IL170997A - Pharmaceutical composition for treatment and prevention of prostatic hyperplasia and prostatitis from the royal palm (roystonea regia) fruits and the process for preparation thereof - Google Patents
Pharmaceutical composition for treatment and prevention of prostatic hyperplasia and prostatitis from the royal palm (roystonea regia) fruits and the process for preparation thereofInfo
- Publication number
- IL170997A IL170997A IL170997A IL17099705A IL170997A IL 170997 A IL170997 A IL 170997A IL 170997 A IL170997 A IL 170997A IL 17099705 A IL17099705 A IL 17099705A IL 170997 A IL170997 A IL 170997A
- Authority
- IL
- Israel
- Prior art keywords
- fatty acids
- pharmaceutical composition
- acid
- obtention
- fruits
- Prior art date
Links
- 235000006595 Roystonea elata Nutrition 0.000 title claims abstract description 11
- 238000000034 method Methods 0.000 title claims abstract description 9
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 9
- 240000007186 Roystonea regia Species 0.000 title claims abstract description 8
- 235000013399 edible fruits Nutrition 0.000 title claims abstract description 8
- 201000007094 prostatitis Diseases 0.000 title claims abstract description 6
- 230000002265 prevention Effects 0.000 title claims 2
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 title abstract description 4
- 208000004403 Prostatic Hyperplasia Diseases 0.000 title abstract description 4
- 241000899648 Roystonea Species 0.000 title abstract description 3
- 235000008947 Roystonea oleracea Nutrition 0.000 title abstract description 3
- 239000000203 mixture Substances 0.000 claims abstract 11
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract 7
- 201000004384 Alopecia Diseases 0.000 claims abstract 4
- 206010020112 Hirsutism Diseases 0.000 claims abstract 4
- 231100000360 alopecia Toxicity 0.000 claims abstract 4
- 150000002148 esters Chemical class 0.000 claims abstract 4
- 235000021588 free fatty acids Nutrition 0.000 claims abstract 4
- 238000001035 drying Methods 0.000 claims abstract 3
- 238000000605 extraction Methods 0.000 claims abstract 3
- 230000007062 hydrolysis Effects 0.000 claims abstract 3
- 238000006460 hydrolysis reaction Methods 0.000 claims abstract 3
- 239000003960 organic solvent Substances 0.000 claims abstract 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims 8
- 229930195729 fatty acid Natural products 0.000 claims 8
- 239000000194 fatty acid Substances 0.000 claims 8
- 150000004665 fatty acids Chemical class 0.000 claims 8
- IPCSVZSSVZVIGE-UHFFFAOYSA-N palmitic acid group Chemical group C(CCCCCCCCCCCCCCC)(=O)O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 claims 7
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid group Chemical group C(CCCCCCC\C=C/CCCCCCCC)(=O)O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims 5
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 claims 4
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 claims 4
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims 3
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims 3
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims 2
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims 2
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 claims 2
- IMNFDUFMRHMDMM-UHFFFAOYSA-N N-Heptane Chemical compound CCCCCCC IMNFDUFMRHMDMM-UHFFFAOYSA-N 0.000 claims 2
- 239000005642 Oleic acid Substances 0.000 claims 2
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 claims 2
- OFBQJSOFQDEBGM-UHFFFAOYSA-N Pentane Chemical compound CCCCC OFBQJSOFQDEBGM-UHFFFAOYSA-N 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 150000001298 alcohols Chemical class 0.000 claims 2
- 239000002775 capsule Substances 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 229930195733 hydrocarbon Natural products 0.000 claims 2
- 150000002430 hydrocarbons Chemical class 0.000 claims 2
- 150000004679 hydroxides Chemical class 0.000 claims 2
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- SECPZKHBENQXJG-FPLPWBNLSA-N palmitoleic acid Chemical compound CCCCCC\C=C/CCCCCCCC(O)=O SECPZKHBENQXJG-FPLPWBNLSA-N 0.000 claims 2
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims 2
- 238000007127 saponification reaction Methods 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 239000001195 (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid Substances 0.000 claims 1
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical class [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 claims 1
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- 239000005639 Lauric acid Substances 0.000 claims 1
- 235000021314 Palmitic acid Nutrition 0.000 claims 1
- 235000021319 Palmitoleic acid Nutrition 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 235000011114 ammonium hydroxide Nutrition 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 235000011116 calcium hydroxide Nutrition 0.000 claims 1
- SECPZKHBENQXJG-UHFFFAOYSA-N cis-palmitoleic acid Natural products CCCCCCC=CCCCCCCCC(O)=O SECPZKHBENQXJG-UHFFFAOYSA-N 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 239000006210 lotion Substances 0.000 claims 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 claims 1
- TVMXDCGIABBOFY-UHFFFAOYSA-N octane Chemical compound CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 claims 1
- 229960002446 octanoic acid Drugs 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 235000011118 potassium hydroxide Nutrition 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 239000002453 shampoo Substances 0.000 claims 1
- 238000007873 sieving Methods 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 235000011121 sodium hydroxide Nutrition 0.000 claims 1
- 239000000829 suppository Substances 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CU20030062A CU23256A1 (es) | 2003-03-20 | 2003-03-20 | EXTRACTO OBTENIDO A PARTIR DE FRUTOS DE ROYSTONEA REGIA UTILIZADO CONTRA LA HIPERPLASIA PROSTáTICA Y LA PROSTATITIS |
| PCT/CU2004/000004 WO2004082696A1 (es) | 2003-03-20 | 2004-03-15 | Composición farmacéutica y procedimiento para el tratamiento y prevención de la hiperplasia prostática y la prostatitis a partir de los frutos de roystones regia (palma real) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL170997A true IL170997A (en) | 2010-04-15 |
Family
ID=40210497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL170997A IL170997A (en) | 2003-03-20 | 2005-09-20 | Pharmaceutical composition for treatment and prevention of prostatic hyperplasia and prostatitis from the royal palm (roystonea regia) fruits and the process for preparation thereof |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US20060228429A1 (enExample) |
| EP (1) | EP1623740B1 (enExample) |
| JP (1) | JP4693766B2 (enExample) |
| KR (1) | KR100758256B1 (enExample) |
| CN (1) | CN100366246C (enExample) |
| AT (1) | ATE394139T1 (enExample) |
| AU (1) | AU2004222693B2 (enExample) |
| BR (1) | BRPI0409056A (enExample) |
| CA (1) | CA2519410C (enExample) |
| CR (1) | CR8001A (enExample) |
| CU (1) | CU23256A1 (enExample) |
| DE (1) | DE602004013572D1 (enExample) |
| DK (1) | DK1623740T3 (enExample) |
| EC (1) | ECSP056028A (enExample) |
| ES (1) | ES2306999T3 (enExample) |
| IL (1) | IL170997A (enExample) |
| MX (1) | MXPA05009905A (enExample) |
| NO (1) | NO333290B1 (enExample) |
| NZ (1) | NZ542361A (enExample) |
| PT (1) | PT1623740E (enExample) |
| RU (1) | RU2331434C2 (enExample) |
| UA (1) | UA82224C2 (enExample) |
| WO (1) | WO2004082696A1 (enExample) |
| ZA (1) | ZA200507575B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4926395B2 (ja) * | 2004-11-30 | 2012-05-09 | 学校法人 名城大学 | 抗mrsa用組成物 |
| KR100769412B1 (ko) * | 2006-09-13 | 2007-10-22 | 주식회사 벤스랩 | Pr-119 복합생약 추출물을 함유하는 전립선 비대증의예방 및 치료용조성물 |
| WO2010118362A1 (en) | 2009-04-09 | 2010-10-14 | The Regents Of The University Of Colorado, A Body Corporate | Methods and compositions for inducing physiological hypertrophy |
| CU24143B1 (es) * | 2012-06-19 | 2016-01-29 | Cnic Ct Nac Investigaciones | Ingrediente activo para el tratamiento y la prevención de la inflamación y el estrés oxidativo, así como su procedimiento de obtención a partir de los frutos de acrocomina crispa y/o acrocomia aculeata |
| CA2957363C (en) * | 2014-08-12 | 2022-06-21 | Institut de Recherche en Semiochimie et Ethologie Appliquee | Palmitoleic acid for use in inhibiting the attachment of sea lice to fish |
| KR102273967B1 (ko) * | 2014-10-31 | 2021-07-08 | (주)아모레퍼시픽 | 인삼씨유를 함유하여 전립선 비대증을 예방 및 치료하는 조성물 |
| JP2017214342A (ja) * | 2016-06-02 | 2017-12-07 | 日清オイリオグループ株式会社 | 排尿障害の予防用又は改善用組成物 |
| JP6628946B2 (ja) | 2017-12-26 | 2020-01-15 | 大太朗 福岡 | 増毛、頭皮若しくは皮膚の改質、創傷治癒、骨形成促進、または毛髪の改質に用いるための医薬組成物 |
| AU2019212513B2 (en) | 2018-01-26 | 2024-10-31 | Fluidx Medical Technology, Llc | Apparatus and method of using in situ solidifying complex coacervates for vascular occlusion |
| EP4082518A1 (en) | 2021-04-28 | 2022-11-02 | Cnce Innovacion, S.L. | Fatty acid compositions for the treatment and prevention of hair loss and alopecia |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CU21519A1 (en) * | 1983-03-23 | 1987-06-09 | Inst De Quimica Y Biolog Ex | Procedure to facilitate the grinding of roystonea regia fruits |
| TW408127B (en) * | 1993-09-17 | 2000-10-11 | Glaxo Inc | Androstenones |
| CN1184670A (zh) * | 1997-12-23 | 1998-06-17 | 张冰 | 一种治疗前列腺增生、前列腺炎的药物组合物 |
| RU2140265C1 (ru) * | 1998-10-27 | 1999-10-27 | Чернобаев Николай Евгеньевич | Средство для лечения и профилактики доброкачественной гиперплазии простаты (дгп), простатита, импотенции, бесплодия и рака предстательной железы |
-
2003
- 2003-03-20 CU CU20030062A patent/CU23256A1/es unknown
-
2004
- 2004-03-15 PT PT04720576T patent/PT1623740E/pt unknown
- 2004-03-15 CN CNB2004800071887A patent/CN100366246C/zh not_active Expired - Lifetime
- 2004-03-15 RU RU2005130746/15A patent/RU2331434C2/ru not_active Application Discontinuation
- 2004-03-15 AU AU2004222693A patent/AU2004222693B2/en not_active Expired
- 2004-03-15 KR KR1020057017600A patent/KR100758256B1/ko not_active Expired - Lifetime
- 2004-03-15 JP JP2006504216A patent/JP4693766B2/ja not_active Expired - Fee Related
- 2004-03-15 UA UAA200508900A patent/UA82224C2/uk unknown
- 2004-03-15 MX MXPA05009905A patent/MXPA05009905A/es active IP Right Grant
- 2004-03-15 DK DK04720576T patent/DK1623740T3/da active
- 2004-03-15 NZ NZ542361A patent/NZ542361A/xx not_active IP Right Cessation
- 2004-03-15 BR BRPI0409056-0A patent/BRPI0409056A/pt not_active IP Right Cessation
- 2004-03-15 CA CA2519410A patent/CA2519410C/en not_active Expired - Fee Related
- 2004-03-15 ES ES04720576T patent/ES2306999T3/es not_active Expired - Lifetime
- 2004-03-15 EP EP04720576A patent/EP1623740B1/en not_active Expired - Lifetime
- 2004-03-15 AT AT04720576T patent/ATE394139T1/de active
- 2004-03-15 US US10/549,740 patent/US20060228429A1/en not_active Abandoned
- 2004-03-15 DE DE602004013572T patent/DE602004013572D1/de not_active Expired - Lifetime
- 2004-03-15 WO PCT/CU2004/000004 patent/WO2004082696A1/es not_active Ceased
-
2005
- 2005-09-19 ZA ZA200507575A patent/ZA200507575B/xx unknown
- 2005-09-20 EC EC2005006028A patent/ECSP056028A/es unknown
- 2005-09-20 IL IL170997A patent/IL170997A/en not_active IP Right Cessation
- 2005-09-20 CR CR8001A patent/CR8001A/es unknown
- 2005-10-20 NO NO20054847A patent/NO333290B1/no not_active IP Right Cessation
-
2009
- 2009-10-08 US US12/575,584 patent/US20100022649A1/en not_active Abandoned
- 2009-10-08 US US12/575,575 patent/US20100021574A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |