IL239178A0 - Peri-carbinols - Google Patents
Peri-carbinolsInfo
- Publication number
- IL239178A0 IL239178A0 IL239178A IL23917815A IL239178A0 IL 239178 A0 IL239178 A0 IL 239178A0 IL 239178 A IL239178 A IL 239178A IL 23917815 A IL23917815 A IL 23917815A IL 239178 A0 IL239178 A0 IL 239178A0
- Authority
- IL
- Israel
- Prior art keywords
- carbinols
- peri
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261740197P | 2012-12-20 | 2012-12-20 | |
| PCT/US2013/076592 WO2014100425A1 (en) | 2012-12-20 | 2013-12-19 | Peri-carbinols |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL239178A0 true IL239178A0 (en) | 2015-07-30 |
Family
ID=50979217
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL239178A IL239178A0 (en) | 2012-12-20 | 2015-06-03 | Peri-carbinols |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9604997B2 (OSRAM) |
| EP (1) | EP2935220A4 (OSRAM) |
| JP (1) | JP2016503797A (OSRAM) |
| KR (1) | KR20150118106A (OSRAM) |
| CN (1) | CN105073714A (OSRAM) |
| AU (1) | AU2013361314A1 (OSRAM) |
| CA (1) | CA2896032A1 (OSRAM) |
| CL (1) | CL2015001754A1 (OSRAM) |
| HK (1) | HK1217325A1 (OSRAM) |
| IL (1) | IL239178A0 (OSRAM) |
| MX (1) | MX2015007916A (OSRAM) |
| RU (1) | RU2015120478A (OSRAM) |
| SG (1) | SG11201504859YA (OSRAM) |
| WO (1) | WO2014100425A1 (OSRAM) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0610308A8 (pt) | 2005-05-26 | 2017-04-25 | Neuron Systems Inc | Composições e métodos para o tratamento de doença retinal |
| US9814701B2 (en) | 2009-12-11 | 2017-11-14 | Aldeyra Therapeutics, Inc. | Compositions and methods for the treatment of macular degeneration |
| JP6284547B2 (ja) | 2012-12-21 | 2018-02-28 | アリオス バイオファーマ インク． | 置換ヌクレオシド、置換ヌクレオチドおよびそれらの類似体 |
| CN105120866B (zh) | 2013-01-23 | 2020-02-14 | 奥尔德拉医疗公司 | 与毒性醛相关的疾病和治疗 |
| JP6266023B2 (ja) | 2013-01-25 | 2018-01-24 | アルデイラ セラピューティクス， インコーポレイテッド | 黄斑変性症の処置における新規トラップ |
| WO2017035077A1 (en) | 2015-08-21 | 2017-03-02 | Aldeyra Therapeutics, Inc. | Deuterated compounds and uses thereof |
| HK1256143A1 (zh) * | 2015-08-21 | 2019-09-13 | Aldeyra Therapeutics, Inc. | 醛結合物和其用途 |
| CN109069530A (zh) | 2016-02-28 | 2018-12-21 | 奥尔德拉医疗公司 | 用环糊精治疗过敏性眼部病状 |
| CA3022665A1 (en) | 2016-05-09 | 2017-11-16 | Aldeyra Therapeutics, Inc. | Combination treatment of ocular inflammatory disorders and diseases |
| CN109640983A (zh) * | 2016-08-22 | 2019-04-16 | 奥尔德拉医疗公司 | 醛捕获化合物和其用途 |
| CN110431130A (zh) | 2017-03-16 | 2019-11-08 | 奥尔德拉医疗公司 | 多晶型化合物和其用途 |
| CN111356451A (zh) | 2017-10-10 | 2020-06-30 | 奥尔德拉医疗公司 | 炎性病症的治疗 |
| US12006298B2 (en) | 2018-08-06 | 2024-06-11 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| US11197821B2 (en) | 2018-09-25 | 2021-12-14 | Aldeyra Therapeutics, Inc. | Formulations for treatment of dry eye disease |
| JP7706758B2 (ja) | 2019-03-26 | 2025-07-14 | アルデイラ セラピューティクス， インコーポレイテッド | 眼科用製剤およびその使用 |
| CA3137301A1 (en) | 2019-05-02 | 2020-11-05 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| US12098132B2 (en) | 2019-05-02 | 2024-09-24 | Aldeyra Therapeutics, Inc. | Process for preparation of aldehyde scavenger and intermediates |
| EP4149470A4 (en) | 2020-05-13 | 2024-04-24 | Aldeyra Therapeutics, Inc. | Pharmaceutical formulations and uses thereof |
| MX2023000263A (es) | 2020-07-16 | 2023-03-29 | Dermavant Sciences GmbH | Compuestos isoquinolina y su uso en el tratamiento del desequilibrio de ahr. |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2086186A (en) | 1933-10-10 | 1937-07-06 | Us Rubber Co | Treatment of rubber |
| SU509046A1 (ru) | 1975-02-21 | 1984-06-23 | Всесоюзный научно-исследовательский химико-фармацевтический институт им.Серго Орджоникидзе | Производные 2-карбэтокси-3-аминоиндола,про вл ющие противовоспалительную активность, и способ их получени |
| US4675332A (en) | 1984-12-10 | 1987-06-23 | Warner-Lambert Company | Acidic tetrazolyl substituted indole compounds and their use as antiallergy agents |
| GB8610981D0 (en) | 1986-05-06 | 1986-06-11 | Ici America Inc | Quinoline amides |
| CA2054339C (en) | 1990-11-02 | 2002-12-24 | Francesco G. Salituro | 3-amidoindolyl derivatives |
| US5668117A (en) | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
| US6444221B1 (en) | 1992-06-30 | 2002-09-03 | Howard K. Shapiro | Methods of treating chronic inflammatory diseases using carbonyl trapping agents |
| US20050090553A1 (en) | 1992-06-30 | 2005-04-28 | Shapiro Howard K. | Compositions and method for treatment of chronic inflammatory diseases |
| US5472954A (en) | 1992-07-14 | 1995-12-05 | Cyclops H.F. | Cyclodextrin complexation |
| US5493027A (en) | 1993-01-22 | 1996-02-20 | Board Of Regents, The University Of Texas System | Anticonvulsive agents and uses thereof |
| US5597823A (en) | 1995-01-27 | 1997-01-28 | Abbott Laboratories | Tricyclic substituted hexahydrobenz [e]isoindole alpha-1 adrenergic antagonists |
| AU723758B2 (en) | 1996-08-01 | 2000-09-07 | Dow Agrosciences Llc | 4-substituted quinoline derivatives having fungicidal activity |
| EP0980362B1 (de) | 1997-05-02 | 2006-08-16 | Schering Aktiengesellschaft | Substituierte heterocyclen und deren verwendung in arzneimitteln |
| JP2004500308A (ja) | 1998-03-12 | 2004-01-08 | ノボ ノルディスク アクティーゼルスカブ | プロテインチロシンホスアターゼのモジュレーター |
| US6498154B1 (en) | 1999-05-04 | 2002-12-24 | Wyeth | Cyclic regimens using quinazolinone and benzoxazine derivatives |
| AU1735001A (en) | 1999-12-10 | 2001-06-18 | Senju Pharmaceutical Co., Ltd. | Cyclodextrin-containing pharmaceutical composition |
| FR2827599A1 (fr) | 2001-07-20 | 2003-01-24 | Neuro3D | Composes derives de quinoleine et quinoxaline,preparation et utilisations |
| US20060014786A1 (en) | 2002-05-17 | 2006-01-19 | Rajeev Raut | Opthalmic pharmaceutical compositions and methods for treating ocular inflammation |
| CA2451267A1 (en) | 2002-12-13 | 2004-06-13 | Warner-Lambert Company Llc | Pharmaceutical uses for alpha2delta ligands |
| EP2327401A3 (en) | 2003-03-14 | 2011-10-19 | University of Washington | Retinoid Replacements and Opsin Agonists and Methods for the Use Thereof |
| US20060111318A1 (en) | 2003-04-18 | 2006-05-25 | Advanced Medicine Research Institute | Agent for treating eye diseases |
| JP4564920B2 (ja) | 2003-04-18 | 2010-10-20 | 株式会社最先端医学研究所 | 眼に適用する疾患治療剤 |
| US7297709B2 (en) | 2003-05-22 | 2007-11-20 | Abbott Laboratories | Indazole, benzisoxazole, and benzisothiazole kinase inhibitors |
| WO2005035506A1 (ja) | 2003-10-15 | 2005-04-21 | Ube Industries, Ltd. | 新規インダゾール誘導体 |
| ZA200604403B (en) | 2003-11-20 | 2007-09-26 | Othera Pharmaceuticals Inc | Amelioration of macular degeneration and other ophthalmic diseases |
| US20050197292A1 (en) | 2004-01-30 | 2005-09-08 | Glennda Smithson | Compositions and methods for treating T-cell mediated pathological conditions |
| AU2005215778B2 (en) | 2004-02-17 | 2009-03-12 | President And Fellows Of Harvard College | Management of ophthalmologic disorders, including macular degeneration |
| US20050234018A1 (en) | 2004-04-15 | 2005-10-20 | Allergan, Inc. | Drug delivery to the back of the eye |
| WO2006002473A1 (en) | 2004-07-02 | 2006-01-12 | Adelaide Research & Innovation Pty Ltd | Method of controlling damage mediated by alpha, beta-unsaturated aldehydes |
| US20070287716A1 (en) * | 2004-10-28 | 2007-12-13 | Hu Essa H | Pyrimidine and Quinoline Potentiators of Metabotropic Glutamate Receptors |
| TW200640443A (en) | 2005-02-23 | 2006-12-01 | Alcon Inc | Methods for treating ocular angiogenesis, retinal edema, retinal ischemia, and diabetic retinopathy using selective RTK inhibitors |
| BRPI0610308A8 (pt) | 2005-05-26 | 2017-04-25 | Neuron Systems Inc | Composições e métodos para o tratamento de doença retinal |
| BRPI0710737A2 (pt) * | 2006-04-14 | 2011-05-10 | Prana Biotechnology Ltd | uso de compostos pb-10 33 éteis para o tratamento de degeneraÇço macular relacionada À idade (amd), assim como referidos compostos |
| AU2007280984A1 (en) * | 2006-07-25 | 2008-02-07 | Envivo Pharmaceutical Inc. | Quinoline derivatives |
| WO2009045479A1 (en) | 2007-10-05 | 2009-04-09 | Acucela Inc. | Alkoxy compounds for disease treatment |
| BRPI0917634A2 (pt) | 2008-08-12 | 2015-11-17 | Sirtris Pharmaceuticals Inc | benzoxazolas, benztiazolas e análogos relacionados como moduladores de sirtuína |
| WO2010133672A1 (en) * | 2009-05-20 | 2010-11-25 | Clanotech Ab | Derivatives of quinoline-3-carboxylic acid and their medical use |
| EP2477594A4 (en) | 2009-07-15 | 2013-03-13 | Univ Vanderbilt | ISOKETAL CATCHER AND TREATMENT OF DISEASES WITH OXIDATIVE INJURY |
| CA2783699C (en) | 2009-12-08 | 2019-01-15 | Case Western Reserve University | Primary amine compounds for treating ocular disorders |
| US9814701B2 (en) | 2009-12-11 | 2017-11-14 | Aldeyra Therapeutics, Inc. | Compositions and methods for the treatment of macular degeneration |
| CN103562186B (zh) | 2011-01-12 | 2017-02-15 | 帆德制药股份有限公司 | 作为toll样受体调节剂的取代的苯并氮杂卓 |
| CN103442735B (zh) | 2011-01-31 | 2016-11-09 | 特米拉公司 | 用于减轻技术领域中所不希望的医学状况的有效要素 |
| CN105120866B (zh) | 2013-01-23 | 2020-02-14 | 奥尔德拉医疗公司 | 与毒性醛相关的疾病和治疗 |
| JP6266023B2 (ja) | 2013-01-25 | 2018-01-24 | アルデイラ セラピューティクス， インコーポレイテッド | 黄斑変性症の処置における新規トラップ |
| EP3151818A4 (en) | 2014-06-04 | 2018-05-30 | Case Western Reserve University | Compositions and methods of treating diabetic retinopathy |
| US10363231B2 (en) | 2014-11-24 | 2019-07-30 | Case Western Reserve University | Compounds and methods of treating ocular disorders |
-
2013
- 2013-12-19 CA CA2896032A patent/CA2896032A1/en not_active Abandoned
- 2013-12-19 US US14/653,771 patent/US9604997B2/en active Active
- 2013-12-19 AU AU2013361314A patent/AU2013361314A1/en not_active Abandoned
- 2013-12-19 HK HK16105238.3A patent/HK1217325A1/zh unknown
- 2013-12-19 WO PCT/US2013/076592 patent/WO2014100425A1/en not_active Ceased
- 2013-12-19 JP JP2015549717A patent/JP2016503797A/ja not_active Withdrawn
- 2013-12-19 RU RU2015120478A patent/RU2015120478A/ru unknown
- 2013-12-19 MX MX2015007916A patent/MX2015007916A/es unknown
- 2013-12-19 KR KR1020157019397A patent/KR20150118106A/ko not_active Withdrawn
- 2013-12-19 SG SG11201504859YA patent/SG11201504859YA/en unknown
- 2013-12-19 CN CN201380067618.3A patent/CN105073714A/zh active Pending
- 2013-12-19 EP EP13865015.5A patent/EP2935220A4/en not_active Withdrawn
-
2015
- 2015-06-03 IL IL239178A patent/IL239178A0/en unknown
- 2015-06-18 CL CL2015001754A patent/CL2015001754A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20150118106A (ko) | 2015-10-21 |
| CL2015001754A1 (es) | 2015-11-06 |
| SG11201504859YA (en) | 2015-07-30 |
| MX2015007916A (es) | 2016-04-07 |
| EP2935220A4 (en) | 2016-04-27 |
| US9604997B2 (en) | 2017-03-28 |
| CN105073714A (zh) | 2015-11-18 |
| HK1217325A1 (zh) | 2017-01-06 |
| RU2015120478A (ru) | 2017-01-25 |
| AU2013361314A1 (en) | 2015-07-02 |
| US20150344432A1 (en) | 2015-12-03 |
| EP2935220A1 (en) | 2015-10-28 |
| JP2016503797A (ja) | 2016-02-08 |
| WO2014100425A1 (en) | 2014-06-26 |
| CA2896032A1 (en) | 2014-06-26 |
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