IL205278A0 - Therapeutic substituted lactams - Google Patents
Therapeutic substituted lactamsInfo
- Publication number
- IL205278A0 IL205278A0 IL205278A IL20527810A IL205278A0 IL 205278 A0 IL205278 A0 IL 205278A0 IL 205278 A IL205278 A IL 205278A IL 20527810 A IL20527810 A IL 20527810A IL 205278 A0 IL205278 A0 IL 205278A0
- Authority
- IL
- Israel
- Prior art keywords
- substituted lactams
- therapeutic substituted
- therapeutic
- lactams
- substituted
- Prior art date
Links
- 150000003951 lactams Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98191807P | 2007-10-23 | 2007-10-23 | |
| US98483807P | 2007-11-02 | 2007-11-02 | |
| PCT/US2008/080063 WO2009055289A2 (en) | 2007-10-23 | 2008-10-16 | Therapeutic substituted lactams |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL205278A0 true IL205278A0 (en) | 2010-12-30 |
Family
ID=40521508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL205278A IL205278A0 (en) | 2007-10-23 | 2010-04-22 | Therapeutic substituted lactams |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7998998B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2215084B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5410438B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20100086485A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101868455B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008317107B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0820410A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2703479C (cg-RX-API-DMAC7.html) |
| IL (1) | IL205278A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2010004487A (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ585103A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009055289A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2155733T3 (da) * | 2007-05-23 | 2012-10-29 | Allergan Inc | Cykliske lactamer til behandling af glaukom eller forhøjet intraokulært tryk |
| US9440919B2 (en) | 2012-07-19 | 2016-09-13 | Cayman Chemical Company, Inc. | Difluorolactam compositions for EP4-mediated osteo related diseases and conditions |
| CN104583204A (zh) * | 2012-08-21 | 2015-04-29 | 阿勒根公司 | 用于合成取代的γ内酰胺的方法 |
| CN103665043B (zh) | 2012-08-30 | 2017-11-10 | 江苏豪森药业集团有限公司 | 一种替诺福韦前药及其在医药上的应用 |
| WO2014144500A2 (en) | 2013-03-15 | 2014-09-18 | Cayman Chemical Company, Inc. | Methods of synthesizing a difluorolactam analog |
| JP6317807B2 (ja) | 2013-03-15 | 2018-04-25 | ケイマン ケミカル カンパニー， インコーポレーテッド | Ｅｐ４媒介性の疾病及び病態の治療に使用するためのｅｐ４受容体選択性アゴニストとしてのラクタム化合物 |
| US9676712B2 (en) | 2013-03-15 | 2017-06-13 | Cayman Chemical Company, Inc. | Lactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions |
| AU2014290512A1 (en) | 2013-07-19 | 2015-11-12 | Cayman Chemical Company, Inc. | Methods, systems, and compositions for promoting bone growth |
| US9540357B1 (en) | 2014-07-31 | 2017-01-10 | Allergan, Inc. | 15-aryl prostaglandins as EP4 agonists, and methods of use thereof |
| KR102877633B1 (ko) | 2021-09-01 | 2025-10-28 | 에스케이하이닉스 주식회사 | 반도체 웨이퍼의 불량 분석 방법 및 그 시스템 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4035961A1 (de) * | 1990-11-02 | 1992-05-07 | Thomae Gmbh Dr K | Cyclische iminoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| BR0211201A (pt) * | 2001-07-16 | 2004-07-13 | Hoffmann La Roche | Composto, processo para a preparação desse composto, sua utilização, composição farmacêutica que compreende o mesmo e método para o tratamento de uma enfermidade em um mamìfero |
| CN103265477B (zh) * | 2003-02-26 | 2017-01-11 | 苏根公司 | 作为蛋白激酶抑制剂的氨基杂芳基化合物 |
| EA011097B1 (ru) * | 2004-05-07 | 2008-12-30 | Янссен Фармацевтика Н.В. | Производные пирролидин-2-она и пиперидин-2-она, используемые в качестве ингибиторов 11-бета-гидроксистероид-дегидрогеназы |
| WO2007108360A1 (ja) * | 2006-03-17 | 2007-09-27 | Intellectual Property Bank Corp. | 細径盲管を用いた表面増強ラマン散乱による物質検知方法および物質検知装置、複数物質検知デバイス、盲管 |
| MX2009008734A (es) * | 2007-02-15 | 2009-08-25 | Allergan Inc | Gamma lactamas para el tratamiento de glaucoma o hipertension intraocular. |
-
2008
- 2008-10-16 CN CN2008801167781A patent/CN101868455B/zh not_active Expired - Fee Related
- 2008-10-16 US US12/739,676 patent/US7998998B2/en active Active
- 2008-10-16 MX MX2010004487A patent/MX2010004487A/es active IP Right Grant
- 2008-10-16 JP JP2010531133A patent/JP5410438B2/ja not_active Expired - Fee Related
- 2008-10-16 AU AU2008317107A patent/AU2008317107B2/en not_active Ceased
- 2008-10-16 KR KR1020107010956A patent/KR20100086485A/ko not_active Ceased
- 2008-10-16 WO PCT/US2008/080063 patent/WO2009055289A2/en not_active Ceased
- 2008-10-16 NZ NZ585103A patent/NZ585103A/en not_active IP Right Cessation
- 2008-10-16 CA CA2703479A patent/CA2703479C/en not_active Expired - Fee Related
- 2008-10-16 EP EP08842624.2A patent/EP2215084B1/en not_active Not-in-force
- 2008-10-16 BR BRPI0820410-1A patent/BRPI0820410A2/pt not_active IP Right Cessation
-
2010
- 2010-04-22 IL IL205278A patent/IL205278A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ585103A (en) | 2012-04-27 |
| KR20100086485A (ko) | 2010-07-30 |
| RU2010120015A (ru) | 2011-11-27 |
| US20100292293A1 (en) | 2010-11-18 |
| JP2011500818A (ja) | 2011-01-06 |
| MX2010004487A (es) | 2010-05-05 |
| US7998998B2 (en) | 2011-08-16 |
| CN101868455A (zh) | 2010-10-20 |
| JP5410438B2 (ja) | 2014-02-05 |
| CN101868455B (zh) | 2013-11-13 |
| AU2008317107B2 (en) | 2013-09-12 |
| BRPI0820410A2 (pt) | 2015-05-19 |
| WO2009055289A2 (en) | 2009-04-30 |
| WO2009055289A3 (en) | 2009-06-11 |
| CA2703479A1 (en) | 2009-04-30 |
| EP2215084B1 (en) | 2016-09-28 |
| EP2215084A2 (en) | 2010-08-11 |
| AU2008317107A1 (en) | 2009-04-30 |
| CA2703479C (en) | 2017-08-22 |
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