ZA200708454B - Prevention of HIV-infection with TMC278 - Google Patents

Prevention of HIV-infection with TMC278

Info

Publication number
ZA200708454B
ZA200708454B ZA200708454A ZA200708454A ZA200708454B ZA 200708454 B ZA200708454 B ZA 200708454B ZA 200708454 A ZA200708454 A ZA 200708454A ZA 200708454 A ZA200708454 A ZA 200708454A ZA 200708454 B ZA200708454 B ZA 200708454B
Authority
ZA
South Africa
Prior art keywords
tmc278
hiv
infection
prevention
Prior art date
Application number
ZA200708454A
Other languages
English (en)
Inventor
Baert Lieven Elvire Colette
Lewi Paulus Joannes
Heeres Jan
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of ZA200708454B publication Critical patent/ZA200708454B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA200708454A 2005-04-04 2007-10-03 Prevention of HIV-infection with TMC278 ZA200708454B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05102616 2005-04-04

Publications (1)

Publication Number Publication Date
ZA200708454B true ZA200708454B (en) 2009-03-25

Family

ID=34939113

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200708454A ZA200708454B (en) 2005-04-04 2007-10-03 Prevention of HIV-infection with TMC278

Country Status (29)

Country Link
US (6) US20080194601A1 (pt)
EP (1) EP1881848B1 (pt)
JP (2) JP5632579B2 (pt)
KR (1) KR101360851B1 (pt)
CN (2) CN103860560A (pt)
AP (1) AP2617A (pt)
AR (1) AR053571A1 (pt)
AU (1) AU2006231585B2 (pt)
BR (1) BRPI0607649B8 (pt)
CA (1) CA2602231C (pt)
CY (1) CY1113950T1 (pt)
DK (1) DK1881848T3 (pt)
EA (1) EA011420B1 (pt)
ES (1) ES2402864T3 (pt)
HK (2) HK1117039A1 (pt)
HR (1) HRP20130296T1 (pt)
IL (1) IL184744A (pt)
ME (1) ME01517B (pt)
MX (1) MX2007012277A (pt)
MY (1) MY150091A (pt)
NZ (1) NZ556659A (pt)
PL (1) PL1881848T3 (pt)
PT (1) PT1881848E (pt)
RS (1) RS52724B (pt)
SI (1) SI1881848T1 (pt)
TW (2) TWI457136B (pt)
UA (1) UA90124C2 (pt)
WO (1) WO2006106103A2 (pt)
ZA (1) ZA200708454B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY169670A (en) 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
TWI457136B (zh) * 2005-04-04 2014-10-21 Tibotec Pharm Ltd Ｈｉｖ-感染之預防
WO2007082922A2 (en) 2006-01-20 2007-07-26 Tibotec Pharmaceuticals Ltd. Long term treatment of hiv- infection with tcm278
PL2040671T3 (pl) 2006-06-23 2018-08-31 Janssen Sciences Ireland Uc Wodne zawiesiny TMC278
CL2008000746A1 (es) 2007-03-14 2008-09-22 Tibotec Pharm Ltd Composicion farmaceutica en solucion que comprende tmc278 y un polimero soluble en agua; proceso de preparacion de dicha composicion; y uso de un polvo que comprende tmc278 para tratar sida.
CN102711834B (zh) * 2008-12-24 2015-08-26 爱尔兰詹森科学公司 治疗hiv的可植入装置
CN102740837B (zh) 2009-12-21 2017-06-06 爱尔兰詹森科学公司 用于缓释活性化合物的降解性可摘式植入物
DE102011082871A1 (de) * 2011-09-16 2013-03-21 Florian, Prof. Dr. Lang Therapeutische und diagnostische Targets für Autoimmunität, inflammatorische Prozesse und/oder immuner Pathogenese und/oder von Erkrankungen, welche auf Autoimmunität, inflammatorische Prozessen und/oder immuner Pathogenese beruhen
JO3387B1 (ar) 2011-12-16 2019-03-13 Glaxosmithkline Llc مشتقات بيتولين
BR112015013695A2 (pt) 2012-12-14 2017-07-11 Glaxosmithkline Llc composição farmacêutica, e, métodos para tratamento e para prevenção de uma infecção por hiv
CN106999425A (zh) * 2014-09-26 2017-08-01 葛兰素史克知识产权第二有限公司 长效药物组合物
WO2022079739A1 (en) 2020-10-14 2022-04-21 Cipla Limited Fixed dose compositions of cabotegravir and rilpivirine

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06316524A (ja) 1992-09-11 1994-11-15 Naoyuki Inoue 抗エイズウイルス剤
US6258932B1 (en) 1999-08-09 2001-07-10 Tripep Ab Peptides that block viral infectivity and methods of use thereof
GEP20043285B (en) 2000-03-30 2004-07-26 Bristol Myers Squibb Co Sustained Release Beadlets Containing Stavudine, Method for Their Production, Pharmaceutical Composition Containing the Same and Use Thereof for Treatment Retroviral Infections
US20040115268A1 (en) * 2000-04-26 2004-06-17 Control Delivery Systems, Inc. Systemic delivery of antiviral agents
MY169670A (en) * 2003-09-03 2019-05-08 Tibotec Pharm Ltd Combinations of a pyrimidine containing nnrti with rt inhibitors
JO3429B1 (ar) * 2001-08-13 2019-10-20 Janssen Pharmaceutica Nv مشتقات برميدينات مثبطة فيروس الايدز
WO2004043433A2 (en) 2002-11-08 2004-05-27 Glaxo Group Limited Pharmaceutical antiviral compositions
CN1809378B (zh) 2002-11-18 2010-06-23 德西涅Rx制药公司 体内抑制病毒复制的方法
JP5602333B2 (ja) 2003-02-07 2014-10-08 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Ｈｉｖ感染の予防のためのピリミジン誘導体
AU2004212786A1 (en) 2003-02-21 2004-09-02 Tripep Ab Glycinamide derivative for inhibiting HIV replication
TWI457136B (zh) * 2005-04-04 2014-10-21 Tibotec Pharm Ltd Ｈｉｖ-感染之預防
WO2007082922A2 (en) * 2006-01-20 2007-07-26 Tibotec Pharmaceuticals Ltd. Long term treatment of hiv- infection with tcm278
PL2040671T3 (pl) * 2006-06-23 2018-08-31 Janssen Sciences Ireland Uc Wodne zawiesiny TMC278

Also Published As

Publication number Publication date
EP1881848B1 (en) 2013-01-16
RS52724B (en) 2013-08-30
BRPI0607649A2 (pt) 2009-09-22
IL184744A0 (en) 2007-12-03
PL1881848T3 (pl) 2013-06-28
JP5632579B2 (ja) 2014-11-26
WO2006106103A2 (en) 2006-10-12
AU2006231585A1 (en) 2006-10-12
CY1113950T1 (el) 2016-07-27
AR053571A1 (es) 2007-05-09
CN101155599A (zh) 2008-04-02
US20220071997A1 (en) 2022-03-10
AU2006231585B2 (en) 2012-02-02
AP2007004178A0 (en) 2007-10-31
KR20080009051A (ko) 2008-01-24
HK1198936A1 (en) 2015-06-19
HRP20130296T1 (hr) 2013-04-30
TW201414495A (zh) 2014-04-16
KR101360851B1 (ko) 2014-02-11
ME01517B (me) 2014-04-20
JP2008534651A (ja) 2008-08-28
BRPI0607649B8 (pt) 2021-05-25
DK1881848T3 (da) 2013-04-15
CN103860560A (zh) 2014-06-18
EA200702169A1 (ru) 2008-02-28
EP1881848A2 (en) 2008-01-30
MX2007012277A (es) 2007-10-17
WO2006106103A3 (en) 2007-06-07
CA2602231A1 (en) 2006-10-12
US10765674B2 (en) 2020-09-08
UA90124C2 (ru) 2010-04-12
US20080194601A1 (en) 2008-08-14
BRPI0607649B1 (pt) 2019-08-06
TW200709818A (en) 2007-03-16
MY150091A (en) 2013-11-29
TWI457136B (zh) 2014-10-21
PT1881848E (pt) 2013-04-15
EA011420B1 (ru) 2009-02-27
US20110077261A1 (en) 2011-03-31
JP2013079275A (ja) 2013-05-02
CA2602231C (en) 2014-03-25
NZ556659A (en) 2012-03-30
US20160151276A1 (en) 2016-06-02
HK1117039A1 (en) 2009-01-09
US20160296519A1 (en) 2016-10-13
ES2402864T3 (es) 2013-05-09
SI1881848T1 (sl) 2013-05-31
US20200397783A1 (en) 2020-12-24
AP2617A (en) 2013-03-18
IL184744A (en) 2015-05-31

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