IL245177B - A method for improving the sensitivity of detection in the determination of copy number variations - Google Patents
A method for improving the sensitivity of detection in the determination of copy number variationsInfo
- Publication number
- IL245177B IL245177B IL24517716A IL24517716A IL245177B IL 245177 B IL245177 B IL 245177B IL 24517716 A IL24517716 A IL 24517716A IL 24517716 A IL24517716 A IL 24517716A IL 245177 B IL245177 B IL 245177B
- Authority
- IL
- Israel
- Prior art keywords
- sensitivity
- improving
- detection
- copy number
- number variations
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 230000035945 sensitivity Effects 0.000 title 1
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/10—Ploidy or copy number detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Analytical Chemistry (AREA)
- Biomedical Technology (AREA)
- Databases & Information Systems (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Data Mining & Analysis (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- Primary Health Care (AREA)
- Evolutionary Computation (AREA)
- Bioethics (AREA)
- Artificial Intelligence (AREA)
- Software Systems (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361893830P | 2013-10-21 | 2013-10-21 | |
| PCT/US2014/061635 WO2015061359A1 (en) | 2013-10-21 | 2014-10-21 | Method for improving the sensitivity of detection in determining copy number variations |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL245177A0 IL245177A0 (en) | 2016-06-30 |
| IL245177B true IL245177B (en) | 2019-11-28 |
Family
ID=51894216
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL24517716A IL245177B (en) | 2013-10-21 | 2016-04-18 | A method for improving the sensitivity of detection in the determination of copy number variations |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10741269B2 (https=) |
| EP (2) | EP3061021B1 (https=) |
| JP (1) | JP6534191B2 (https=) |
| KR (2) | KR102429186B1 (https=) |
| CN (1) | CN105830077B (https=) |
| AU (2) | AU2014340239B2 (https=) |
| CA (1) | CA2928185C (https=) |
| IL (1) | IL245177B (https=) |
| WO (1) | WO2015061359A1 (https=) |
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| HK1206055A1 (en) | 2012-03-02 | 2015-12-31 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| US9892230B2 (en) | 2012-03-08 | 2018-02-13 | The Chinese University Of Hong Kong | Size-based analysis of fetal or tumor DNA fraction in plasma |
| CN105190656B (zh) | 2013-01-17 | 2018-01-16 | 佩索纳里斯公司 | 用于遗传分析的方法和系统 |
| HK1216655A1 (zh) | 2013-03-13 | 2016-11-25 | Sequenom, Inc. | 用於dna甲基化分析的引物 |
| KR102429186B1 (ko) | 2013-10-21 | 2022-08-03 | 베리나타 헬스, 인코포레이티드 | 사본수 변동을 결정함에 있어서 검출의 감수성을 향상시키기 위한 방법 |
| US11365447B2 (en) | 2014-03-13 | 2022-06-21 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
| CA2950596C (en) * | 2014-05-30 | 2023-10-31 | Verinata Health, Inc. | Detecting fetal sub-chromosomal aneuploidies and copy number variations |
| ES2741400T3 (es) | 2014-07-18 | 2020-02-10 | Univ Hong Kong Chinese | Análisis de patrones de metilación de tejidos en mezcla de ADN |
| US10892035B2 (en) * | 2014-10-10 | 2021-01-12 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
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| WO2016081712A1 (en) * | 2014-11-19 | 2016-05-26 | Bigdatabio, Llc | Systems and methods for genomic manipulations and analysis |
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| US10364467B2 (en) | 2015-01-13 | 2019-07-30 | The Chinese University Of Hong Kong | Using size and number aberrations in plasma DNA for detecting cancer |
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| WO2018099418A1 (en) | 2016-11-30 | 2018-06-07 | The Chinese University Of Hong Kong | Analysis of cell-free dna in urine and other samples |
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| CN108647492B (zh) * | 2018-05-02 | 2019-04-16 | 中国人民解放军军事科学院军事医学研究院 | 一种染色质拓扑相关结构域的表征方法及装置 |
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| KR102215151B1 (ko) | 2018-09-28 | 2021-02-10 | 한양대학교 산학협력단 | 다중 참조 유전체에 기반한 유전체 구조변이 검출 방법 및 구조변이 검출 장치 |
| CN111028888B (zh) * | 2018-10-09 | 2024-07-16 | 北京贝瑞和康生物技术有限公司 | 一种全基因组拷贝数变异的检测方法及其应用 |
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| CN121368638A (zh) * | 2023-06-30 | 2026-01-20 | 因美纳有限公司 | 在测序运行期间修改测序循环或成像以满足定制的覆盖度估计 |
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-
2014
- 2014-10-21 KR KR1020227007542A patent/KR102429186B1/ko active Active
- 2014-10-21 US US15/031,246 patent/US10741269B2/en active Active
- 2014-10-21 EP EP14796611.3A patent/EP3061021B1/en active Active
- 2014-10-21 CA CA2928185A patent/CA2928185C/en active Active
- 2014-10-21 EP EP23168928.2A patent/EP4227947A1/en not_active Withdrawn
- 2014-10-21 KR KR1020167013043A patent/KR102373647B1/ko not_active Expired - Fee Related
- 2014-10-21 AU AU2014340239A patent/AU2014340239B2/en not_active Ceased
- 2014-10-21 CN CN201480070158.4A patent/CN105830077B/zh not_active Expired - Fee Related
- 2014-10-21 JP JP2016525007A patent/JP6534191B2/ja not_active Expired - Fee Related
- 2014-10-21 WO PCT/US2014/061635 patent/WO2015061359A1/en not_active Ceased
-
2016
- 2016-04-18 IL IL24517716A patent/IL245177B/en active IP Right Grant
-
2020
- 2020-01-31 AU AU2020200728A patent/AU2020200728C1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| IL245177A0 (en) | 2016-06-30 |
| US20160239604A1 (en) | 2016-08-18 |
| US10741269B2 (en) | 2020-08-11 |
| EP3061021A1 (en) | 2016-08-31 |
| CA2928185C (en) | 2024-01-30 |
| AU2014340239A1 (en) | 2016-05-12 |
| AU2020200728C1 (en) | 2021-09-09 |
| EP4227947A1 (en) | 2023-08-16 |
| CA2928185A1 (en) | 2015-04-30 |
| JP6534191B2 (ja) | 2019-06-26 |
| AU2020200728A1 (en) | 2020-02-20 |
| WO2015061359A1 (en) | 2015-04-30 |
| AU2014340239B2 (en) | 2019-11-28 |
| KR102429186B1 (ko) | 2022-08-03 |
| CN105830077A (zh) | 2016-08-03 |
| KR102373647B1 (ko) | 2022-03-11 |
| AU2020200728B2 (en) | 2021-05-27 |
| KR20220034929A (ko) | 2022-03-18 |
| CN105830077B (zh) | 2019-07-09 |
| EP3061021B1 (en) | 2023-05-10 |
| BR112016008870A8 (pt) | 2020-03-24 |
| JP2016539630A (ja) | 2016-12-22 |
| KR20160073405A (ko) | 2016-06-24 |
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