC2=C1ONC2=O ZXRVKCBLGJOCEE-UHFFFAOYSA-N 0.000 title abstract 9
- 229950004346 gaboxadol Drugs 0.000 title abstract 9
- 208000012239 Developmental disease Diseases 0.000 title abstract 7
- 150000003839 salts Chemical class 0.000 abstract 8
- 239000008194 pharmaceutical composition Substances 0.000 abstract 4
- 238000001727 in vivo Methods 0.000 abstract 3
- 208000029560 autism spectrum disease Diseases 0.000 abstract 2
- 201000003415 fragile X-associated tremor/ataxia syndrome Diseases 0.000 abstract 2
- 208000011580 syndromic disease Diseases 0.000 abstract 2
- 208000036640 Asperger disease Diseases 0.000 abstract 1
- 201000006062 Asperger syndrome Diseases 0.000 abstract 1
- 206010003805 Autism Diseases 0.000 abstract 1
- 208000020706 Autistic disease Diseases 0.000 abstract 1
- 208000001914 Fragile X syndrome Diseases 0.000 abstract 1
- 208000012202 Pervasive developmental disease Diseases 0.000 abstract 1
- 201000010769 Prader-Willi syndrome Diseases 0.000 abstract 1
- 208000006289 Rett Syndrome Diseases 0.000 abstract 1
- 206010043118 Tardive Dyskinesia Diseases 0.000 abstract 1
- 206010049644 Williams syndrome Diseases 0.000 abstract 1
- 208000024825 childhood disintegrative disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562193717P | 2015-07-17 | 2015-07-17 | |
| US201562207595P | 2015-08-20 | 2015-08-20 | |
| US201662332567P | 2016-05-06 | 2016-05-06 | |
| US201662346763P | 2016-06-07 | 2016-06-07 | |
| PCT/US2016/042238 WO2017015049A1 (en) | 2015-07-17 | 2016-07-14 | Methods of treating developmental disorders with gaboxadol |
| US15/209,862 US20170014393A1 (en) | 2015-07-17 | 2016-07-14 | Methods of treating developmental disorders with gaboxadol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO2018000375A2 true CO2018000375A2 (es) | 2018-04-19 |
Family
ID=57774846
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CONC2018/0000375A CO2018000375A2 (es) | 2015-07-17 | 2018-01-22 | Métodos para el tratamiento de trastornos de desarrollo con gaboxadol |
Country Status (17)
| Country | Link |
|---|---|
| US (8) | US20170014393A1 (OSRAM) |
| EP (2) | EP4541420A3 (OSRAM) |
| JP (3) | JP2018520189A (OSRAM) |
| KR (2) | KR20240160666A (OSRAM) |
| CN (2) | CN116531370A (OSRAM) |
| AU (2) | AU2016295138B2 (OSRAM) |
| BR (1) | BR112018000933A2 (OSRAM) |
| CA (1) | CA2992734A1 (OSRAM) |
| CL (1) | CL2018000142A1 (OSRAM) |
| CO (1) | CO2018000375A2 (OSRAM) |
| ES (1) | ES3021189T3 (OSRAM) |
| HK (1) | HK1250951A1 (OSRAM) |
| IL (2) | IL305342A (OSRAM) |
| MX (2) | MX391708B (OSRAM) |
| PE (2) | PE20190338A1 (OSRAM) |
| TW (2) | TWI819995B (OSRAM) |
| WO (1) | WO2017015049A1 (OSRAM) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3151832T (pt) * | 2014-06-06 | 2021-06-15 | Ovid Therapeutics Inc | Métodos para aumentar a inibição tónica e tratar a insónia secundária |
| AU2016295138B2 (en) | 2015-07-17 | 2021-11-04 | Ovid Therapeutics Inc. | Methods of treating developmental disorders with gaboxadol |
| US20180042903A1 (en) | 2016-08-11 | 2018-02-15 | Ovid Therapeutics Inc. | Methods and compositions for treatment of epileptic disorders |
| CN110225754A (zh) * | 2016-11-22 | 2019-09-10 | 奥维德医疗公司 | 用氟吡汀治疗发育障碍和/或癫痫发作紊乱的方法 |
| US10071083B2 (en) * | 2017-02-03 | 2018-09-11 | Ovid Therapeutics Inc | Use of gaboxadol in the treatment of tinnitus |
| US20180338959A1 (en) * | 2017-05-24 | 2018-11-29 | Ovid Therapeutics Inc. | Treatment of depressive disorders |
| CA3071939A1 (en) | 2017-08-04 | 2019-02-07 | Ovid Therapeutics Inc. | Use of gaboxadol in the treatment of diabetes and related conditions |
| CN111432814B (zh) * | 2017-11-14 | 2024-05-14 | 爱思开生物制药株式会社 | 用于减轻或治疗包括脆性X染色体综合征、Angelman综合征或Rett综合征的发育障碍的氨基甲酸酯化合物的用途 |
| CN112739353A (zh) * | 2018-06-14 | 2021-04-30 | 奥维德医疗公司 | Mir-92a或mir-145在治疗安格曼综合征中的用途 |
| EP3823619A4 (en) * | 2018-08-22 | 2021-11-17 | Ovid Therapeutics Inc. | USE OF GABOXADOL FOR TREATMENT OF GIOMETAL TRACT DISORDERS AND ASTHMA |
| WO2020061410A1 (en) * | 2018-09-20 | 2020-03-26 | Ovid Therapeutics Inc. | Use of gaboxadol for the treatment of tourette syndrome, tics and stuttering |
| CN114072154B (zh) * | 2018-11-21 | 2024-03-08 | 塞迪戈Abc有限责任公司 | 用于治疗精神障碍的加波沙朵和锂的组合物 |
| MX2021005992A (es) | 2018-11-21 | 2021-09-14 | Certego Therapeutics Inc | Gaboxadol para reducir el riesgo de suicidio y para alivio rápido de la depresión. |
| JP2022514275A (ja) | 2018-12-17 | 2022-02-10 | オービッド・セラピューティクス・インコーポレイテッド | 非２４時間型睡眠覚醒障害の処置のためのガボキサドールの使用 |
| WO2020247127A1 (en) * | 2019-06-07 | 2020-12-10 | Paxmedica, Inc. | Compositions and methods for treating central nervous system disorders |
| JP2022540917A (ja) * | 2019-07-15 | 2022-09-20 | オービッド・セラピューティクス・インコーポレイテッド | 治療的処置のためのガボキサドール含有医薬製剤 |
| MX2022007715A (es) * | 2019-12-18 | 2022-07-19 | Ovid Therapeutics Inc | Gaboxadol para el tratamiento terapeutico del sindrome de delecion 1p36. |
| IL298334A (en) | 2020-05-20 | 2023-01-01 | Certego Therapeutics Inc | Ring deuterated gaboxadol and its use for the treatment of psychiatric disorders |
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| PT3151832T (pt) * | 2014-06-06 | 2021-06-15 | Ovid Therapeutics Inc | Métodos para aumentar a inibição tónica e tratar a insónia secundária |
| JP6491679B2 (ja) | 2014-06-12 | 2019-03-27 | ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ | Ｇａｂａａ受容体活性のモジュレーターとしてのイミダゾピリダジン誘導体 |
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| AU2016295138B2 (en) | 2015-07-17 | 2021-11-04 | Ovid Therapeutics Inc. | Methods of treating developmental disorders with gaboxadol |
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| US20180042903A1 (en) | 2016-08-11 | 2018-02-15 | Ovid Therapeutics Inc. | Methods and compositions for treatment of epileptic disorders |
| CN110225754A (zh) | 2016-11-22 | 2019-09-10 | 奥维德医疗公司 | 用氟吡汀治疗发育障碍和/或癫痫发作紊乱的方法 |
| US10071083B2 (en) | 2017-02-03 | 2018-09-11 | Ovid Therapeutics Inc | Use of gaboxadol in the treatment of tinnitus |
-
2016
- 2016-07-14 AU AU2016295138A patent/AU2016295138B2/en active Active
- 2016-07-14 US US15/209,862 patent/US20170014393A1/en not_active Abandoned
- 2016-07-14 EP EP25162297.3A patent/EP4541420A3/en active Pending
- 2016-07-14 ES ES16828266T patent/ES3021189T3/es active Active
- 2016-07-14 BR BR112018000933A patent/BR112018000933A2/pt not_active Application Discontinuation
- 2016-07-14 KR KR1020247036072A patent/KR20240160666A/ko not_active Ceased
- 2016-07-14 HK HK18110494.0A patent/HK1250951A1/zh unknown
- 2016-07-14 IL IL305342A patent/IL305342A/en unknown
- 2016-07-14 MX MX2018000745A patent/MX391708B/es unknown
- 2016-07-14 CN CN202310549878.XA patent/CN116531370A/zh active Pending
- 2016-07-14 CA CA2992734A patent/CA2992734A1/en active Pending
- 2016-07-14 JP JP2018502084A patent/JP2018520189A/ja not_active Withdrawn
- 2016-07-14 KR KR1020187004863A patent/KR20180031721A/ko not_active Ceased
- 2016-07-14 PE PE2018000085A patent/PE20190338A1/es unknown
- 2016-07-14 PE PE2022002752A patent/PE20230735A1/es unknown
- 2016-07-14 IL IL256912A patent/IL256912B2/en unknown
- 2016-07-14 CN CN201680054308.1A patent/CN108024997A/zh active Pending
- 2016-07-14 WO PCT/US2016/042238 patent/WO2017015049A1/en not_active Ceased
- 2016-07-14 EP EP16828266.3A patent/EP3324961B1/en active Active
- 2016-07-15 TW TW105122538A patent/TWI819995B/zh active
- 2016-07-15 TW TW112110413A patent/TW202325293A/zh unknown
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2017
- 2017-12-13 US US15/840,521 patent/US20180098974A1/en not_active Abandoned
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2018
- 2018-01-17 CL CL2018000142A patent/CL2018000142A1/es unknown
- 2018-01-17 MX MX2022004734A patent/MX2022004734A/es unknown
- 2018-01-22 CO CONC2018/0000375A patent/CO2018000375A2/es unknown
- 2018-08-02 US US16/053,343 patent/US20180338960A1/en not_active Abandoned
- 2018-12-17 US US16/221,794 patent/US11096929B2/en active Active
-
2019
- 2019-05-01 US US16/400,227 patent/US20190255027A1/en not_active Abandoned
- 2019-06-25 US US16/451,591 patent/US20190321342A1/en not_active Abandoned
-
2020
- 2020-06-25 US US16/911,540 patent/US20210030727A1/en not_active Abandoned
-
2021
- 2021-05-25 JP JP2021087584A patent/JP2021130687A/ja active Pending
- 2021-10-12 AU AU2021250862A patent/AU2021250862B2/en active Active
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2022
- 2022-11-04 US US17/981,148 patent/US12465597B2/en active Active
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2023
- 2023-05-16 JP JP2023080696A patent/JP2023103375A/ja active Pending
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