IL197295A0 - Pharmaceutical composition comprising a plurality of mini-tablets comprising a factor xa inhibitor - Google Patents
Pharmaceutical composition comprising a plurality of mini-tablets comprising a factor xa inhibitorInfo
- Publication number
- IL197295A0 IL197295A0 IL197295A IL19729509A IL197295A0 IL 197295 A0 IL197295 A0 IL 197295A0 IL 197295 A IL197295 A IL 197295A IL 19729509 A IL19729509 A IL 19729509A IL 197295 A0 IL197295 A0 IL 197295A0
- Authority
- IL
- Israel
- Prior art keywords
- mini
- tablets
- inhibitor
- factor
- pharmaceutical composition
- Prior art date
Links
- 229940123583 Factor Xa inhibitor Drugs 0.000 title 1
- 239000008185 minitablet Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82531406P | 2006-09-12 | 2006-09-12 | |
| PCT/EP2007/059443 WO2008031782A1 (en) | 2006-09-12 | 2007-09-10 | Pharmaceutical composition comprising a plurality of mini-tablets comprising a factor xa inhibitor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL197295A0 true IL197295A0 (en) | 2009-12-24 |
Family
ID=38835794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL197295A IL197295A0 (en) | 2006-09-12 | 2009-02-26 | Pharmaceutical composition comprising a plurality of mini-tablets comprising a factor xa inhibitor |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20090285887A1 (enExample) |
| EP (1) | EP2061439A1 (enExample) |
| JP (1) | JP2010502762A (enExample) |
| KR (1) | KR20090052346A (enExample) |
| CN (1) | CN101516355A (enExample) |
| AR (1) | AR062721A1 (enExample) |
| AU (1) | AU2007296311A1 (enExample) |
| BR (1) | BRPI0716234A2 (enExample) |
| CA (1) | CA2662542A1 (enExample) |
| CL (1) | CL2007002618A1 (enExample) |
| EA (1) | EA200970267A1 (enExample) |
| IL (1) | IL197295A0 (enExample) |
| MX (1) | MX2009002669A (enExample) |
| PE (1) | PE20080661A1 (enExample) |
| TW (1) | TW200824723A (enExample) |
| WO (1) | WO2008031782A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2489659T3 (pl) | 2004-06-24 | 2018-06-29 | Vertex Pharma | Modulatory transporterów posiadających kasetę wiążącą atp |
| PT1993360T (pt) | 2005-12-28 | 2017-05-25 | Vertex Pharma | Formas sólidas de n-[2,4-bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-di-hidro-4-oxoquinolina-3-carboxamida |
| US12458635B2 (en) | 2008-08-13 | 2025-11-04 | Vertex Pharmaceuticals Incorporated | Pharmaceutical composition and administrations thereof |
| US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
| EP3330255B1 (en) | 2009-03-20 | 2020-12-09 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
| SMT202000093T1 (it) | 2009-06-16 | 2020-03-13 | Pfizer | Forme di dosaggio di apixaban |
| WO2010151745A1 (en) * | 2009-06-25 | 2010-12-29 | Elite Laboratories, Inc. | Oral dosage forms |
| SI3246021T1 (sl) * | 2010-02-25 | 2020-03-31 | Bristol-Myers Squibb Holdings Ireland Unlimited Company | Formulacije apiksabana |
| AU2015271995A1 (en) * | 2010-02-25 | 2016-01-21 | Bristol-Myers Squibb Holdings Ireland | Apixaban formulations |
| RU2013113627A (ru) * | 2010-08-27 | 2014-10-10 | Вертекс Фармасьютикалз Инкорпорейтед | Фармацевтическая композиция и ее введения |
| MX370873B (es) | 2010-10-15 | 2020-01-08 | Brain Sentinel Inc | Metodo y aparato para detectar convulsiones. |
| EP2554159A1 (en) * | 2011-08-04 | 2013-02-06 | ratiopharm GmbH | Dosage forms comprising apixaban and content uniformity enhancer |
| IL311180A (en) | 2012-02-27 | 2024-04-01 | Vertex Pharma | Pharmaceutical preparations containing a solid dispersion of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide and uses thereof |
| KR101378973B1 (ko) * | 2012-04-13 | 2014-03-28 | 한미약품 주식회사 | 구형에 가까운 형태의 다중 투여 단위 정제를 포함하는 경질 캡슐 복합 제형 및 이의 제조방법 |
| WO2013174498A1 (en) * | 2012-05-24 | 2013-11-28 | Ratiopharm Gmbh | Dosage forms comprising apixaban and matrix former |
| WO2014033077A1 (en) | 2012-08-28 | 2014-03-06 | Dsm Sinochem Pharmaceuticals Netherlands B.V. | Composition comprising an antibiotic and a beta-lactamase inhibitor, wherein at| least one of them is in the form of mini-tablets |
| CN107250113B (zh) | 2014-10-07 | 2019-03-29 | 弗特克斯药品有限公司 | 囊性纤维化跨膜传导调节蛋白的调节剂的共晶 |
| US20190046449A1 (en) * | 2016-02-25 | 2019-02-14 | Mylan Inc. | A unique high-shear granulation process for improved bioavailability of rivaroxaban |
| GB201721065D0 (en) * | 2017-12-15 | 2018-01-31 | Ondosis Ab | Delivery device for drug pellets |
| KR20190130411A (ko) | 2018-05-14 | 2019-11-22 | 신일제약주식회사 | 아픽사반 약제학적 제제 및 그의 제조방법 |
| WO2025150072A1 (en) * | 2024-01-13 | 2025-07-17 | Pulse Pharmaceuticals Pvt Ltd | A stable oral pro-dispersion formulation and implementations thereof |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60038097T2 (de) * | 1999-02-22 | 2009-02-12 | Merrion Research I Ltd. | Feste orale dosierungsform enthaltend einen resorptionsverstärker |
| WO2000048589A1 (en) * | 1999-02-22 | 2000-08-24 | Emisphere Holdings, Inc. | Solid oral dosage form containing heparin or a heparinoid in combination with a carrier |
| US6794412B1 (en) * | 1999-03-11 | 2004-09-21 | Bristol-Myers Squibb Pharma Company | Treatment of thrombosis by combined use of a factor Xa inhibitor and aspirin |
| GB0114004D0 (en) * | 2001-06-08 | 2001-08-01 | Glaxo Group Ltd | Chemical compounds |
| AR040680A1 (es) * | 2002-07-25 | 2005-04-13 | Pharmacia Corp | Composicion de tabletas de liberacion sostenida |
| KR20040076203A (ko) * | 2003-02-24 | 2004-08-31 | 주식회사 엘지생명과학 | 음식물-약물 상호작용을 방지하기 위한 경구 투여용약제학적 조성물 및 방법 |
| DE102004062475A1 (de) * | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
-
2007
- 2007-09-10 AR ARP070103983A patent/AR062721A1/es unknown
- 2007-09-10 PE PE2007001213A patent/PE20080661A1/es not_active Application Discontinuation
- 2007-09-10 US US12/440,740 patent/US20090285887A1/en not_active Abandoned
- 2007-09-10 AU AU2007296311A patent/AU2007296311A1/en not_active Abandoned
- 2007-09-10 JP JP2009527796A patent/JP2010502762A/ja not_active Withdrawn
- 2007-09-10 EA EA200970267A patent/EA200970267A1/ru unknown
- 2007-09-10 EP EP07803361A patent/EP2061439A1/en not_active Withdrawn
- 2007-09-10 CN CNA2007800338980A patent/CN101516355A/zh active Pending
- 2007-09-10 WO PCT/EP2007/059443 patent/WO2008031782A1/en not_active Ceased
- 2007-09-10 CL CL200702618A patent/CL2007002618A1/es unknown
- 2007-09-10 MX MX2009002669A patent/MX2009002669A/es not_active Application Discontinuation
- 2007-09-10 KR KR1020097005035A patent/KR20090052346A/ko not_active Withdrawn
- 2007-09-10 TW TW096133641A patent/TW200824723A/zh unknown
- 2007-09-10 CA CA002662542A patent/CA2662542A1/en not_active Abandoned
- 2007-09-10 BR BRPI0716234-0A patent/BRPI0716234A2/pt not_active IP Right Cessation
-
2009
- 2009-02-26 IL IL197295A patent/IL197295A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CL2007002618A1 (es) | 2008-03-14 |
| CN101516355A (zh) | 2009-08-26 |
| EP2061439A1 (en) | 2009-05-27 |
| WO2008031782A1 (en) | 2008-03-20 |
| TW200824723A (en) | 2008-06-16 |
| EA200970267A1 (ru) | 2009-08-28 |
| AU2007296311A1 (en) | 2008-03-20 |
| KR20090052346A (ko) | 2009-05-25 |
| JP2010502762A (ja) | 2010-01-28 |
| BRPI0716234A2 (pt) | 2013-10-15 |
| CA2662542A1 (en) | 2008-03-20 |
| AR062721A1 (es) | 2008-11-26 |
| MX2009002669A (es) | 2009-03-24 |
| PE20080661A1 (es) | 2008-06-12 |
| US20090285887A1 (en) | 2009-11-19 |
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