IL191271A - Pharmaceuticals for the treatment of dry eye conditions containing adenocin 3a receptor agonist - Google Patents
Pharmaceuticals for the treatment of dry eye conditions containing adenocin 3a receptor agonistInfo
- Publication number
- IL191271A IL191271A IL191271A IL19127108A IL191271A IL 191271 A IL191271 A IL 191271A IL 191271 A IL191271 A IL 191271A IL 19127108 A IL19127108 A IL 19127108A IL 191271 A IL191271 A IL 191271A
- Authority
- IL
- Israel
- Prior art keywords
- dry eye
- adenosine
- meca
- eye
- iodobenzyl
- Prior art date
Links
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- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL191271A IL191271A (en) | 2006-01-27 | 2008-05-06 | Pharmaceuticals for the treatment of dry eye conditions containing adenocin 3a receptor agonist |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76250606P | 2006-01-27 | 2006-01-27 | |
| PCT/IL2006/000130 WO2007086044A1 (en) | 2006-01-27 | 2006-02-01 | Adenosine a3 receptor agonists for the treatment of dry eye disorders |
| IL191271A IL191271A (en) | 2006-01-27 | 2008-05-06 | Pharmaceuticals for the treatment of dry eye conditions containing adenocin 3a receptor agonist |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL191271A0 IL191271A0 (en) | 2009-08-03 |
| IL191271A true IL191271A (en) | 2014-03-31 |
Family
ID=36794417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL191271A IL191271A (en) | 2006-01-27 | 2008-05-06 | Pharmaceuticals for the treatment of dry eye conditions containing adenocin 3a receptor agonist |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1976494A1 (pt) |
| JP (2) | JP5185139B2 (pt) |
| KR (1) | KR101037095B1 (pt) |
| CN (1) | CN101365430B (pt) |
| AU (1) | AU2006336834B2 (pt) |
| BR (1) | BRPI0621052A2 (pt) |
| CA (1) | CA2622975C (pt) |
| IL (1) | IL191271A (pt) |
| WO (1) | WO2007086044A1 (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE034474T2 (en) | 2007-03-14 | 2018-02-28 | Can Fite Biopharma Ltd | Method for the synthesis of IB-meca |
| IL184620A0 (en) * | 2007-07-15 | 2008-01-20 | Can Fite Biopharma Ltd | Composition for the treatment of inflammation |
| AU2009231978C1 (en) | 2008-03-31 | 2014-01-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Purine derivatives as A3 adenosine receptor- selective agonists |
| US8916570B2 (en) | 2008-03-31 | 2014-12-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | A3 adenosine receptor agonists and antagonists |
| EP2331542B1 (en) | 2008-08-01 | 2016-07-27 | The United States of America, as Represented by The Secretary, Department of Health and Human Services | A3 adenosine receptor antagonists and partial agonists |
| US9181253B2 (en) | 2008-08-01 | 2015-11-10 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Adenosine receptor agonists, partial agonists, and antagonists |
| KR20120022919A (ko) * | 2009-05-17 | 2012-03-12 | 캔-파이트 바이오파마 리미티드 | 안압의 감소를 위한 ａ3 아데노신 수용체 작동제 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5900407A (en) * | 1997-02-06 | 1999-05-04 | Inspire Pharmaceuticals, Inc. | Method of treating dry eye disease with uridine triphosphates and related compounds |
| JPH10158188A (ja) * | 1996-11-29 | 1998-06-16 | Senju Pharmaceut Co Ltd | 角膜治療用組成物 |
| IL133680A0 (en) * | 1999-09-10 | 2001-04-30 | Can Fite Technologies Ltd | Pharmaceutical compositions comprising an adenosine receptor agonist or antagonist |
| WO2004029025A2 (en) * | 2002-09-27 | 2004-04-08 | Bioenvision, Inc. | Methods and compositions for the treatment of autoimmune disorders using clofarabine |
| JPWO2005121320A1 (ja) * | 2004-06-10 | 2008-04-10 | 協和醗酵工業株式会社 | 幹細胞自己複製促進剤 |
| PL1778239T3 (pl) * | 2004-07-28 | 2014-01-31 | Can Fite Biopharma Ltd | Agoniści receptora adenozynowego A3 do leczenia zaburzeń suchego oka w tym zespołu Sjogrena |
-
2006
- 2006-02-01 BR BRPI0621052-0A patent/BRPI0621052A2/pt not_active IP Right Cessation
- 2006-02-01 WO PCT/IL2006/000130 patent/WO2007086044A1/en not_active Ceased
- 2006-02-01 AU AU2006336834A patent/AU2006336834B2/en not_active Ceased
- 2006-02-01 CA CA2622975A patent/CA2622975C/en not_active Expired - Fee Related
- 2006-02-01 EP EP06701840A patent/EP1976494A1/en not_active Withdrawn
- 2006-02-01 KR KR1020087020322A patent/KR101037095B1/ko not_active Expired - Fee Related
- 2006-02-01 CN CN2006800475697A patent/CN101365430B/zh not_active Expired - Fee Related
- 2006-02-01 JP JP2008551950A patent/JP5185139B2/ja not_active Expired - Fee Related
-
2008
- 2008-05-06 IL IL191271A patent/IL191271A/en not_active IP Right Cessation
-
2012
- 2012-11-12 JP JP2012248668A patent/JP2013032396A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009524647A (ja) | 2009-07-02 |
| JP2013032396A (ja) | 2013-02-14 |
| EP1976494A1 (en) | 2008-10-08 |
| JP5185139B2 (ja) | 2013-04-17 |
| CN101365430A (zh) | 2009-02-11 |
| WO2007086044A1 (en) | 2007-08-02 |
| IL191271A0 (en) | 2009-08-03 |
| CA2622975A1 (en) | 2007-08-02 |
| CA2622975C (en) | 2011-05-03 |
| AU2006336834A1 (en) | 2007-08-02 |
| KR101037095B1 (ko) | 2011-05-26 |
| BRPI0621052A2 (pt) | 2012-07-17 |
| AU2006336834B2 (en) | 2009-12-10 |
| CN101365430B (zh) | 2011-09-21 |
| KR20080090517A (ko) | 2008-10-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| MM9K | Patent not in force due to non-payment of renewal fees |