IL231637A0 - Recombinant f rsv nano-particle vaccine for respiratory syncytial virus - Google Patents
Recombinant f rsv nano-particle vaccine for respiratory syncytial virusInfo
- Publication number
- IL231637A0 IL231637A0 IL231637A IL23163714A IL231637A0 IL 231637 A0 IL231637 A0 IL 231637A0 IL 231637 A IL231637 A IL 231637A IL 23163714 A IL23163714 A IL 23163714A IL 231637 A0 IL231637 A0 IL 231637A0
- Authority
- IL
- Israel
- Prior art keywords
- rsv
- vaccine
- respiratory syncytial
- syncytial virus
- nanoparticle
- Prior art date
Links
- 241000725643 Respiratory syncytial virus Species 0.000 title 1
- 239000002105 nanoparticle Substances 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/115—Paramyxoviridae, e.g. parainfluenza virus
- C07K14/135—Respiratory syncytial virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161542040P | 2011-09-30 | 2011-09-30 | |
| US201161542721P | 2011-10-03 | 2011-10-03 | |
| US201261611834P | 2012-03-16 | 2012-03-16 | |
| US201261614286P | 2012-03-22 | 2012-03-22 | |
| PCT/US2012/057546 WO2013049342A1 (en) | 2011-09-30 | 2012-09-27 | Recombinant nanoparticle rsv f vaccine for respiratory syncytial virus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL231637A0 true IL231637A0 (en) | 2014-05-28 |
Family
ID=47996397
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL231637A IL231637A0 (en) | 2011-09-30 | 2014-03-20 | Recombinant f rsv nano-particle vaccine for respiratory syncytial virus |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20130122032A1 (enExample) |
| EP (1) | EP2760469A4 (enExample) |
| JP (1) | JP2014530010A (enExample) |
| KR (1) | KR20140077169A (enExample) |
| CN (2) | CN105381457A (enExample) |
| AU (1) | AU2013201495B2 (enExample) |
| BR (1) | BR112014007616A2 (enExample) |
| CA (1) | CA2849471A1 (enExample) |
| HK (1) | HK1222125A1 (enExample) |
| IL (1) | IL231637A0 (enExample) |
| MX (1) | MX2014003777A (enExample) |
| RU (1) | RU2014117068A (enExample) |
| SG (2) | SG10201602434UA (enExample) |
| WO (1) | WO2013049342A1 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11446374B2 (en) | 2008-12-09 | 2022-09-20 | Novavax, Inc. | Modified RSV F proteins and methods of their use |
| KR101691574B1 (ko) | 2008-12-09 | 2017-01-02 | 노바백스, 인코포레이티드 | 변형 ｒｓｖ ｆ 단백질 및 이들의 사용 방법 |
| HK1221641A1 (zh) * | 2013-04-08 | 2017-06-09 | Medimmune, Llc | 疫苗组合物及使用方法 |
| CA2925201A1 (en) * | 2013-09-24 | 2015-04-02 | Massachusetts Institute Of Technology | Self-assembled nanoparticle vaccines |
| CN105087643A (zh) * | 2014-04-16 | 2015-11-25 | 中国科学院上海巴斯德研究所 | 重组表达人呼吸道合胞病毒f1蛋白胞外区的方法及表达系统 |
| WO2015195961A1 (en) * | 2014-06-18 | 2015-12-23 | Georgia State University And Research Foundation, Inc. | Recombinant rsv reporter virus |
| US9630994B2 (en) | 2014-11-03 | 2017-04-25 | University Of Washington | Polypeptides for use in self-assembling protein nanostructures |
| CN108348593B (zh) * | 2015-08-31 | 2022-08-16 | 泰克诺瓦克斯股份有限公司 | 基于人呼吸道合胞病毒(hrsv)病毒样颗粒(vlps)的疫苗 |
| CA2997181A1 (en) * | 2015-09-02 | 2017-03-09 | Janssen Vaccines & Prevention B.V. | Stabilized viral class i fusion proteins |
| IL257800B2 (en) | 2015-09-03 | 2023-11-01 | Novavax Inc | Immune compositions with improved stability and immunogenicity |
| CN106547635B (zh) | 2015-09-18 | 2020-10-09 | 阿里巴巴集团控股有限公司 | 一种作业的操作重试方法和装置 |
| PE20240817A1 (es) | 2015-12-23 | 2024-04-18 | Pfizer | Mutantes de proteina f de rsv |
| PT3439672T (pt) * | 2016-04-05 | 2021-02-24 | Janssen Vaccines & Prevention Bv | Proteína f do rsv pré-fusão solúvel e estabilizada para uso na profilaxia de infeção por rsv |
| CN106124767A (zh) * | 2016-05-12 | 2016-11-16 | 广州瑞辉生物科技股份有限公司 | 呼吸道合胞病毒IgA抗体检测试纸条及其检测方法 |
| CN110352072A (zh) * | 2016-10-03 | 2019-10-18 | 马萨诸塞大学 | 用于免疫免疫前受试者以抵抗呼吸道合胞病毒(rsv)的方法 |
| SG11201908376UA (en) * | 2017-03-15 | 2019-10-30 | Novavax Inc | Methods and compositions for inducing immune responses against clostridium difficile |
| SG11201908999QA (en) | 2017-04-04 | 2019-10-30 | Univ Washington | Self-assembling protein nanostructures displaying paramyxovirus and/or pneumovirus f proteins and their use |
| CN107050446B (zh) * | 2017-04-19 | 2020-08-11 | 武汉博沃生物科技有限公司 | 经修饰的季节流感-rsv联合疫苗及其制备方法 |
| US12083228B2 (en) | 2017-07-24 | 2024-09-10 | Novavax, Inc. | Methods and compositions for treating respiratory disease |
| WO2019063844A1 (en) * | 2017-09-29 | 2019-04-04 | Universiteit Antwerpen | VACCINATION AGAINST SYNCYTIAL RESPIRATORY VIRUS |
| CA3095216A1 (en) | 2018-02-28 | 2019-09-06 | University Of Washington | Self-asssembling nanostructure vaccines |
| AU2019238171B2 (en) | 2018-03-19 | 2026-01-08 | Novavax, Inc. | Multivalent influenza nanoparticle vaccines |
| CA3115979A1 (en) * | 2018-10-12 | 2020-04-16 | Sk Bioscience Co., Ltd. | Recombinant rsv live vaccine strain and production method therefor |
| US12370252B2 (en) | 2018-10-29 | 2025-07-29 | Emory University | RSV virus-like particles and methods of use thereof |
| KR102725189B1 (ko) * | 2018-11-01 | 2024-10-31 | 에스케이바이오사이언스(주) | 재조합 호흡기 세포융합 바이러스 f 단백질 및 이를 포함하는 백신 조성물 |
| AU2020227545B2 (en) * | 2019-02-28 | 2023-10-19 | Km Biologics Co., Ltd. | RSV F/G chimeric vaccine |
| CN110229219B (zh) * | 2019-06-21 | 2021-03-30 | 中国科学院武汉病毒研究所 | 一种新型的呼吸道合胞病毒疫苗抗原的制备方法及其用途 |
| KR20220141302A (ko) * | 2020-01-27 | 2022-10-19 | 노바백스, 인코포레이티드 | 코로나 바이러스 백신 제제 |
| US10953089B1 (en) | 2020-01-27 | 2021-03-23 | Novavax, Inc. | Coronavirus vaccine formulations |
| MX2022012361A (es) * | 2020-04-02 | 2022-10-21 | Janssen Vaccines & Prevention Bv | Composiciones de vacuna estabilizadas. |
| KR102721070B1 (ko) * | 2020-11-27 | 2024-10-24 | 한국과학기술연구원 | Rsvf를 발현하는 엑소좀 및 이의 용도 |
| CN113855796B (zh) * | 2021-07-30 | 2024-01-26 | 河北医科大学 | 卡介苗作为呼吸道合胞病毒灭活疫苗佐剂的应用 |
| CN118434756A (zh) * | 2021-11-19 | 2024-08-02 | 达冕生物有限公司 | 核糖核酸呼吸道合胞病毒（rsv）疫苗的组合物和方法 |
| KR102785012B1 (ko) | 2021-12-14 | 2025-03-20 | 경희대학교 산학협력단 | Rsv 항원 단백질을 포함하는 바이러스 유사입자 및 이를 이용한 백신 |
| TW202417469A (zh) * | 2022-09-01 | 2024-05-01 | 美商諾瓦瓦克斯股份有限公司 | 純化供用於疫苗組成物之具有疏水性膜結構域的病毒蛋白的下游程序 |
| CN117986382B (zh) * | 2022-11-04 | 2025-04-01 | 北京康乐卫士生物技术股份有限公司 | 针对rsv的重组亚单位疫苗及其应用 |
| WO2024260446A1 (zh) * | 2023-06-21 | 2024-12-26 | 深圳深信生物科技有限公司 | 呼吸道合胞病毒(rsv)疫苗 |
| WO2024259624A1 (en) * | 2023-06-21 | 2024-12-26 | Shenzhen Genius Biotech Service Co. Ltd | A modified rsv f protein, a nanoparticle, a composition and a vaccine against respiratory syncytial virus infection |
| WO2025026448A1 (zh) * | 2023-08-03 | 2025-02-06 | 广州穗和生物技术有限公司 | 修饰的呼吸道合胞病毒f蛋白及其用途 |
| WO2025051250A1 (zh) * | 2023-09-07 | 2025-03-13 | 北京科兴中维生物技术有限公司 | 呼吸道合胞病毒f蛋白及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006524511A (ja) * | 2003-04-25 | 2006-11-02 | メッドイミューン バクシーンズ，インコーポレイティド | メタニューモウイルス由来の異種抗原を含む組換えパラインフルエンザウイルス発現系およびワクチン |
| CA2684578A1 (en) * | 2007-03-21 | 2008-09-25 | Id Biomedical Corporation Of Quebec | Chimeric antigens |
| JP2010533737A (ja) * | 2007-07-19 | 2010-10-28 | ノババックス，インコーポレイテッド | キメラ水痘帯状疱疹ウイルス−ウイルス様粒子 |
| KR101617895B1 (ko) * | 2007-12-24 | 2016-05-03 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 재조합 ｒｓｖ 항원 |
| WO2009108689A1 (en) * | 2008-02-25 | 2009-09-03 | Novavax, Inc. | Sugar glassified virus like particles (vlps) |
| KR101027159B1 (ko) * | 2008-07-28 | 2011-04-05 | 뮤추얼아이피서비스(주) | 타겟 영상 검출 장치 및 그 방법 |
| KR101691574B1 (ko) * | 2008-12-09 | 2017-01-02 | 노바백스, 인코포레이티드 | 변형 ｒｓｖ ｆ 단백질 및 이들의 사용 방법 |
| WO2010077712A1 (en) * | 2008-12-09 | 2010-07-08 | Novavax, Inc. | Bovine respiratory syncytial virus virus-like particle (vlps) |
-
2012
- 2012-09-27 SG SG10201602434UA patent/SG10201602434UA/en unknown
- 2012-09-27 SG SG11201400999VA patent/SG11201400999VA/en unknown
- 2012-09-27 EP EP12835033.7A patent/EP2760469A4/en not_active Withdrawn
- 2012-09-27 CN CN201510769961.3A patent/CN105381457A/zh active Pending
- 2012-09-27 CA CA2849471A patent/CA2849471A1/en not_active Abandoned
- 2012-09-27 US US13/629,107 patent/US20130122032A1/en not_active Abandoned
- 2012-09-27 KR KR1020147009538A patent/KR20140077169A/ko not_active Withdrawn
- 2012-09-27 BR BR112014007616A patent/BR112014007616A2/pt active Search and Examination
- 2012-09-27 CN CN201280059282.1A patent/CN104080476A/zh active Pending
- 2012-09-27 WO PCT/US2012/057546 patent/WO2013049342A1/en not_active Ceased
- 2012-09-27 JP JP2014533316A patent/JP2014530010A/ja active Pending
- 2012-09-27 RU RU2014117068/10A patent/RU2014117068A/ru not_active Application Discontinuation
- 2012-09-27 MX MX2014003777A patent/MX2014003777A/es unknown
- 2012-09-27 AU AU2013201495A patent/AU2013201495B2/en not_active Ceased
-
2014
- 2014-03-20 IL IL231637A patent/IL231637A0/en unknown
-
2015
- 2015-02-27 US US14/634,171 patent/US20150306207A1/en not_active Abandoned
- 2015-02-27 US US14/634,162 patent/US20150335730A1/en not_active Abandoned
-
2016
- 2016-08-31 HK HK16110329.3A patent/HK1222125A1/zh unknown
-
2017
- 2017-02-15 US US15/433,759 patent/US20170319682A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| MX2014003777A (es) | 2015-05-15 |
| SG10201602434UA (en) | 2016-05-30 |
| SG11201400999VA (en) | 2014-07-30 |
| US20130122032A1 (en) | 2013-05-16 |
| US20170319682A1 (en) | 2017-11-09 |
| US20150335730A1 (en) | 2015-11-26 |
| AU2013201495B2 (en) | 2015-12-03 |
| US20150306207A1 (en) | 2015-10-29 |
| KR20140077169A (ko) | 2014-06-23 |
| AU2013201495A1 (en) | 2013-04-18 |
| WO2013049342A1 (en) | 2013-04-04 |
| CN105381457A (zh) | 2016-03-09 |
| HK1222125A1 (zh) | 2017-06-23 |
| RU2014117068A (ru) | 2015-11-10 |
| CA2849471A1 (en) | 2013-04-04 |
| EP2760469A1 (en) | 2014-08-06 |
| EP2760469A4 (en) | 2015-03-18 |
| JP2014530010A (ja) | 2014-11-17 |
| CN104080476A (zh) | 2014-10-01 |
| BR112014007616A2 (pt) | 2017-04-04 |
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