IL227490A0 - quinazolinone inhibitors of dynein - Google Patents

quinazolinone inhibitors of dynein

Info

Publication number
IL227490A0
IL227490A0 IL227490A IL22749013A IL227490A0 IL 227490 A0 IL227490 A0 IL 227490A0 IL 227490 A IL227490 A IL 227490A IL 22749013 A IL22749013 A IL 22749013A IL 227490 A0 IL227490 A0 IL 227490A0
Authority
IL
Israel
Prior art keywords
dynein
quinazolinone
inhibitors
quinazolinone inhibitors
Prior art date
Application number
IL227490A
Other languages
English (en)
Hebrew (he)
Original Assignee
Univ Leland Stanford Junior
James K Chen
Tarun M Kapoor
Ari J Firestone
Joshua S Weinger
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leland Stanford Junior, James K Chen, Tarun M Kapoor, Ari J Firestone, Joshua S Weinger filed Critical Univ Leland Stanford Junior
Publication of IL227490A0 publication Critical patent/IL227490A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL227490A 2011-01-20 2013-07-15 quinazolinone inhibitors of dynein IL227490A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161434545P 2011-01-20 2011-01-20
PCT/US2012/021639 WO2012099916A1 (en) 2011-01-20 2012-01-18 Quinazolinone inhibitors of dynein

Publications (1)

Publication Number Publication Date
IL227490A0 true IL227490A0 (en) 2013-09-30

Family

ID=45774309

Family Applications (1)

Application Number Title Priority Date Filing Date
IL227490A IL227490A0 (en) 2011-01-20 2013-07-15 quinazolinone inhibitors of dynein

Country Status (7)

Country Link
US (1) US9145376B2 (enExample)
EP (1) EP2665712A1 (enExample)
JP (1) JP2014506565A (enExample)
AU (1) AU2012207393A1 (enExample)
CA (1) CA2824925A1 (enExample)
IL (1) IL227490A0 (enExample)
WO (1) WO2012099916A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102015221969A1 (de) * 2015-11-09 2017-05-11 Technische Universität Dresden Verfahren zur automatisierten Detektion einer Aktivität von Wirkstoffen in einer Lösung
KR102672900B1 (ko) * 2016-09-01 2024-06-10 (주)아모레퍼시픽 2,4-디클로로-a-(3,4-디하이드로-4-옥소-2(1H)-퀴나졸리닐리덴)-β-옥소-벤젠프로판니트릴을 포함하는 멜라닌 증진용 조성물
US11192893B2 (en) 2017-05-18 2021-12-07 The Rockefeller University Pyrazoloquinazolinone antitumor agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0995485A (ja) * 1995-03-16 1997-04-08 Takeda Chem Ind Ltd 複素環化合物、その製造法および剤
US20050080138A1 (en) * 1999-09-16 2005-04-14 Curis, Inc. Mediators of hedgehog signaling pathways, compositions and uses related thereto
AU2003225668A1 (en) * 2002-03-01 2003-09-16 Pintex Pharmaceutical, Inc. Pin1-modulating compounds and methods of use thereof
US20060052345A1 (en) * 2002-11-04 2006-03-09 Nps Pharmaceuticals, Inc. Quinazolinone compounds as calcilytics
EP2177189B1 (en) 2003-02-12 2015-11-04 The Procter and Gamble Company Absorbent core for an absorbent article
WO2007124171A2 (en) * 2006-04-20 2007-11-01 Massachusetts Institute Of Technology Compositions and methods for treating trinucleotide repeat disorders
AR062200A1 (es) * 2006-08-04 2008-10-22 Aeterna Zentaris Gmbh Derivados de antraceno y su uso para el tratamiento de emfermedades tumorales bengnas y malingnas
US8686102B2 (en) 2007-11-02 2014-04-01 Momentive Performance Materials Inc. Textiles treated with copolymers of epoxy compounds and amino silanes having enhanced wet-strength
US20090118421A1 (en) 2007-11-02 2009-05-07 Momentive Performance Materials Inc. Copolymer of epoxy compounds and amino silanes
US8119640B2 (en) 2008-02-12 2012-02-21 The Board Of Trustees Of The Leland Stanford Junior University Hedgehog pathway antagonists methods of use
EP2376495A4 (en) * 2008-12-08 2012-10-31 Vm Pharma Llc COMPOSITIONS OF PROTEIN RECEPTOR TYROSINE KINASE INHIBITORS

Also Published As

Publication number Publication date
AU2012207393A1 (en) 2013-08-08
US9145376B2 (en) 2015-09-29
EP2665712A1 (en) 2013-11-27
CA2824925A1 (en) 2012-07-26
US20130296349A1 (en) 2013-11-07
WO2012099916A1 (en) 2012-07-26
JP2014506565A (ja) 2014-03-17

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