IL166639A0 - Pyridyl substituted heterocycles useful for treating or preventing HCV infection - Google Patents
Pyridyl substituted heterocycles useful for treating or preventing HCV infectionInfo
- Publication number
- IL166639A0 IL166639A0 IL16663905A IL16663905A IL166639A0 IL 166639 A0 IL166639 A0 IL 166639A0 IL 16663905 A IL16663905 A IL 16663905A IL 16663905 A IL16663905 A IL 16663905A IL 166639 A0 IL166639 A0 IL 166639A0
- Authority
- IL
- Israel
- Prior art keywords
- treating
- hcv infection
- pyridyl substituted
- substituted heterocycles
- preventing hcv
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40546702P | 2002-08-23 | 2002-08-23 | |
US41783702P | 2002-10-11 | 2002-10-11 | |
US47137303P | 2003-05-15 | 2003-05-15 | |
US10/646,348 US7157473B2 (en) | 2002-08-23 | 2003-08-22 | Pyridyl substituted heterocycles useful for treating or preventing HCV infection |
PCT/US2003/026478 WO2004018463A2 (en) | 2002-08-23 | 2003-08-22 | Pyridyl substituted heterocycles useful for treating or preventing hcv infection |
Publications (1)
Publication Number | Publication Date |
---|---|
IL166639A0 true IL166639A0 (en) | 2006-01-15 |
Family
ID=31950772
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL16663905A IL166639A0 (en) | 2002-08-23 | 2005-02-01 | Pyridyl substituted heterocycles useful for treating or preventing HCV infection |
Country Status (15)
Country | Link |
---|---|
US (3) | US7157473B2 (ja) |
EP (1) | EP1530569A2 (ja) |
JP (1) | JP2006501312A (ja) |
KR (1) | KR20050033653A (ja) |
AU (1) | AU2003262831A1 (ja) |
BR (1) | BR0313755A (ja) |
CA (1) | CA2494164A1 (ja) |
HR (1) | HRP20050168A2 (ja) |
IL (1) | IL166639A0 (ja) |
MX (1) | MXPA05002082A (ja) |
NO (1) | NO20051404L (ja) |
NZ (1) | NZ537980A (ja) |
PL (1) | PL374536A1 (ja) |
RS (1) | RS20050175A (ja) |
WO (1) | WO2004018463A2 (ja) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY151199A (en) | 2001-11-02 | 2014-04-30 | Rigel Pharmaceuticals Inc | Substituted diphenyl heterocycles useful for treating hcv infection |
PL374536A1 (en) * | 2002-08-23 | 2005-10-31 | Rigel Pharmaceuticals, Inc. | Pyridyl substituted heterocycles useful for treating or preventing hcv infection |
US7115642B2 (en) | 2003-05-02 | 2006-10-03 | Rigel Pharmaceuticals, Inc. | Substituted diphenyl isoxazoles, pyrazoles and oxadiazoles useful for treating HCV infection |
EP1620412A2 (en) * | 2003-05-02 | 2006-02-01 | Rigel Pharmaceuticals, Inc. | Heterocyclic compounds and hydro isomers thereof |
US7220745B2 (en) * | 2003-05-15 | 2007-05-22 | Rigel Pharmaceuticals | Heterocyclic compounds useful to treat HCV |
KR20060084845A (ko) | 2003-07-25 | 2006-07-25 | 이데닉스 (케이만) 리미티드 | C형 간염을 포함하는 플라비비리다에를 치료하기 위한퓨린 뉴클레오시드 유사체 |
WO2005049065A2 (en) * | 2003-11-19 | 2005-06-02 | Rigel Pharmaceuticals, Inc. | Synergistic combinations of dihaloacetamide with interferon or ribavirin for treatment hcv infections |
JP2007514763A (ja) * | 2003-12-19 | 2007-06-07 | ライジェル ファーマシューティカルズ, インコーポレイテッド | C型肝炎ウイルス(hcv)の感染を処置するための組成物および方法 |
US7514434B2 (en) | 2004-02-23 | 2009-04-07 | Rigel Pharmaceuticals, Inc. | Heterocyclic compounds having an oxadiazole moiety and hydro isomers thereof |
JP2007530582A (ja) * | 2004-03-26 | 2007-11-01 | ライジェル ファーマシューティカルズ, インコーポレイテッド | 代謝可能部分を含む複素環抗ウイルス化合物およびその使用 |
JP2008540425A (ja) * | 2005-05-02 | 2008-11-20 | ライジェル ファーマシューティカルズ, インコーポレイテッド | 代謝可能部分を含む複素環式抗ウイルス性化合物およびその使用 |
EP2196153B1 (en) * | 2005-08-10 | 2015-07-01 | C.R.Bard, Inc. | Single-insertion, multiple sample biopsy device |
KR100890862B1 (ko) * | 2005-11-07 | 2009-03-27 | 주식회사 엘지화학 | 유기 발광 소자 및 이의 제조 방법 |
CN103463084A (zh) * | 2008-03-14 | 2013-12-25 | 大塚制药株式会社 | 制剂组合物在制备治疗以mmp-2及/或mmp-9为起因的肺气肿的药物中的应用 |
US8362020B2 (en) * | 2009-12-30 | 2013-01-29 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
BR112017028125A2 (ja) | 2015-06-23 | 2018-08-28 | Kissei Pharmaceutical Co., Ltd. | A pyrazol derivative or its salt permitted pharmacologically |
CN116535399B (zh) * | 2022-01-25 | 2024-02-27 | 中国药科大学 | 3-羟基-5-(异噁唑-5-基)吡啶甲酰甘氨酸类化合物、制法、药物组合物和应用 |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2852503A (en) | 1953-12-31 | 1958-09-16 | American Cyanamid Co | 2, 5-bis (p-aminophenyl) furan azo derivatives |
NL242505A (ja) | 1958-08-20 | |||
US3335149A (en) | 1963-08-21 | 1967-08-08 | Monsanto Co | Thiazole diamines |
FR1459375A (fr) | 1965-10-20 | 1966-04-29 | Westinghouse Electric Corp | Copolymères linéaires oxadiazole-imide |
SU508198A3 (ru) | 1971-07-22 | 1976-03-25 | Группо Лепетит С.П.А. (Фирма) | Способ получени производных 1,2,4-триазола |
DE2137719A1 (de) | 1971-07-28 | 1973-02-08 | Basf Ag | Verfahren zur herstellung von aminobenzonitrilen |
US3964896A (en) | 1971-08-09 | 1976-06-22 | Uniroyal, Inc. | Oxadiazole benzoic acid derivatives as herbicides |
US3853893A (en) | 1973-04-02 | 1974-12-10 | Squibb & Sons Inc | Anthelmintic 5-(pyridyl)-3-(isothiocyanophenyl) oxadiazoles |
DE2721955A1 (de) | 1977-05-14 | 1978-11-23 | Basf Ag | Azofarbstoffe |
DE3623302A1 (de) | 1985-11-09 | 1987-05-14 | Bayer Ag | Nicotinsaeurederivate |
DE4016049A1 (de) | 1990-05-18 | 1991-11-21 | Basf Ag | 3-isoxazolylbenzylester, ihre herstellung und ihre verwendung |
JPH04124178A (ja) | 1990-09-12 | 1992-04-24 | Sds Biotech Kk | 複素環式化合物および該化合物を含有する除草剤 |
DE4124942A1 (de) | 1991-07-27 | 1993-01-28 | Thomae Gmbh Dr K | 5-gliedrige heterocyclen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
DE4137940A1 (de) | 1991-11-18 | 1993-05-19 | Basf Ag | 3-isoxazolylphenylverbindungen, ihre herstellung und ihre verwendung |
JPH07508504A (ja) | 1992-03-06 | 1995-09-21 | リーカ ファーマシュティカルズ エイ/エス | 寄生虫又は細菌による疾患の予防と治療 |
DE4210502A1 (de) | 1992-03-31 | 1993-10-07 | Bayer Ag | Verwendung von 3-aminosubstituierten Isoxazolderivaten zur Bekämpfung von Endoparasiten, neue 3-aminosubstituierte Isoxazolderivate und Verfahren zu ihrer Herstellung |
WO1994017059A1 (en) | 1993-01-29 | 1994-08-04 | Nippon Soda Co., Ltd. | Heterocyclic derivative |
DE4408084A1 (de) | 1994-03-10 | 1995-09-14 | Hoechst Ag | 3,5-Disubstituierte und 3,4,5-trisubstituierte 2-Isoxazoline und Isoxazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
US5962685A (en) | 1994-08-02 | 1999-10-05 | Nippon Soda Co., Ltd. | Oxazole derivatives, process for producing the same, and herbicide |
CN1151147C (zh) * | 1995-02-02 | 2004-05-26 | 史密丝克莱恩比彻姆有限公司 | 作为5-ht受体拮抗剂的吲哚衍生物 |
DE19643037A1 (de) | 1996-10-18 | 1998-04-23 | Boehringer Ingelheim Kg | Neue Oxadiazole, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel |
US20020035156A1 (en) | 1997-04-18 | 2002-03-21 | Barbara Roniker | Combination therapy in the prevention of cardiovascular disorders |
AU745797B2 (en) | 1997-04-18 | 2002-03-28 | G.D. Searle & Co. | Method of using cyclooxygenase-2 inhibitors in the prevention of cardiovascular disorders |
WO1999004390A1 (fr) | 1997-07-17 | 1999-01-28 | Sony Corporation | Support d'enregistrement magnetique et dispositif d'enregistrement/de reproduction magnetique le comprenant |
EP1025857A4 (en) | 1997-10-22 | 2003-11-12 | Eisai Co Ltd | RETINOIC ACID AGONISTS, PREVENTIVE AND THERAPEUTIC AGENTS FOR NEPHRITES |
DE19860802A1 (de) | 1998-12-30 | 2000-10-26 | Virgene Pharmaceuticals Ag | Herstellung eines Mittels gegen Hepatitis B-, HI-, Paramyxo und Orthomyxo-Viren |
DE19904389A1 (de) | 1999-02-04 | 2000-08-10 | Bayer Ag | Verwendung von substituierten Isoxazolcarbonsäuren und Derivate und neue Stoffe |
EP1180518B1 (en) | 1999-04-23 | 2007-01-17 | Takeda Pharmaceutical Company Limited | 5-pyridyl-1,3-azole compounds, process for producing the same and use thereof |
GB2351081A (en) | 1999-06-18 | 2000-12-20 | Lilly Forschung Gmbh | Pharmaceutically active imidazoline compounds and analogues thereof |
DE10032874A1 (de) | 2000-07-06 | 2002-01-17 | Bayer Ag | Arzneimittelkombinationen gegen virale Erkrankungen |
US7495018B2 (en) * | 2000-03-30 | 2009-02-24 | Takeda Pharmaceutical Company Limited | Substituted 1,3-thiazole compounds, their production and use |
US6608058B2 (en) * | 2000-04-17 | 2003-08-19 | Dong Wha Pharm. Ind. Co., Ltd. | 6-methylnicotinamide derivatives as antiviral agents |
US6579880B2 (en) | 2000-06-06 | 2003-06-17 | Ortho-Mcneil Pharmaceutical, Inc. | Isoxazoles and oxadiazoles as anti-inflammatory inhibitors of IL-8 |
GB0017676D0 (en) * | 2000-07-19 | 2000-09-06 | Angeletti P Ist Richerche Bio | Inhibitors of viral polymerase |
US20020077491A1 (en) | 2000-09-05 | 2002-06-20 | Shipps Gerald W. | Methods for forming combinatorial libraries combining amide bond formation with epoxide opening |
EP1348706B1 (en) * | 2000-12-08 | 2009-08-19 | Takeda Pharmaceutical Company Limited | Substituted thiazole derivatives bearing 3-pyridyl groups, process for preparing the same and use thereof |
US20030199521A1 (en) | 2001-01-13 | 2003-10-23 | Dykstra Christine C. | Compounds, methods and compositions useful for the treatment of bovine viral diarrhea virus (BVDV) infection and hepatitis C virus (HCV) infection |
DE10148598A1 (de) * | 2001-04-19 | 2002-10-24 | Bayer Ag | Neue Arylsulfonamide als antivirale Mittel |
CN1516695A (zh) * | 2001-04-19 | 2004-07-28 | 用作抗病毒剂的芳基磺酰胺类化合物 | |
WO2003029210A2 (en) * | 2001-10-04 | 2003-04-10 | Merck & Co. Inc. | Heteroaryl substituted tetrazole modulators of metabotropic glutamate receptor-5 |
MY151199A (en) | 2001-11-02 | 2014-04-30 | Rigel Pharmaceuticals Inc | Substituted diphenyl heterocycles useful for treating hcv infection |
PL374536A1 (en) | 2002-08-23 | 2005-10-31 | Rigel Pharmaceuticals, Inc. | Pyridyl substituted heterocycles useful for treating or preventing hcv infection |
US7220745B2 (en) | 2003-05-15 | 2007-05-22 | Rigel Pharmaceuticals | Heterocyclic compounds useful to treat HCV |
-
2003
- 2003-08-22 PL PL03374536A patent/PL374536A1/xx not_active Application Discontinuation
- 2003-08-22 WO PCT/US2003/026478 patent/WO2004018463A2/en active Application Filing
- 2003-08-22 MX MXPA05002082A patent/MXPA05002082A/es unknown
- 2003-08-22 NZ NZ537980A patent/NZ537980A/en not_active IP Right Cessation
- 2003-08-22 KR KR1020057003019A patent/KR20050033653A/ko not_active Application Discontinuation
- 2003-08-22 RS YUP-2005/0175A patent/RS20050175A/sr unknown
- 2003-08-22 BR BR0313755-4A patent/BR0313755A/pt not_active IP Right Cessation
- 2003-08-22 US US10/646,348 patent/US7157473B2/en active Active
- 2003-08-22 EP EP03793349A patent/EP1530569A2/en not_active Withdrawn
- 2003-08-22 JP JP2005501778A patent/JP2006501312A/ja active Pending
- 2003-08-22 CA CA002494164A patent/CA2494164A1/en not_active Abandoned
- 2003-08-22 AU AU2003262831A patent/AU2003262831A1/en not_active Abandoned
-
2005
- 2005-02-01 IL IL16663905A patent/IL166639A0/xx unknown
- 2005-02-22 HR HR20050168A patent/HRP20050168A2/hr not_active Application Discontinuation
- 2005-03-17 NO NO20051404A patent/NO20051404L/no not_active Application Discontinuation
-
2006
- 2006-11-21 US US11/561,991 patent/US7332602B2/en not_active Expired - Lifetime
-
2007
- 2007-12-20 US US11/960,990 patent/US7714137B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
MXPA05002082A (es) | 2005-06-08 |
US7157473B2 (en) | 2007-01-02 |
NO20051404L (no) | 2005-05-10 |
US20080171871A1 (en) | 2008-07-17 |
WO2004018463A2 (en) | 2004-03-04 |
BR0313755A (pt) | 2005-06-21 |
WO2004018463A3 (en) | 2004-05-06 |
JP2006501312A (ja) | 2006-01-12 |
PL374536A1 (en) | 2005-10-31 |
US7332602B2 (en) | 2008-02-19 |
US20070155966A1 (en) | 2007-07-05 |
US7714137B2 (en) | 2010-05-11 |
NZ537980A (en) | 2007-08-31 |
US20040127497A1 (en) | 2004-07-01 |
KR20050033653A (ko) | 2005-04-12 |
EP1530569A2 (en) | 2005-05-18 |
HRP20050168A2 (en) | 2005-10-31 |
AU2003262831A1 (en) | 2004-03-11 |
RS20050175A (en) | 2007-09-21 |
CA2494164A1 (en) | 2004-03-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL166639A0 (en) | Pyridyl substituted heterocycles useful for treating or preventing HCV infection | |
EP1451162A4 (en) | SUBSTITUTED DIPHENYL HETEROCYCLES USEFUL FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTION | |
HK1080073A1 (en) | Alkyne-aryl phosphodiesterase-4 inhibitors | |
IL209352A0 (en) | 4-tetrazolyl-4phenylpiperidine derivatives for treating pain | |
HK1091815A1 (en) | [1,8]naphthyridin-2-ones and related compounds for the treatment of schizophrenia | |
IL161401A0 (en) | Organic waste treatment | |
IL156595A0 (en) | Therapeutic heterocyclic compounds | |
IL164621A0 (en) | Pestidical heterocycles | |
IL160208A0 (en) | Amidine derivatives for treating amyloidosis | |
HK1074005A1 (en) | Compositions and methods for treating or preventing pneumococcal infection | |
IL164352A0 (en) | Methods for treating tweak-related conditions | |
GB0211257D0 (en) | Novel heterocycles | |
IL159540A0 (en) | Heterocyclic compounds as selective bacterial dhfr inhibitors and the uses thereof | |
AU2003249181A8 (en) | Methods for treating or preventing ischemic injury | |
GB0123437D0 (en) | Heterocyclic compounds | |
AU2003259202A8 (en) | Compositions and methods for treating and preventing infection | |
FI20022150A0 (fi) | Menetelmä kuonan käsittelemiseksi | |
AU2003237088A8 (en) | Compounds, compositions and methods for treating or preventing viral infections and associated diseases | |
ZA200501298B (en) | Pyridyl substituted heterocycles useful for treating or preventing HCV infection | |
AU2003258176A8 (en) | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases | |
AU2003254129A8 (en) | Method and composition for treating and preventing hepatitis b infection and symptoms thereof | |
AU2003256678A8 (en) | Method and composition for treating and preventing hepatitis c infection | |
PL1867644T3 (pl) | Związki heteroarylo-tetrahydropiperydylowe przydatne w leczeniu lub zapobieganiu bólu | |
EP1589994A4 (en) | PREPARATION AND METHOD FOR PREVENTING OR TREATING VIRAL INFECTION | |
FR2833294B1 (fr) | Fermeture perfectionnee |