IL255351A0 - Astrocyte biomarkers of trauma and neurotrauma - Google Patents

Astrocyte biomarkers of trauma and neurotrauma

Info

Publication number
IL255351A0
IL255351A0 IL255351A IL25535117A IL255351A0 IL 255351 A0 IL255351 A0 IL 255351A0 IL 255351 A IL255351 A IL 255351A IL 25535117 A IL25535117 A IL 25535117A IL 255351 A0 IL255351 A0 IL 255351A0
Authority
IL
Israel
Prior art keywords
traumatome
astrocyte
neurotrauma
biomarkers
neurotrauma biomarkers
Prior art date
Application number
IL255351A
Other languages
English (en)
Hebrew (he)
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of IL255351A0 publication Critical patent/IL255351A0/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y201/00Transferases transferring one-carbon groups (2.1)
    • C12Y201/01Methyltransferases (2.1.1)
    • C12Y201/01259[Fructose-bisphosphate aldolase]-lysine N-methyltransferase (2.1.1.259)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/2871Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/40Disorders due to exposure to physical agents, e.g. heat disorders, motion sickness, radiation injuries, altitude sickness, decompression illness
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL255351A 2015-05-05 2017-10-31 Astrocyte biomarkers of trauma and neurotrauma IL255351A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562157389P 2015-05-05 2015-05-05
PCT/US2016/031043 WO2016179426A1 (en) 2015-05-05 2016-05-05 Astrocyte traumatome and neurotrauma biomarkers

Publications (1)

Publication Number Publication Date
IL255351A0 true IL255351A0 (en) 2017-12-31

Family

ID=57218432

Family Applications (1)

Application Number Title Priority Date Filing Date
IL255351A IL255351A0 (en) 2015-05-05 2017-10-31 Astrocyte biomarkers of trauma and neurotrauma

Country Status (7)

Country Link
US (4) US10557859B2 (enExample)
EP (1) EP3292414B1 (enExample)
JP (1) JP6839854B2 (enExample)
CN (1) CN107864671A (enExample)
ES (1) ES2873509T3 (enExample)
IL (1) IL255351A0 (enExample)
WO (1) WO2016179426A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107864671A (zh) * 2015-05-05 2018-03-30 加利福尼亚大学董事会 星形细胞创伤节和神经创伤生物标志物
WO2018217792A1 (en) * 2017-05-23 2018-11-29 Immunarray USA, Inc. Biomarker levels and neuroimaging for detecting, monitoring and treating brain injury or trauma
WO2019099732A1 (en) * 2017-11-16 2019-05-23 Brainbox Solutions, Inc. Protein biomarker indicators of neurological injury and/or disease and methods of use thereof
CN111699391A (zh) 2017-12-29 2020-09-22 雅培实验室 用于诊断和评估创伤性脑损伤的新型生物标志物和方法
EP4053559A1 (en) * 2021-03-01 2022-09-07 Consorcio Centro de Investigación Biomédica en Red, M.P. (CIBER) Methods for the measurement of protein c and activated protein c
WO2026068747A1 (en) * 2024-09-26 2026-04-02 Centre Hospitalier Universitaire Vaudois (C.H.U.V.) Astrocytic phosphoprotein (pea-15) for use in the treatment and/or prevention of a neuronal disorder

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8492107B2 (en) * 2004-04-15 2013-07-23 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for nervous system injury and other neural disorders
GB0414798D0 (en) * 2004-07-01 2004-08-04 Paradigm Therapeutics Ltd Receptor
WO2007136617A2 (en) * 2006-05-18 2007-11-29 Walter Reed Army Institute Of Research (Wrair) Endothelial-monocyte activating polypeptide ii, a biomarker for use in diagnosis of brain injury
WO2009100131A2 (en) * 2008-02-04 2009-08-13 Banyan Biomarkers, Inc. Process to diagnose or treat brain injury
AU2010262952B2 (en) 2009-06-19 2016-01-07 Banyan Biomarkers, Inc. Biomarker assay of neurological condition
KR101211280B1 (ko) * 2010-03-26 2012-12-11 가톨릭대학교 산학협력단 신규한 뇌손상 질환 진단용 마커 및 이의 용도
US20130072437A1 (en) 2010-05-28 2013-03-21 Mind-Nrg Sa Neuregulin isoforms,neuregulin polypeptides and uses thereof
WO2012051519A2 (en) 2010-10-14 2012-04-19 The Johns Hopkins University Biomarkers of brain injury
EP3129780A4 (en) 2014-04-07 2017-12-13 Iron Horse Diagnostics Inc. Traumatic brain injury and neurodegenerative biomarkers, methods, and systems
WO2016048488A1 (en) 2014-09-25 2016-03-31 Oxeia Biopharmaceuticals, Inc. Methods of treating traumatic brain injury
CN107864671A (zh) * 2015-05-05 2018-03-30 加利福尼亚大学董事会 星形细胞创伤节和神经创伤生物标志物

Also Published As

Publication number Publication date
US20220299531A1 (en) 2022-09-22
WO2016179426A1 (en) 2016-11-10
US20200278359A1 (en) 2020-09-03
US10557859B2 (en) 2020-02-11
JP6839854B2 (ja) 2021-03-17
US20180364259A1 (en) 2018-12-20
EP3292414A4 (en) 2018-09-26
US12339289B2 (en) 2025-06-24
CN107864671A (zh) 2018-03-30
EP3292414B1 (en) 2021-04-07
US11249094B2 (en) 2022-02-15
JP2018523092A (ja) 2018-08-16
EP3292414A1 (en) 2018-03-14
US20260110699A1 (en) 2026-04-23
ES2873509T3 (es) 2021-11-03

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