IL22721A - Benzodiazepine derivatives and process for the manufacture thereof - Google Patents

Benzodiazepine derivatives and process for the manufacture thereof

Info

Publication number
IL22721A
IL22721A IL22721A IL2272165A IL22721A IL 22721 A IL22721 A IL 22721A IL 22721 A IL22721 A IL 22721A IL 2272165 A IL2272165 A IL 2272165A IL 22721 A IL22721 A IL 22721A
Authority
IL
Israel
Prior art keywords
formula
amino
solution
benzodiazepin
phenyl
Prior art date
Application number
IL22721A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL22721A publication Critical patent/IL22721A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F27—FURNACES; KILNS; OVENS; RETORTS
    • F27D—DETAILS OR ACCESSORIES OF FURNACES, KILNS, OVENS, OR RETORTS, IN SO FAR AS THEY ARE OF KINDS OCCURRING IN MORE THAN ONE KIND OF FURNACE
    • F27D11/00—Arrangement of elements for electric heating in or on furnaces
    • F27D11/08—Heating by electric discharge, e.g. arc discharge
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P10/00—Technologies related to metal processing
    • Y02P10/10—Reduction of greenhouse gas [GHG] emissions
    • Y02P10/143—Reduction of greenhouse gas [GHG] emissions of methane [CH4]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
IL22721A 1961-02-10 1965-01-04 Benzodiazepine derivatives and process for the manufacture thereof IL22721A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US8828561A 1961-02-10 1961-02-10
US11530961A 1961-06-07 1961-06-07
US33986164A 1964-01-24 1964-01-24
US412325A US3215688A (en) 1961-02-10 1964-11-19 Certain benzodiazepine compounds
US412335A US3262938A (en) 1961-02-10 1964-11-19 Carbocyclic substituted piperidyl dioxolanes
US416602A US3256289A (en) 1961-02-10 1964-12-07 Carbocyclic substituted piperidyl dioxanes

Publications (1)

Publication Number Publication Date
IL22721A true IL22721A (en) 1968-09-26

Family

ID=27557343

Family Applications (1)

Application Number Title Priority Date Filing Date
IL22721A IL22721A (en) 1961-02-10 1965-01-04 Benzodiazepine derivatives and process for the manufacture thereof

Country Status (10)

Country Link
US (3) US3262938A (sl)
BE (2) BE658797A (sl)
CH (5) CH405310A (sl)
DE (3) DE1545929A1 (sl)
FR (3) FR1812M (sl)
GB (3) GB971661A (sl)
IL (1) IL22721A (sl)
NL (1) NL141780B (sl)
NO (1) NO117366B (sl)
SE (3) SE315595B (sl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE661945A (sl) * 1964-04-01
US3464997A (en) * 1966-03-17 1969-09-02 Us Army Synthesis of 3-quinuclidinol
US3760077A (en) * 1969-02-18 1973-09-18 Cutter Lab Injectable compositions of the (plus)-optical isomer of the alpha racemate of 2-(2-ethyl-2-phenyl-1, -dioxolan-4-yl)piperidine and their use
US3856963A (en) * 1971-10-15 1974-12-24 Cutter Lab Use of injectable compositions of the ({30 )-optional isomer of the alpha racemate of 2-(2-ethyl-2-phenyl-1,3-dioxolan-4-yl) piperidine to control pain
US3879406A (en) * 1972-07-13 1975-04-22 Hoffmann La Roche Preparation of triazolobenzodiazepines
US4044016A (en) * 1975-01-13 1977-08-23 Hoffmann-La Roche Inc. Preparation of triazolo benzodiazepines and novel compounds
DE19714041A1 (de) * 1997-04-05 1998-10-08 Henkel Kgaa Phenonenketale
DE602005010264D1 (de) * 2004-08-10 2008-11-20 Merck Patent Gmbh Flüssigkristallverbindungen, flüssigkristallmedium und flüssigkristallanzeige
WO2006021304A1 (de) * 2004-08-24 2006-03-02 Basf Aktiengesellschaft Verfahren zur herstellung quartärer ammoniumverbindungen hoher reinheit
JP2008001596A (ja) * 2004-09-03 2008-01-10 Astellas Pharma Inc ナトリウムチャネル阻害剤

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2606909A (en) * 1947-08-01 1952-08-12 Univ Michigan Basic dioxolanes
US2606907A (en) * 1949-08-04 1952-08-12 Univ Michigan Basic dioxanes
DE1099540B (de) * 1954-09-10 1961-02-16 Bayer Ag Verfahren zur Herstellung von Kondensationsprodukten
FR1186192A (fr) * 1957-02-26 1959-08-17 Rhone Poulenc Sa Nouveaux pipéridyl-2 dioxolannes et leur préparation
US3070596A (en) * 1959-03-23 1962-12-25 Aerojet General Co 1, 1'-biaziridine compounds and the process of preparation
US3121075A (en) * 1961-10-20 1964-02-11 Hoffmann La Roche Aminobenzodiazepines

Also Published As

Publication number Publication date
CH460794A (de) 1968-08-15
NL6500594A (sl) 1965-07-26
GB1043049A (en) 1966-09-21
CH405310A (de) 1966-01-15
FR4166M (sl) 1966-05-16
DE1445558A1 (de) 1972-04-20
GB1077800A (en) 1967-08-02
DE1545929A1 (de) 1969-12-18
US3256289A (en) 1966-06-14
BE412325A (sl) 1900-01-01
US3262938A (en) 1966-07-26
GB971661A (en) 1964-09-30
CH460792A (de) 1968-08-15
DE1545713A1 (de) 1969-12-18
NL141780B (nl) 1974-04-16
FR1818M (sl) 1963-05-13
CH460774A (de) 1968-08-15
SE315595B (sl) 1969-10-06
CH446360A (de) 1967-11-15
DE1445558B2 (de) 1975-06-05
SE335134B (sl) 1971-05-17
FR1812M (sl) 1963-05-13
US3215688A (en) 1965-11-02
BE658797A (sl) 1965-07-26
DE1545714A1 (de) 1969-06-26
NO117366B (sl) 1969-08-04
SE335135B (sl) 1971-05-17

Similar Documents

Publication Publication Date Title
US3391138A (en) Certain 1-substituted-benzodiazepin-2-one compounds
IL22721A (en) Benzodiazepine derivatives and process for the manufacture thereof
US3431304A (en) 2 - aminoalkylamino-benzophenones-oximes and imines and the salts thereof
US3682892A (en) 7-hydroxy lower alkyl benzodiazepines
US3520877A (en) 3-carbonyl amino acetic acid ethyl ester substituted benzodiazepines
US3869448A (en) 2-Lower alkylsulfinyl-1H-1,4-benzodiazepines
US3812103A (en) 2,3-dihydro-1,4-benzodiazepines
US3644334A (en) 7-azido-benzodiazepines
US3925358A (en) 1-Lower alkyl-2-substituted-1,4-benzodiazepines
US3872089A (en) Substituted thienodiazepines
US3464978A (en) 1-substituted urea alkyl 1,2-dihydro-1,4-benzodiazepines and benzodiazepin - 2-ones
DE2238579A1 (de) Benzodiazepinderivate
US3450695A (en) Benzodiazepine compounds and methods for their production
US3801569A (en) 7-(1,1-difluoroalkyl)-1,4-benzodiazepines
US3703510A (en) 1-carboxyalkyl or 1-carboxyalkenyl-1,4-benzodiazepin-2-ones
US3825533A (en) N-carboxymethyl-n-substituted glycinate esters of 3-hydroxy-1,4-benzo-diazepin-2-ones
US3879406A (en) Preparation of triazolobenzodiazepines
IL28971A (en) 1,2,3,5-tetrahydropyrimido(1,2-a)(1,4)-and 1,2-dihydro-4h-imidazo-(1,2-a)(1,4)benzodiazepine derivatives and processes for the manufacture thereof
US3867370A (en) 2-LOWER ALKYSULFONYL-1H-1,4-benzodiazepines
US3696095A (en) (1,3) oxazino (3,2-d) (1,4) benzodiazepine derivatives and process for the preparation thereof
US3954728A (en) Preparation of triazolo benzodiazepines and novel compounds
US3868363A (en) 1H-5-phenyl-1,4-benzodiazepines
US3850948A (en) Certain 3a,4-dihydro-8-chloro-6-phenyl-thiazolo(3,2-h)-1,4-benzodiazepin-1(2h)-ones
US3795702A (en) 2-substituted-p-nitro-anilines
US3836521A (en) 2-lower alkylthio-1h-1,4-benzodiazepines