IL199216A - Monoclonal Antibodies Against 3angptl, Pharmaceuticals Containing Them and Their Uses - Google Patents

Monoclonal Antibodies Against 3angptl, Pharmaceuticals Containing Them and Their Uses

Info

Publication number
IL199216A
IL199216A IL199216A IL19921609A IL199216A IL 199216 A IL199216 A IL 199216A IL 199216 A IL199216 A IL 199216A IL 19921609 A IL19921609 A IL 19921609A IL 199216 A IL199216 A IL 199216A
Authority
IL
Israel
Prior art keywords
same
pharmaceutical compositions
monoclonal antibodies
antibodies against
against angptl3
Prior art date
Application number
IL199216A
Other languages
English (en)
Hebrew (he)
Original Assignee
Lexicon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lexicon Pharmaceuticals Inc filed Critical Lexicon Pharmaceuticals Inc
Publication of IL199216A publication Critical patent/IL199216A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL199216A 2006-12-08 2009-06-07 Monoclonal Antibodies Against 3angptl, Pharmaceuticals Containing Them and Their Uses IL199216A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US87383406P 2006-12-08 2006-12-08
PCT/US2007/025080 WO2008073300A2 (en) 2006-12-08 2007-12-06 Monoclonal antibodies against angptl3

Publications (1)

Publication Number Publication Date
IL199216A true IL199216A (en) 2016-02-29

Family

ID=39512267

Family Applications (1)

Application Number Title Priority Date Filing Date
IL199216A IL199216A (en) 2006-12-08 2009-06-07 Monoclonal Antibodies Against 3angptl, Pharmaceuticals Containing Them and Their Uses

Country Status (21)

Country Link
US (2) US7935796B2 (enExample)
EP (1) EP2121751B1 (enExample)
JP (1) JP5484063B2 (enExample)
KR (1) KR101503937B1 (enExample)
CN (1) CN101855241B (enExample)
AR (1) AR064205A1 (enExample)
AU (1) AU2007332855B2 (enExample)
BR (1) BRPI0720218A2 (enExample)
CA (1) CA2672049C (enExample)
DK (1) DK2121751T3 (enExample)
EA (1) EA019661B1 (enExample)
ES (1) ES2618830T3 (enExample)
HU (1) HUE033960T2 (enExample)
IL (1) IL199216A (enExample)
MX (1) MX2009006082A (enExample)
NO (1) NO20092215L (enExample)
PL (1) PL2121751T3 (enExample)
PT (1) PT2121751T (enExample)
TW (1) TW200846364A (enExample)
WO (1) WO2008073300A2 (enExample)
ZA (1) ZA200904022B (enExample)

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US9149492B2 (en) 2008-10-08 2015-10-06 Trustees Of Dartmouth College Method for selectively inhibiting ACAT1 in the treatment of alzheimer's disease
WO2010042292A1 (en) * 2008-10-08 2010-04-15 Trustees Of Dartmouth College Method for selectively inhibiting the activity of acat1 in the treatment of alzheimer's disease
US9388414B2 (en) 2008-10-08 2016-07-12 Trustees Of Dartmouth College Method for selectively inhibiting ACAT1 in the treatment of neurodegenerative diseases
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CN101852805B (zh) * 2009-03-31 2015-04-01 浙江大学 Angptl3作为卵巢癌的诊断标记物的用途
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Also Published As

Publication number Publication date
EA019661B1 (ru) 2014-05-30
PT2121751T (pt) 2017-04-18
WO2008073300A2 (en) 2008-06-19
EP2121751A2 (en) 2009-11-25
ES2618830T3 (es) 2017-06-22
AU2007332855B2 (en) 2012-08-16
EA200970556A1 (ru) 2010-04-30
CA2672049C (en) 2016-05-10
WO2008073300A3 (en) 2009-12-23
AR064205A1 (es) 2009-03-18
CN101855241B (zh) 2013-11-06
NO20092215L (no) 2009-08-19
HUE033960T2 (en) 2018-01-29
DK2121751T3 (en) 2017-04-24
CN101855241A (zh) 2010-10-06
US7935796B2 (en) 2011-05-03
AU2007332855A1 (en) 2008-06-19
BRPI0720218A2 (pt) 2013-12-24
US20080177045A1 (en) 2008-07-24
PL2121751T3 (pl) 2017-07-31
MX2009006082A (es) 2009-08-18
EP2121751A4 (en) 2012-01-11
CA2672049A1 (en) 2008-06-19
ZA200904022B (en) 2010-08-25
EP2121751B1 (en) 2017-01-25
US8742075B2 (en) 2014-06-03
JP2010512320A (ja) 2010-04-22
US20110243948A1 (en) 2011-10-06
TW200846364A (en) 2008-12-01
KR20090088925A (ko) 2009-08-20
KR101503937B1 (ko) 2015-03-18
JP5484063B2 (ja) 2014-05-07

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