IL213390A0 - Novel semi-synthetic glycopeptides as antibacterial agents - Google Patents

Novel semi-synthetic glycopeptides as antibacterial agents

Info

Publication number
IL213390A0
IL213390A0 IL213390A IL21339011A IL213390A0 IL 213390 A0 IL213390 A0 IL 213390A0 IL 213390 A IL213390 A IL 213390A IL 21339011 A IL21339011 A IL 21339011A IL 213390 A0 IL213390 A0 IL 213390A0
Authority
IL
Israel
Prior art keywords
antibacterial agents
novel semi
synthetic glycopeptides
glycopeptides
synthetic
Prior art date
Application number
IL213390A
Other languages
English (en)
Original Assignee
Lead Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2008/085716 external-priority patent/WO2009085562A1/en
Application filed by Lead Therapeutics Inc filed Critical Lead Therapeutics Inc
Publication of IL213390A0 publication Critical patent/IL213390A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K9/00Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL213390A 2008-12-05 2011-06-05 Novel semi-synthetic glycopeptides as antibacterial agents IL213390A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/US2008/085716 WO2009085562A1 (en) 2007-12-26 2008-12-05 Novel semi-synthetic glycopeptides as antibacterial agents
US22016709P 2009-06-24 2009-06-24
PCT/US2009/055633 WO2010065174A1 (en) 2008-12-05 2009-09-01 Novel semi-synthetic glycopeptides as antibacterial agents

Publications (1)

Publication Number Publication Date
IL213390A0 true IL213390A0 (en) 2011-07-31

Family

ID=41203726

Family Applications (1)

Application Number Title Priority Date Filing Date
IL213390A IL213390A0 (en) 2008-12-05 2011-06-05 Novel semi-synthetic glycopeptides as antibacterial agents

Country Status (12)

Country Link
US (1) US20110015119A1 (https=)
EP (1) EP2373694A1 (https=)
JP (1) JP2012510999A (https=)
KR (1) KR20110099028A (https=)
CN (1) CN102307903A (https=)
AR (1) AR075354A1 (https=)
AU (1) AU2009322925A1 (https=)
CA (1) CA2745446A1 (https=)
GB (1) GB2465863A (https=)
IL (1) IL213390A0 (https=)
TW (1) TW201021805A (https=)
WO (1) WO2010065174A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011140009A1 (en) * 2010-05-04 2011-11-10 Biomarin Pharmaceutical Inc. Methods of using semi-synthetic glycopeptides as antibacterial agents
CN107325159A (zh) 2016-04-29 2017-11-07 中国科学院上海药物研究所 一类万古霉素衍生物、其制备方法、药物组合物和用途
GB2577420B (en) 2017-05-22 2022-07-06 Insmed Inc Glycopeptide derivative compounds and uses thereof
CN109422800A (zh) * 2017-08-22 2019-03-05 复旦大学 抗革兰氏阳性菌季铵盐糖肽类化合物及其药用用途
CN111793076B (zh) * 2020-06-05 2021-10-12 华北制药河北华民药业有限责任公司 一种注射用硫酸头孢匹罗的制备方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0662674B2 (ja) * 1985-01-11 1994-08-17 三共株式会社 抗生物質クロロポリスポリンbまたはc
US4643987A (en) * 1985-08-14 1987-02-17 Eli Lilly And Company Modified glycopeptides
NZ509165A (en) * 1998-07-14 2003-08-29 Univ Princeton Glycopeptide antobiotics, combinatorial libraries of glycopeptide antibiotics and methods of producing same
DE69908819T2 (de) * 1998-12-23 2004-05-06 Theravance, Inc., South San Francisco Glycopeptid-derivate und pharmazeutische zusammensetzungen, die sie enthalten
AU4054900A (en) * 1999-04-02 2000-10-23 Advanced Medicine East, Inc. Desleucyl glycopeptide antibiotics and methods of making same
MXPA02006029A (es) * 1999-12-15 2004-08-23 Cubist Pharm Inc Lipopeptidos novedosos como agentes antibacterianos.
US6397405B1 (en) * 2000-04-11 2002-06-04 Thetford Corporation Flush toilet for RV's and boats
US6770621B2 (en) * 2000-05-02 2004-08-03 Theravance, Inc. Polyacid glycopeptide derivatives
UA75083C2 (uk) * 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
US6620781B2 (en) * 2000-06-22 2003-09-16 Theravance, Inc. Glycopeptide carboxy-saccharide derivatives
US20030008812A1 (en) * 2001-02-02 2003-01-09 Christensen Burton G. Glycopeptide derivatives
TWI233932B (en) * 2001-08-24 2005-06-11 Theravance Inc Process for purifying glycopeptide phosphonate derivatives
US7521418B2 (en) * 2003-05-27 2009-04-21 Theravance, Inc. Use of a polyene macrolide antifungal agent in combination with a glycopeptide antibacterial agent
CA2588285A1 (en) * 2004-11-29 2006-06-01 National University Corporation Nagoya University Glycopeptide antibiotic monomer derivatives
US7632918B2 (en) * 2005-02-28 2009-12-15 Novartis Vaccines And Diagnostics, Inc. Semi-synthetic glycopeptides with antibiotic activity
US20070185015A1 (en) * 2005-02-28 2007-08-09 Chiron Corporation and North China Pharmaceutical Corporation Semi-synthetic desmethyl-vancomycin-based glycopeptides with antibiotic activity
US7368422B2 (en) * 2005-02-28 2008-05-06 Novartis Vaccines And Diagnostics Inc. Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity
US8236926B2 (en) * 2006-09-06 2012-08-07 Wisconsin Alumni Research Foundation Rapid glycopeptide optimization via neoglycosylation
WO2008075684A1 (ja) * 2006-12-19 2008-06-26 Shionogi & Co., Ltd. グリコペプチド抗生物質誘導体
GB2449156B8 (en) * 2007-05-08 2010-06-02 Lead Therapeutics Inc Semi-synthetic glycopeptides with antibacterial activity.
US20090062268A1 (en) * 2007-08-27 2009-03-05 Lead Therapeutics, Inc. Novel inhibitors of poly(adp-ribose)polymerase (parp)
CN101959849A (zh) * 2007-12-26 2011-01-26 利德治疗公司 作为抗菌剂的新型半合成糖肽
US20100105607A1 (en) * 2008-10-24 2010-04-29 Lead Therapeutics, Inc. Novel semi-synthetic glycopeptides as antibacterial agents
US20100216699A1 (en) * 2009-02-09 2010-08-26 Lead Therapeutics, Inc. Semi-synthetic glycopeptides having antibacterial activity

Also Published As

Publication number Publication date
AU2009322925A1 (en) 2011-06-30
GB0915258D0 (en) 2009-10-07
KR20110099028A (ko) 2011-09-05
CA2745446A1 (en) 2010-06-10
AR075354A1 (es) 2011-03-30
US20110015119A1 (en) 2011-01-20
GB2465863A (en) 2010-06-09
JP2012510999A (ja) 2012-05-17
TW201021805A (en) 2010-06-16
EP2373694A1 (en) 2011-10-12
WO2010065174A1 (en) 2010-06-10
CN102307903A (zh) 2012-01-04

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