IL166412A0 - Novel use of benzothiazole derivatives - Google Patents
Novel use of benzothiazole derivativesInfo
- Publication number
- IL166412A0 IL166412A0 IL16641205A IL16641205A IL166412A0 IL 166412 A0 IL166412 A0 IL 166412A0 IL 16641205 A IL16641205 A IL 16641205A IL 16641205 A IL16641205 A IL 16641205A IL 166412 A0 IL166412 A0 IL 166412A0
- Authority
- IL
- Israel
- Prior art keywords
- sub
- novel use
- benzothiazole derivatives
- formula
- disclosed
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
- C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0202429A SE0202429D0 (sv) | 2002-08-14 | 2002-08-14 | Novel Compounds |
| PCT/SE2003/001271 WO2004016600A1 (en) | 2002-08-14 | 2003-08-13 | Novel use of benzothiazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL166412A0 true IL166412A0 (en) | 2006-01-15 |
Family
ID=20288724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16641205A IL166412A0 (en) | 2002-08-14 | 2005-01-20 | Novel use of benzothiazole derivatives |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20060106015A1 (xx) |
| EP (1) | EP1539723B1 (xx) |
| JP (1) | JP2006504672A (xx) |
| KR (1) | KR20060002728A (xx) |
| CN (1) | CN1675189A (xx) |
| AT (1) | ATE327225T1 (xx) |
| AU (1) | AU2003248587A1 (xx) |
| BR (1) | BR0313407A (xx) |
| CA (1) | CA2495492A1 (xx) |
| DE (1) | DE60305514D1 (xx) |
| IL (1) | IL166412A0 (xx) |
| MX (1) | MXPA05001585A (xx) |
| NO (1) | NO20051263L (xx) |
| SE (1) | SE0202429D0 (xx) |
| WO (1) | WO2004016600A1 (xx) |
| ZA (1) | ZA200501098B (xx) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1781628A2 (en) * | 2004-08-26 | 2007-05-09 | Wyeth a Corporation of the State of Delaware | Prodrug substituted benzoxazoles as estrogenic agents |
| RU2007134414A (ru) | 2005-02-17 | 2009-03-27 | Амр Текнолоджи, Инк. (Us) | Бензоксазолкарбоксамиды для лечения индуцированной химиотерапией тошноты и рвоты (cini) и синдрома раздраженного кишечника с преобладанием диареи (ibs-d) |
| DK1910384T3 (da) | 2005-08-04 | 2012-12-17 | Sirtris Pharmaceuticals Inc | Imidazo [2,1-b] thiazol-derivater som sirtuinmodulerende forbindelser |
| US8088928B2 (en) | 2005-08-04 | 2012-01-03 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
| US8093401B2 (en) | 2005-08-04 | 2012-01-10 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
| US7855289B2 (en) | 2005-08-04 | 2010-12-21 | Sirtris Pharmaceuticals, Inc. | Sirtuin modulating compounds |
| ATE514663T1 (de) * | 2007-05-07 | 2011-07-15 | Siemens Ag | Keramisches pulver, keramische schicht und schichtsystem mit pyrochlorphase und oxiden |
| CL2008001822A1 (es) | 2007-06-20 | 2009-03-13 | Sirtris Pharmaceuticals Inc | Compuestos derivados de tiazolo[5,4-b]piridina; composicion farmaceutica que comprende a dichos compuestos; y uso del compuesto en el tratamiento de la resistencia a la insulina, sindrome metabolico, diabetes, entre otras. |
| AU2008315746A1 (en) * | 2007-10-25 | 2009-04-30 | Astrazeneca Ab | Pyridine and pyrazine derivatives useful in the treatment of cell proliferative disorders |
| EP2376502B1 (en) | 2008-12-19 | 2015-06-17 | GlaxoSmithKline LLC | Thiazolopyridine sirtuin modulating compounds |
| WO2013153539A1 (en) | 2012-04-13 | 2013-10-17 | Glenmark Pharmaceuticals S.A. | Tricyclic compounds as tec kinase inhibitors |
| EP3060218A4 (en) | 2013-10-25 | 2017-07-19 | Pharmacyclics LLC | Methods of treating and preventing graft versus host disease |
| US10238650B2 (en) | 2015-03-06 | 2019-03-26 | Beyondspring Pharmaceuticals, Inc. | Method of treating cancer associated with a RAS mutation |
| US20170209462A1 (en) | 2015-08-31 | 2017-07-27 | Pharmacyclics Llc | Btk inhibitor combinations for treating multiple myeloma |
| SG11201806583XA (en) | 2016-02-08 | 2018-09-27 | Beyondspring Pharmaceuticals Inc | Compositions containing tucaresol or its analogs |
| EP3534938A2 (en) | 2016-11-03 | 2019-09-11 | Juno Therapeutics, Inc. | Combination therapy of a t cell therapy and a btk inhibitor |
| WO2018111049A1 (ko) * | 2016-12-15 | 2018-06-21 | 한국생명공학연구원 | 피리딘계 화합물을 유효성분으로 함유하는 dyrk 관련 질환의 예방 또는 치료용 약학적 조성물 |
| KR102279347B1 (ko) | 2016-12-15 | 2021-07-21 | 한국생명공학연구원 | 피리딘계 화합물을 유효성분으로 함유하는 dyrk 관련 질환의 예방 또는 치료용 약학적 조성물 |
| CN110431135A (zh) | 2017-01-06 | 2019-11-08 | 大连万春布林医药有限公司 | 微管蛋白结合化合物及其治疗用途 |
| US11786523B2 (en) | 2018-01-24 | 2023-10-17 | Beyondspring Pharmaceuticals, Inc. | Composition and method for reducing thrombocytopenia |
| SI3762368T1 (sl) | 2018-03-08 | 2022-06-30 | Incyte Corporation | Aminopirazin diolne spojine kot zaviralci PI3K-y |
| CA3098497A1 (en) | 2018-05-03 | 2019-11-07 | Juno Therapeutics, Inc. | Combination therapy of a chimeric antigen receptor (car) t cell therapy and a kinase inhibitor |
| US11046658B2 (en) | 2018-07-02 | 2021-06-29 | Incyte Corporation | Aminopyrazine derivatives as PI3K-γ inhibitors |
| CN112778155B (zh) * | 2019-11-11 | 2023-08-11 | 大连万春布林医药有限公司 | 妥卡雷琐衍生物及其用途 |
| WO2023220655A1 (en) | 2022-05-11 | 2023-11-16 | Celgene Corporation | Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE581862A (xx) * | 1958-08-22 | |||
| DE2145178C3 (de) * | 1970-09-11 | 1975-12-11 | Tokyo Tanabe Co., Ltd., Tokio | 2-Phenyl-5-oder -6-benzothiazolylessigsäure-Verblndungen |
| JPS4932855B1 (xx) * | 1971-08-03 | 1974-09-03 | ||
| DD150059A1 (de) * | 1980-04-07 | 1981-08-12 | Horst Hartmann | Verfahren zur herstellung von hydroxyarylazolen |
| JPS62221679A (ja) * | 1986-03-19 | 1987-09-29 | Santen Pharmaceut Co Ltd | ベンゾチアゾリン誘導体 |
| DE4030511A1 (de) * | 1990-09-27 | 1992-04-02 | Basf Ag | Hochtemperaturbestaendige, benzthiazolhaltige polyarylether |
| US5296486A (en) * | 1991-09-24 | 1994-03-22 | Boehringer Ingelheim Pharmaceuticals, Inc. | Leukotriene biosynthesis inhibitors |
| HUP0102101A3 (en) * | 1997-11-10 | 2002-11-28 | Bristol Myers Squibb Co | Protein tyrosine kinase inhibitor benzothiazole derivatives and pharmaceutical compositions containing them |
| AU2001251083A1 (en) * | 2000-03-31 | 2001-10-15 | Ortho-Mcneil Pharmaceutical, Inc. | Method for using 2-aryloxyalkylaminobenzoxazoles and 2-aryloxyalkylaminobenzothiazoles as h3 antagonists |
| WO2002051821A1 (en) * | 2000-12-22 | 2002-07-04 | Astrazeneca Ab | Therapeutic compounds |
| JP2002306916A (ja) * | 2001-01-26 | 2002-10-22 | Toray Ind Inc | エアフィルタユニット |
-
2002
- 2002-08-14 SE SE0202429A patent/SE0202429D0/xx unknown
-
2003
- 2003-08-13 AU AU2003248587A patent/AU2003248587A1/en not_active Abandoned
- 2003-08-13 KR KR1020057002297A patent/KR20060002728A/ko not_active Application Discontinuation
- 2003-08-13 US US10/524,124 patent/US20060106015A1/en not_active Abandoned
- 2003-08-13 DE DE60305514T patent/DE60305514D1/de not_active Expired - Lifetime
- 2003-08-13 MX MXPA05001585A patent/MXPA05001585A/es unknown
- 2003-08-13 EP EP03788208A patent/EP1539723B1/en not_active Expired - Lifetime
- 2003-08-13 AT AT03788208T patent/ATE327225T1/de not_active IP Right Cessation
- 2003-08-13 WO PCT/SE2003/001271 patent/WO2004016600A1/en active IP Right Grant
- 2003-08-13 CN CNA038191393A patent/CN1675189A/zh active Pending
- 2003-08-13 JP JP2004528996A patent/JP2006504672A/ja active Pending
- 2003-08-13 CA CA002495492A patent/CA2495492A1/en not_active Abandoned
- 2003-08-13 BR BR0313407-5A patent/BR0313407A/pt not_active Application Discontinuation
-
2005
- 2005-01-20 IL IL16641205A patent/IL166412A0/xx unknown
- 2005-02-07 ZA ZA200501098A patent/ZA200501098B/xx unknown
- 2005-03-11 NO NO20051263A patent/NO20051263L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1539723A1 (en) | 2005-06-15 |
| ATE327225T1 (de) | 2006-06-15 |
| ZA200501098B (en) | 2006-12-27 |
| AU2003248587A1 (en) | 2004-03-03 |
| BR0313407A (pt) | 2005-07-05 |
| JP2006504672A (ja) | 2006-02-09 |
| CN1675189A (zh) | 2005-09-28 |
| DE60305514D1 (de) | 2006-06-29 |
| EP1539723B1 (en) | 2006-05-24 |
| CA2495492A1 (en) | 2004-02-26 |
| SE0202429D0 (sv) | 2002-08-14 |
| WO2004016600A1 (en) | 2004-02-26 |
| US20060106015A1 (en) | 2006-05-18 |
| NO20051263L (no) | 2005-05-12 |
| KR20060002728A (ko) | 2006-01-09 |
| MXPA05001585A (es) | 2005-04-25 |
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