SG11201509866TA - Protease-responsive peptide biosensors and methods for analyte detection - Google Patents
Protease-responsive peptide biosensors and methods for analyte detectionInfo
- Publication number
- SG11201509866TA SG11201509866TA SG11201509866TA SG11201509866TA SG11201509866TA SG 11201509866T A SG11201509866T A SG 11201509866TA SG 11201509866T A SG11201509866T A SG 11201509866TA SG 11201509866T A SG11201509866T A SG 11201509866TA SG 11201509866T A SG11201509866T A SG 11201509866TA
- Authority
- SG
- Singapore
- Prior art keywords
- protease
- methods
- analyte detection
- responsive peptide
- peptide biosensors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SG11201509866TA SG11201509866TA (en) | 2013-06-06 | 2014-06-06 | Protease-responsive peptide biosensors and methods for analyte detection |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SG2013043955 | 2013-06-06 | ||
SG11201509866TA SG11201509866TA (en) | 2013-06-06 | 2014-06-06 | Protease-responsive peptide biosensors and methods for analyte detection |
PCT/SG2014/000263 WO2014196932A1 (en) | 2013-06-06 | 2014-06-06 | Protease-responsive peptide biosensors and methods for analyte detection |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201509866TA true SG11201509866TA (en) | 2015-12-30 |
Family
ID=52008440
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201509866TA SG11201509866TA (en) | 2013-06-06 | 2014-06-06 | Protease-responsive peptide biosensors and methods for analyte detection |
Country Status (4)
Country | Link |
---|---|
US (1) | US20160109438A1 (en) |
EP (1) | EP3004375A4 (en) |
SG (1) | SG11201509866TA (en) |
WO (1) | WO2014196932A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY196175A (en) * | 2016-01-11 | 2023-03-20 | Univ Leland Stanford Junior | Chimeric Proteins And Methods Of Regulating Gene Expression |
MY194127A (en) | 2016-01-11 | 2022-11-14 | Univ Leland Stanford Junior | Chimeric proteins and methods of immunotherapy |
US20190360019A1 (en) * | 2016-11-16 | 2019-11-28 | Universal Biosensors Pty Ltd | Cleavage event transduction methods and products |
SG11202000145XA (en) * | 2017-07-12 | 2020-02-27 | Refuge Biotechnologies Inc | Methods and systems for conditionally regulating gene expression |
US20210396762A1 (en) * | 2020-06-19 | 2021-12-23 | Encodia, Inc. | Methods for peptide analysis employing multi-component detection agent and related kits |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6884870B2 (en) * | 1998-03-20 | 2005-04-26 | California Institute Of Technology | Fusion proteins for identifying proteases, protease target sites and regulators of protease activity in living cells |
NO20053354D0 (en) * | 2005-07-11 | 2005-07-11 | Amersham Health As | Optical imaging contrast agent. |
WO2007127538A1 (en) * | 2006-03-16 | 2007-11-08 | Invitrogen Corporation | Methods for assaying protein-protein interaction |
US20100278745A1 (en) * | 2006-12-21 | 2010-11-04 | Norbert Lange | Compounds for fluorescence imaging |
PT2191275E (en) * | 2007-09-04 | 2012-11-16 | Sanofi Sa | Identifying molecules that modulate protein- protein interactions using protease activated reporters |
-
2014
- 2014-06-06 EP EP14808276.1A patent/EP3004375A4/en not_active Withdrawn
- 2014-06-06 SG SG11201509866TA patent/SG11201509866TA/en unknown
- 2014-06-06 WO PCT/SG2014/000263 patent/WO2014196932A1/en active Application Filing
- 2014-06-06 US US14/895,696 patent/US20160109438A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2014196932A1 (en) | 2014-12-11 |
EP3004375A4 (en) | 2017-05-10 |
EP3004375A1 (en) | 2016-04-13 |
US20160109438A1 (en) | 2016-04-21 |
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