IL184744A - Parenteral formulation containing effective amount of tmc278 and its use for long-term HIV infection - Google Patents

Parenteral formulation containing effective amount of tmc278 and its use for long-term HIV infection

Info

Publication number
IL184744A
IL184744A IL184744A IL18474407A IL184744A IL 184744 A IL184744 A IL 184744A IL 184744 A IL184744 A IL 184744A IL 18474407 A IL18474407 A IL 18474407A IL 184744 A IL184744 A IL 184744A
Authority
IL
Israel
Prior art keywords
tmc278
hiv
infection
effective amount
long term
Prior art date
Application number
IL184744A
Other languages
English (en)
Hebrew (he)
Other versions
IL184744A0 (en
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of IL184744A0 publication Critical patent/IL184744A0/en
Publication of IL184744A publication Critical patent/IL184744A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL184744A 2005-04-04 2007-07-19 Parenteral formulation containing effective amount of tmc278 and its use for long-term HIV infection IL184744A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05102616 2005-04-04
PCT/EP2006/061303 WO2006106103A2 (en) 2005-04-04 2006-04-04 Prevention of hiv- infection with tmc278

Publications (2)

Publication Number Publication Date
IL184744A0 IL184744A0 (en) 2007-12-03
IL184744A true IL184744A (en) 2015-05-31

Family

ID=34939113

Family Applications (1)

Application Number Title Priority Date Filing Date
IL184744A IL184744A (en) 2005-04-04 2007-07-19 Parenteral formulation containing effective amount of tmc278 and its use for long-term HIV infection

Country Status (29)

Country Link
US (6) US20080194601A1 (pt)
EP (1) EP1881848B1 (pt)
JP (2) JP5632579B2 (pt)
KR (1) KR101360851B1 (pt)
CN (2) CN103860560A (pt)
AP (1) AP2617A (pt)
AR (1) AR053571A1 (pt)
AU (1) AU2006231585B2 (pt)
BR (1) BRPI0607649B8 (pt)
CA (1) CA2602231C (pt)
CY (1) CY1113950T1 (pt)
DK (1) DK1881848T3 (pt)
EA (1) EA011420B1 (pt)
ES (1) ES2402864T3 (pt)
HK (2) HK1117039A1 (pt)
HR (1) HRP20130296T1 (pt)
IL (1) IL184744A (pt)
ME (1) ME01517B (pt)
MX (1) MX2007012277A (pt)
MY (1) MY150091A (pt)
NZ (1) NZ556659A (pt)
PL (1) PL1881848T3 (pt)
PT (1) PT1881848E (pt)
RS (1) RS52724B (pt)
SI (1) SI1881848T1 (pt)
TW (2) TW201414495A (pt)
UA (1) UA90124C2 (pt)
WO (1) WO2006106103A2 (pt)
ZA (1) ZA200708454B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
TW201414495A (zh) * 2005-04-04 2014-04-16 Tibotec Pharm Ltd Hiv-感染之預防
CN103877091A (zh) * 2006-01-20 2014-06-25 泰博特克药品有限公司 用tcm278对hiv感染进行的长期治疗
DK2040671T3 (en) 2006-06-23 2018-05-07 Janssen Sciences Ireland Uc AURAL SUSPENSIONS OF TMC278
CL2008000746A1 (es) 2007-03-14 2008-09-22 Tibotec Pharm Ltd Composicion farmaceutica en solucion que comprende tmc278 y un polimero soluble en agua; proceso de preparacion de dicha composicion; y uso de un polvo que comprende tmc278 para tratar sida.
US20110256206A1 (en) 2008-12-24 2011-10-20 Schachter Deborah M Implantable devices for treating hiv
SG181759A1 (en) * 2009-12-21 2012-07-30 Janssen R & D Ireland Degradable removable implant for the sustained release of an active compound
DE102011082871A1 (de) * 2011-09-16 2013-03-21 Florian, Prof. Dr. Lang Therapeutische und diagnostische Targets für Autoimmunität, inflammatorische Prozesse und/oder immuner Pathogenese und/oder von Erkrankungen, welche auf Autoimmunität, inflammatorische Prozessen und/oder immuner Pathogenese beruhen
JO3387B1 (ar) 2011-12-16 2019-03-13 Glaxosmithkline Llc مشتقات بيتولين
PE20151326A1 (es) 2012-12-14 2015-10-12 Glaxosmithkline Llc Composiciones farmaceuticas que comprenden derivados de betulina
AU2015323321A1 (en) 2014-09-26 2017-04-13 Glaxosmithkline Intellectual Property (No.2) Limited Long acting pharmaceutical compositions
WO2022079739A1 (en) 2020-10-14 2022-04-21 Cipla Limited Fixed dose compositions of cabotegravir and rilpivirine

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06316524A (ja) 1992-09-11 1994-11-15 Naoyuki Inoue 抗エイズウイルス剤
US6258932B1 (en) 1999-08-09 2001-07-10 Tripep Ab Peptides that block viral infectivity and methods of use thereof
HUP0302631A2 (hu) 2000-03-30 2003-11-28 Bristol-Myers Squibb Co. Stavudint tartalmazó elnyújtott hatóanyag-kibocsátású szemcsék
US20040115268A1 (en) * 2000-04-26 2004-06-17 Control Delivery Systems, Inc. Systemic delivery of antiviral agents
MY169670A (en) * 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
JO3429B1 (ar) * 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
WO2004043433A2 (en) 2002-11-08 2004-05-27 Glaxo Group Limited Pharmaceutical antiviral compositions
AU2003282883B2 (en) 2002-11-18 2008-12-04 Polaris Group Methods for inhibiting viral replication in vivo
CL2004000192A1 (es) 2003-02-07 2005-03-18 Janssen Pharmaceutica Nv Uso de compuestos derivados de 2-aminopirimidina para preparar un medicamento para la prevencion de una infeccion por vih relaciones sexuales o un contacto intimo en la pareja.
WO2004073703A1 (en) 2003-02-21 2004-09-02 Tripep Ab Glycinamide derivative for inhibiting hiv replication
TW201414495A (zh) * 2005-04-04 2014-04-16 Tibotec Pharm Ltd Hiv-感染之預防
CN103877091A (zh) * 2006-01-20 2014-06-25 泰博特克药品有限公司 用tcm278对hiv感染进行的长期治疗
DK2040671T3 (en) * 2006-06-23 2018-05-07 Janssen Sciences Ireland Uc AURAL SUSPENSIONS OF TMC278

Also Published As

Publication number Publication date
NZ556659A (en) 2012-03-30
TW201414495A (zh) 2014-04-16
US20110077261A1 (en) 2011-03-31
US20160296519A1 (en) 2016-10-13
CA2602231C (en) 2014-03-25
US20080194601A1 (en) 2008-08-14
BRPI0607649A2 (pt) 2009-09-22
US20220071997A1 (en) 2022-03-10
US10765674B2 (en) 2020-09-08
MX2007012277A (es) 2007-10-17
PT1881848E (pt) 2013-04-15
AU2006231585B2 (en) 2012-02-02
IL184744A0 (en) 2007-12-03
AU2006231585A1 (en) 2006-10-12
CN103860560A (zh) 2014-06-18
WO2006106103A3 (en) 2007-06-07
KR20080009051A (ko) 2008-01-24
ZA200708454B (en) 2009-03-25
BRPI0607649B8 (pt) 2021-05-25
ES2402864T3 (es) 2013-05-09
JP2013079275A (ja) 2013-05-02
CA2602231A1 (en) 2006-10-12
US20160151276A1 (en) 2016-06-02
DK1881848T3 (da) 2013-04-15
BRPI0607649B1 (pt) 2019-08-06
EP1881848A2 (en) 2008-01-30
JP2008534651A (ja) 2008-08-28
EA011420B1 (ru) 2009-02-27
TWI457136B (zh) 2014-10-21
ME01517B (me) 2014-04-20
AR053571A1 (es) 2007-05-09
CN101155599A (zh) 2008-04-02
KR101360851B1 (ko) 2014-02-11
AP2007004178A0 (en) 2007-10-31
HK1198936A1 (en) 2015-06-19
US20200397783A1 (en) 2020-12-24
SI1881848T1 (sl) 2013-05-31
CY1113950T1 (el) 2016-07-27
HRP20130296T1 (hr) 2013-04-30
PL1881848T3 (pl) 2013-06-28
EA200702169A1 (ru) 2008-02-28
JP5632579B2 (ja) 2014-11-26
MY150091A (en) 2013-11-29
HK1117039A1 (en) 2009-01-09
EP1881848B1 (en) 2013-01-16
RS52724B (en) 2013-08-30
WO2006106103A2 (en) 2006-10-12
UA90124C2 (ru) 2010-04-12
TW200709818A (en) 2007-03-16
AP2617A (en) 2013-03-18

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