IL225617A0 - Compounds that are similar to cyclosporine - Google Patents
Compounds that are similar to cyclosporineInfo
- Publication number
- IL225617A0 IL225617A0 IL225617A IL22561713A IL225617A0 IL 225617 A0 IL225617 A0 IL 225617A0 IL 225617 A IL225617 A IL 225617A IL 22561713 A IL22561713 A IL 22561713A IL 225617 A0 IL225617 A0 IL 225617A0
- Authority
- IL
- Israel
- Prior art keywords
- cyclosporin analogs
- cyclosporin
- analogs
- Prior art date
Links
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Virology (AREA)
- Ophthalmology & Optometry (AREA)
- Analytical Chemistry (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Biotechnology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39244910P | 2010-10-12 | 2010-10-12 | |
| PCT/US2011/055791 WO2012051194A1 (en) | 2010-10-12 | 2011-10-11 | Cyclosporin analogs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL225617A0 true IL225617A0 (en) | 2013-06-27 |
Family
ID=44883784
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL225617A IL225617A0 (en) | 2010-10-12 | 2013-04-07 | Compounds that are similar to cyclosporine |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US20120088734A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2627664B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5805774B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20140026329A (cg-RX-API-DMAC7.html) |
| CN (1) | CN103328497A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2011316690C1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112013008864A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2814192A1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL225617A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2013004061A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2013119869A (cg-RX-API-DMAC7.html) |
| SG (1) | SG189880A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012051194A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9573978B2 (en) | 2010-08-12 | 2017-02-21 | S&T Global, Inc. | Cyclosporin derivatives for the treatment and prevention of a viral infection |
| WO2012051194A1 (en) * | 2010-10-12 | 2012-04-19 | Allergan, Inc. | Cyclosporin analogs |
| CN103261212A (zh) | 2010-10-12 | 2013-08-21 | 阿勒根公司 | 环孢菌素类似物 |
| US9890198B2 (en) * | 2010-12-03 | 2018-02-13 | S&T Global Inc. | Cyclosporin derivatives and uses thereof |
| AU2011342284C1 (en) * | 2010-12-15 | 2017-07-13 | Contravir Pharmaceuticals, Inc. | Cyclosporine analogue molecules modified at amino acid 1 and 3 |
| CN104487449A (zh) * | 2012-06-01 | 2015-04-01 | 阿勒根公司 | 环孢菌素a类似物 |
| GB201222455D0 (en) * | 2012-12-13 | 2013-01-30 | Perioc Ltd | Novel pharmaceutical formulations and their use in the treatment of periodontaldisease |
| WO2014138437A1 (en) | 2013-03-08 | 2014-09-12 | Allergan, Inc. | Steroid conjugates |
| WO2016112321A1 (en) | 2015-01-08 | 2016-07-14 | Allergan, Inc. | Cyclosporin derivatives wherein the mebmt sidechain has been cyclized |
| EP3277704A1 (en) | 2015-03-31 | 2018-02-07 | Allergan, Inc. | Cyclosporins modified on the mebmt sidechain by heterocyclic rings |
| JP2019518745A (ja) * | 2016-05-17 | 2019-07-04 | エス アンド ティー グローバル インク． | 新規シクロスポリン誘導体及びその使用 |
| US20180193003A1 (en) | 2016-12-07 | 2018-07-12 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| US11523772B2 (en) | 2016-12-14 | 2022-12-13 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with an immunosuppressant |
| US20230041197A1 (en) | 2018-06-20 | 2023-02-09 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| WO2021173474A1 (en) * | 2020-02-26 | 2021-09-02 | Bacainn Biotherapeutics, Ltd. | Cyclosporine compositions and methods of use |
| CN113173974B (zh) * | 2021-03-18 | 2024-09-06 | 北京大学深圳研究生院 | 环孢素衍生物的合成方法 |
| WO2024254480A2 (en) * | 2023-06-08 | 2024-12-12 | Hepion Pharmaceuticals, Inc. | Solid state forms of rencofilstat |
| CN118834148B (zh) * | 2024-09-20 | 2025-01-21 | 天津凯莱英制药有限公司 | 一种l-青霉胺的制备方法 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0194972B1 (en) | 1985-03-11 | 1992-07-29 | Sandoz Ag | Novel cyclosporins |
| US4649047A (en) * | 1985-03-19 | 1987-03-10 | University Of Georgia Research Foundation, Inc. | Ophthalmic treatment by topical administration of cyclosporin |
| US4839342A (en) | 1987-09-03 | 1989-06-13 | University Of Georgia Research Foundation, Inc. | Method of increasing tear production by topical administration of cyclosporin |
| US5474979A (en) * | 1994-05-17 | 1995-12-12 | Allergan, Inc. | Nonirritating emulsions for sensitive tissue |
| FR2757521B1 (fr) | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2757522B1 (fr) | 1996-12-24 | 1999-01-29 | Rhone Poulenc Rorer Sa | Derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2762843B1 (fr) | 1997-04-30 | 1999-12-10 | Rhone Poulenc Rorer Sa | Nouveaux derives de cyclosporine, leur preparation et les compositions pharmaceutiques qui les contiennent |
| HUP0102833A3 (en) * | 1998-06-12 | 2002-03-28 | Chem Ag C | Cyclosporins, process for preparation thereof and their use |
| US6254860B1 (en) * | 1999-04-13 | 2001-07-03 | Allergan Sales, Inc. | Ocular treatment using cyclosporin-A derivatives |
| US20050059583A1 (en) * | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
| US7676680B2 (en) | 2005-07-08 | 2010-03-09 | Morgan Stanley | Systems and methods for distributing private placement documents |
| US7288520B2 (en) | 2005-07-13 | 2007-10-30 | Allergan, Inc. | Cyclosporin compositions |
| DK2023918T3 (da) | 2006-05-19 | 2011-04-26 | Scynexis Inc | Cyclosporiner til behandlingen og forebyggelse af okulære lidelser |
| CN101130058B (zh) * | 2006-08-23 | 2011-10-05 | 华北制药集团新药研究开发有限责任公司 | 一种环孢菌素a眼用乳剂及其制备方法 |
| CN101687013A (zh) * | 2007-05-04 | 2010-03-31 | 阿勒根公司 | 环孢菌素在治疗具有人工晶状体的患者中的用途 |
| BRPI0915552A2 (pt) * | 2008-07-10 | 2017-06-20 | Allergan Inc | derivados de ciclosporina, seu uso e sua composição farmacêutica |
| WO2012003077A1 (en) * | 2010-07-02 | 2012-01-05 | Exxonmobil Upstream Research Company | Low emission triple-cycle power generation systems and methods |
| US8902844B2 (en) | 2010-07-06 | 2014-12-02 | Lg Electronics Inc. | Method and device for allocating wireless resources for a machine type communication device in a wireless communication system |
| WO2012051194A1 (en) * | 2010-10-12 | 2012-04-19 | Allergan, Inc. | Cyclosporin analogs |
| US9890198B2 (en) | 2010-12-03 | 2018-02-13 | S&T Global Inc. | Cyclosporin derivatives and uses thereof |
| ES2625502T3 (es) * | 2010-12-03 | 2017-07-19 | S&T Global Inc | Nuevos derivados de ciclosporina para el tratamiento y prevención de una infección vírica |
| CN103987399A (zh) * | 2011-08-19 | 2014-08-13 | 美国科技环球有限公司 | 用于治疗和预防病毒感染的新型环孢菌素衍生物 |
-
2011
- 2011-10-11 WO PCT/US2011/055791 patent/WO2012051194A1/en not_active Ceased
- 2011-10-11 KR KR1020137012145A patent/KR20140026329A/ko not_active Withdrawn
- 2011-10-11 EP EP11770985.7A patent/EP2627664B1/en not_active Not-in-force
- 2011-10-11 CA CA2814192A patent/CA2814192A1/en not_active Abandoned
- 2011-10-11 BR BR112013008864A patent/BR112013008864A2/pt not_active Application Discontinuation
- 2011-10-11 RU RU2013119869/04A patent/RU2013119869A/ru not_active Application Discontinuation
- 2011-10-11 SG SG2013027339A patent/SG189880A1/en unknown
- 2011-10-11 CN CN2011800596461A patent/CN103328497A/zh active Pending
- 2011-10-11 MX MX2013004061A patent/MX2013004061A/es unknown
- 2011-10-11 JP JP2013533942A patent/JP5805774B2/ja not_active Expired - Fee Related
- 2011-10-11 AU AU2011316690A patent/AU2011316690C1/en not_active Ceased
- 2011-10-11 US US13/270,964 patent/US20120088734A1/en not_active Abandoned
-
2013
- 2013-04-07 IL IL225617A patent/IL225617A0/en unknown
-
2014
- 2014-11-06 US US14/534,677 patent/US9493511B2/en active Active
-
2015
- 2015-09-02 JP JP2015173082A patent/JP6250608B2/ja not_active Expired - Fee Related
-
2016
- 2016-10-11 US US15/290,171 patent/US10065992B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2011316690B2 (en) | 2016-07-07 |
| EP2627664B1 (en) | 2018-04-04 |
| JP6250608B2 (ja) | 2017-12-20 |
| US20120088734A1 (en) | 2012-04-12 |
| WO2012051194A1 (en) | 2012-04-19 |
| AU2011316690A1 (en) | 2013-05-02 |
| SG189880A1 (en) | 2013-06-28 |
| JP2016029050A (ja) | 2016-03-03 |
| KR20140026329A (ko) | 2014-03-05 |
| US10065992B2 (en) | 2018-09-04 |
| CA2814192A1 (en) | 2012-04-19 |
| CN103328497A (zh) | 2013-09-25 |
| JP5805774B2 (ja) | 2015-11-10 |
| EP2627664A1 (en) | 2013-08-21 |
| MX2013004061A (es) | 2013-07-22 |
| BR112013008864A2 (pt) | 2016-06-28 |
| US9493511B2 (en) | 2016-11-15 |
| JP2013540776A (ja) | 2013-11-07 |
| US20150065433A1 (en) | 2015-03-05 |
| AU2011316690C1 (en) | 2017-01-19 |
| US20170029469A1 (en) | 2017-02-02 |
| RU2013119869A (ru) | 2014-11-20 |
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