IL231714B - Sialic acid analogs - Google Patents
Sialic acid analogsInfo
- Publication number
- IL231714B IL231714B IL231714A IL23171414A IL231714B IL 231714 B IL231714 B IL 231714B IL 231714 A IL231714 A IL 231714A IL 23171414 A IL23171414 A IL 23171414A IL 231714 B IL231714 B IL 231714B
- Authority
- IL
- Israel
- Prior art keywords
- sialic acid
- acid analogs
- analogs
- sialic
- acid
- Prior art date
Links
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical class CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/02—Acyclic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/10—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to heterocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
- C07H7/02—Acyclic radicals
- C07H7/027—Keto-aldonic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161550610P | 2011-10-24 | 2011-10-24 | |
| PCT/US2012/061737 WO2013063149A1 (en) | 2011-10-24 | 2012-10-24 | Sialic acid analogs |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL231714A0 IL231714A0 (en) | 2014-05-28 |
| IL231714B true IL231714B (en) | 2018-10-31 |
Family
ID=48168447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL231714A IL231714B (en) | 2011-10-24 | 2014-03-26 | Sialic acid analogs |
Country Status (13)
| Country | Link |
|---|---|
| US (5) | US8840926B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2771348B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6196224B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR102049214B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN103974965B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2012328874B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112014009760B1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2849114C (cg-RX-API-DMAC7.html) |
| ES (1) | ES2807890T3 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1201067A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL231714B (cg-RX-API-DMAC7.html) |
| MX (1) | MX347541B (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013063149A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9241896B2 (en) | 2008-12-19 | 2016-01-26 | Ultragenyx Pharmaceutical Inc. | Methods and formulations for treating sialic acid deficiencies |
| KR20140003380A (ko) | 2010-07-13 | 2014-01-09 | 울트라제닉스 파마수티컬 인코포레이티드 | 시알산 결함 치료용 방법들 및 제형들 |
| HK1201067A1 (en) | 2011-10-24 | 2015-08-21 | 罕见病药物研发公司 | Sialic acid analogs |
| JP2015504094A (ja) * | 2012-01-18 | 2015-02-05 | ウルトラジェニックス ファーマシューティカル インコーポレイテッド | シアル酸欠乏を処置するための方法および製剤 |
| AR106025A1 (es) | 2015-09-14 | 2017-12-06 | Ultragenyx Pharmaceutical Inc | Formas cristalinas de ácido siálico o una sal o solvato de este |
| EP4665860A1 (en) * | 2023-02-17 | 2025-12-24 | Ultragenyx Pharmaceutical Inc. | Crystalline forms of sialic acid derivatives and methods for their use |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6168418A (ja) | 1984-09-11 | 1986-04-08 | Kanto Ishi Pharma Co Ltd | 去痰薬 |
| JPS63139193A (ja) * | 1986-11-28 | 1988-06-10 | Mect Corp | シアル酸誘導体１，７−ラクトン |
| US6156544A (en) | 1993-06-09 | 2000-12-05 | Glaxo Group Limited | Process for the preparation of N-acetylneuraminic acid |
| EP0820305A2 (en) | 1995-04-04 | 1998-01-28 | Wound Healing of Oklahoma | Cancer treatment by photodynamic therapy, in combination with an immunoadjuvant |
| US5624677A (en) | 1995-06-13 | 1997-04-29 | Pentech Pharmaceuticals, Inc. | Controlled release of drugs delivered by sublingual or buccal administration |
| CN1183154C (zh) | 1998-04-10 | 2005-01-05 | 三菱化学株式会社 | 含有唾液酸衍生物的固体分散体 |
| KR20030006721A (ko) | 2001-07-14 | 2003-01-23 | 삼성전자 주식회사 | 리소그라피 시스템 및 이를 이용한 레티클 표면의 파티클제거방법 |
| ATE503498T1 (de) | 2002-06-21 | 2011-04-15 | Novo Nordisk Healthcare Ag | Pegylierte glykoformen von faktor vii |
| US7238677B2 (en) | 2003-03-28 | 2007-07-03 | Kimberly-Clark Worldwide, Inc. | Prevention of urogenital infections |
| US20050201974A1 (en) * | 2003-12-09 | 2005-09-15 | Spherics, Inc. | Bioadhesive polymers with catechol functionality |
| AU2005328670B2 (en) | 2005-03-03 | 2011-08-11 | Mannatech, Inc. | Methods and compositions for modified release of nutritional supplements |
| US20100226855A1 (en) * | 2006-03-02 | 2010-09-09 | Spherics, Inc. | Rate-Controlled Oral Dosage Formulations |
| WO2008027557A2 (en) * | 2006-08-31 | 2008-03-06 | Spherics, Inc. | Topiramate compositions and methods of enhancing its bioavailability |
| CA2680842C (en) | 2007-05-31 | 2015-11-24 | Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services National Institutes Of Health | N-acetyl mannosamine or derivatives thereof for use in treating a kidney disorder in a mammal |
| EP2192923A2 (en) | 2007-08-27 | 2010-06-09 | Massachusetts Institute of Technology | Bi-functional polymer-attached inhibitors of influenza virus |
| CN102316730A (zh) | 2008-05-09 | 2012-01-11 | 天雅瑞药业有限公司 | 用于减轻全身性炎症和/或血管炎症的n-乙酰半胱氨酸(nac)的控释 |
| KR101116864B1 (ko) | 2008-08-01 | 2012-02-29 | 주식회사 베네비오 | 고지혈증, 지방간 또는 비만의 예방 또는 치료용 조성물 |
| US20100159001A1 (en) | 2008-12-19 | 2010-06-24 | Cardinal John R | Extended-Release Pharmaceutical Formulations |
| US20100160363A1 (en) | 2008-12-19 | 2010-06-24 | Aaipharma Services Corp. | Extended-release pharmaceutical formulations |
| US9241896B2 (en) | 2008-12-19 | 2016-01-26 | Ultragenyx Pharmaceutical Inc. | Methods and formulations for treating sialic acid deficiencies |
| JP5626734B2 (ja) * | 2009-05-15 | 2014-11-19 | 公益財団法人ヒューマンサイエンス振興財団 | Ｇｎｅタンパク質の機能低下に起因する疾患の治療用医薬剤、食品組成物 |
| KR20140003380A (ko) | 2010-07-13 | 2014-01-09 | 울트라제닉스 파마수티컬 인코포레이티드 | 시알산 결함 치료용 방법들 및 제형들 |
| HK1201067A1 (en) | 2011-10-24 | 2015-08-21 | 罕见病药物研发公司 | Sialic acid analogs |
| JP2015504094A (ja) | 2012-01-18 | 2015-02-05 | ウルトラジェニックス ファーマシューティカル インコーポレイテッド | シアル酸欠乏を処置するための方法および製剤 |
| KR102646509B1 (ko) | 2015-01-28 | 2024-03-11 | 교와 핫꼬 바이오 가부시키가이샤 | N-아세틸노이라민산암모늄염·무수화물의 결정 및 그 제조 방법 |
| AR106025A1 (es) | 2015-09-14 | 2017-12-06 | Ultragenyx Pharmaceutical Inc | Formas cristalinas de ácido siálico o una sal o solvato de este |
-
2012
- 2012-10-24 HK HK15101526.4A patent/HK1201067A1/xx unknown
- 2012-10-24 EP EP12843460.2A patent/EP2771348B1/en active Active
- 2012-10-24 US US13/659,550 patent/US8840926B2/en active Active
- 2012-10-24 CA CA2849114A patent/CA2849114C/en active Active
- 2012-10-24 CN CN201280052218.0A patent/CN103974965B/zh active Active
- 2012-10-24 AU AU2012328874A patent/AU2012328874B2/en active Active
- 2012-10-24 KR KR1020147013997A patent/KR102049214B1/ko active Active
- 2012-10-24 WO PCT/US2012/061737 patent/WO2013063149A1/en not_active Ceased
- 2012-10-24 JP JP2014537380A patent/JP6196224B2/ja active Active
- 2012-10-24 ES ES12843460T patent/ES2807890T3/es active Active
- 2012-10-24 BR BR112014009760-7A patent/BR112014009760B1/pt active IP Right Grant
- 2012-10-24 MX MX2014004928A patent/MX347541B/es active IP Right Grant
-
2014
- 2014-03-26 IL IL231714A patent/IL231714B/en active IP Right Grant
- 2014-08-15 US US14/461,295 patent/US9221858B2/en active Active
-
2015
- 2015-11-18 US US14/944,779 patent/US10065981B2/en active Active
-
2018
- 2018-07-31 US US16/050,343 patent/US10457701B2/en active Active
-
2019
- 2019-09-16 US US16/571,589 patent/US10889607B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2771348A4 (en) | 2015-09-09 |
| AU2012328874A1 (en) | 2014-04-10 |
| BR112014009760A8 (pt) | 2018-01-16 |
| CN103974965A (zh) | 2014-08-06 |
| US9221858B2 (en) | 2015-12-29 |
| BR112014009760A2 (pt) | 2017-04-18 |
| CN103974965B (zh) | 2019-09-24 |
| CA2849114A1 (en) | 2013-05-02 |
| BR112014009760B1 (pt) | 2022-11-29 |
| MX347541B (es) | 2017-04-28 |
| US20200131215A1 (en) | 2020-04-30 |
| ES2807890T3 (es) | 2021-02-24 |
| KR102049214B1 (ko) | 2019-11-28 |
| US20160297846A1 (en) | 2016-10-13 |
| JP6196224B2 (ja) | 2017-09-13 |
| US10065981B2 (en) | 2018-09-04 |
| KR20140084277A (ko) | 2014-07-04 |
| US10457701B2 (en) | 2019-10-29 |
| EP2771348B1 (en) | 2020-05-20 |
| EP2771348A1 (en) | 2014-09-03 |
| CA2849114C (en) | 2020-12-15 |
| WO2013063149A1 (en) | 2013-05-02 |
| US8840926B2 (en) | 2014-09-23 |
| MX2014004928A (es) | 2014-11-10 |
| HK1201067A1 (en) | 2015-08-21 |
| US20190127409A1 (en) | 2019-05-02 |
| US10889607B2 (en) | 2021-01-12 |
| US20130122094A1 (en) | 2013-05-16 |
| JP2014530882A (ja) | 2014-11-20 |
| US20150038693A1 (en) | 2015-02-05 |
| IL231714A0 (en) | 2014-05-28 |
| AU2012328874B2 (en) | 2017-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed |