IL165330A0 - Aromatic sulfones and their medical use - Google Patents

Aromatic sulfones and their medical use

Info

Publication number
IL165330A0
IL165330A0 IL16533003A IL16533003A IL165330A0 IL 165330 A0 IL165330 A0 IL 165330A0 IL 16533003 A IL16533003 A IL 16533003A IL 16533003 A IL16533003 A IL 16533003A IL 165330 A0 IL165330 A0 IL 165330A0
Authority
IL
Israel
Prior art keywords
medical use
aromatic sulfones
sulfones
aromatic
medical
Prior art date
Application number
IL16533003A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0212401A external-priority patent/GB0212401D0/en
Priority claimed from GB0230053A external-priority patent/GB0230053D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IL165330A0 publication Critical patent/IL165330A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL16533003A 2002-05-29 2003-05-28 Aromatic sulfones and their medical use IL165330A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0212401A GB0212401D0 (en) 2002-05-29 2002-05-29 Compounds
GB0230053A GB0230053D0 (en) 2002-12-23 2002-12-23 Compounds
PCT/EP2003/005727 WO2003099786A2 (en) 2002-05-29 2003-05-28 Aromatic sulfones and their medical use

Publications (1)

Publication Number Publication Date
IL165330A0 true IL165330A0 (en) 2006-01-15

Family

ID=29585827

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16533003A IL165330A0 (en) 2002-05-29 2003-05-28 Aromatic sulfones and their medical use

Country Status (26)

Country Link
US (2) US7504392B2 (ru)
EP (1) EP1511727B1 (ru)
JP (1) JP4268126B2 (ru)
KR (1) KR20050013196A (ru)
AR (1) AR040126A1 (ru)
AT (1) ATE354566T1 (ru)
AU (1) AU2003232846B9 (ru)
BR (1) BR0311315A (ru)
CA (1) CA2486962A1 (ru)
CY (1) CY1107053T1 (ru)
DE (1) DE60311986T2 (ru)
DK (1) DK1511727T3 (ru)
ES (1) ES2279965T3 (ru)
HK (1) HK1075050A1 (ru)
IL (1) IL165330A0 (ru)
IS (1) IS2482B (ru)
MX (1) MXPA04011945A (ru)
MY (1) MY133587A (ru)
NO (1) NO330118B1 (ru)
NZ (1) NZ536694A (ru)
PL (1) PL374081A1 (ru)
PT (1) PT1511727E (ru)
RU (1) RU2327690C2 (ru)
SI (1) SI1511727T1 (ru)
TW (1) TWI281914B (ru)
WO (1) WO2003099786A2 (ru)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY133587A (en) 2002-05-29 2007-11-30 Glaxo Group Ltd Aromatic sulfones and their medical use
AU2003243637A1 (en) * 2002-06-19 2004-01-06 Schering Corporation Cannabinoid receptor agonists
GB0319235D0 (en) * 2003-08-15 2003-09-17 Glaxo Group Ltd Novel compounds
GB0327738D0 (en) * 2003-11-28 2003-12-31 Glaxo Group Ltd Novel compound
GB0327740D0 (en) * 2003-11-28 2003-12-31 Glaxo Group Ltd Novel compounds
GB0327741D0 (en) * 2003-11-28 2003-12-31 Glaxo Group Ltd Novel compounds
GB0327737D0 (en) * 2003-11-28 2003-12-31 Glaxo Group Ltd Novel compounds
GB0505437D0 (en) * 2005-03-17 2005-04-20 Merck Sharp & Dohme Therapeutic agents
GB0505725D0 (en) * 2005-03-19 2005-04-27 Merck Sharp & Dohme Therapeutic agents
JP5114381B2 (ja) * 2005-03-31 2013-01-09 アミリン・ファーマシューティカルズ，インコーポレイテッド 精神疾患および障害治療用アミリンおよびアミリンアゴニスト
GB0510599D0 (en) * 2005-05-24 2005-06-29 Glaxo Group Ltd Novel compounds
GB0603087D0 (en) * 2006-02-15 2006-03-29 Glaxo Group Ltd Novel use
US20070293475A1 (en) * 2006-06-20 2007-12-20 Alcon Manufacturing Ltd. Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma
CA2742863C (en) * 2008-11-06 2017-05-09 Ventirx Pharmaceuticals, Inc. Methods of synthesis of benzazepine derivatives
US20180228811A1 (en) * 2014-12-12 2018-08-16 The Schepens Eye Research Institute, Inc. Gdnf induction for the treatment of retinal disorders
US11124497B1 (en) 2020-04-17 2021-09-21 Pardes Biosciences, Inc. Inhibitors of cysteine proteases and methods of use thereof
US11174231B1 (en) 2020-06-09 2021-11-16 Pardes Biosciences, Inc. Inhibitors of cysteine proteases and methods of use thereof
US11351149B2 (en) 2020-09-03 2022-06-07 Pfizer Inc. Nitrile-containing antiviral compounds

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DE3869446D1 (de) * 1987-03-10 1992-04-30 Lion Corp Desodorierungsmittel.
EP0285287A3 (en) 1987-03-23 1990-08-16 Smithkline Beecham Corporation 3-benzazepine compounds for use in treating gastrointestinal motility disorders
GB8717374D0 (en) 1987-07-22 1987-08-26 Smith Kline French Lab Pharmaceutically active compounds
US5032604A (en) 1989-12-08 1991-07-16 Merck & Co., Inc. Class III antiarrhythmic agents
GB9127041D0 (en) 1991-12-20 1992-02-19 Fujisawa Pharmaceutical Co New use
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WO1995023150A1 (fr) 1994-02-25 1995-08-31 Banyu Pharmaceutical Co., Ltd. Derive de carbapendem
US5684195A (en) * 1994-07-14 1997-11-04 G. D. Searle & Co. Method of preparing sulfmonamides from sulfones
EP0828754B1 (en) 1995-05-29 2005-02-02 Pfizer Inc. Dipeptides which promote release of growth hormone
DE19548785A1 (de) 1995-12-27 1997-07-03 Basf Ag Saure Polyazofarbstoffe
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AU4204697A (en) 1996-08-14 1998-03-06 Smithkline Beecham Plc Tetrahydroisoquinoline derivatives and their pharmaceutical use
DE19638484A1 (de) 1996-09-20 1998-03-26 Basf Ag Hetaroylderivate
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GB9708805D0 (en) 1997-05-01 1997-06-25 Smithkline Beecham Plc Compounds
EP0937723A1 (de) 1998-02-18 1999-08-25 Roche Diagnostics GmbH Neue Sulfonamide, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
GB9804734D0 (en) * 1998-03-05 1998-04-29 Pfizer Ltd Compounds
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BR0115328A (pt) 2000-11-14 2004-04-06 Smithkline Beecham Plc Derivados de tetraidro benzazepina úteis como moduladores dos receptores d3 de dopamina (agentes anti-psicóticos
AU2002222853A1 (en) 2000-12-07 2002-06-18 Astrazeneca Ab Therapeutic compounds
GB0111186D0 (en) 2001-05-08 2001-06-27 Smithkline Beecham Plc Novel compounds
WO2003062205A1 (en) 2001-12-21 2003-07-31 Smithkline Beecham P.L.C. 7-sulfonyl-3-benzazepine derivatives as modulators of the dopamine receptor and their use for the treatment of cns disorders
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EP1495004A2 (en) 2002-02-13 2005-01-12 Glaxo Group Limited Benzenesulfonamide derivatives and their use as dopamine d3 and d2 receptor ligands
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GB0212399D0 (en) 2002-05-29 2002-07-10 Glaxo Group Ltd Compounds
MY133587A (en) 2002-05-29 2007-11-30 Glaxo Group Ltd Aromatic sulfones and their medical use

Also Published As

Publication number Publication date
IS2482B (is) 2008-12-15
CA2486962A1 (en) 2003-12-04
EP1511727A2 (en) 2005-03-09
US7504392B2 (en) 2009-03-17
KR20050013196A (ko) 2005-02-03
EP1511727B1 (en) 2007-02-21
AU2003232846B9 (en) 2007-04-19
CY1107053T1 (el) 2012-10-24
TWI281914B (en) 2007-06-01
DE60311986D1 (de) 2007-04-05
NZ536694A (en) 2006-11-30
NO20045659L (no) 2004-12-27
US20050261279A1 (en) 2005-11-24
PT1511727E (pt) 2007-05-31
AR040126A1 (es) 2005-03-16
JP4268126B2 (ja) 2009-05-27
PL374081A1 (en) 2005-09-19
IS7577A (is) 2004-12-01
AU2003232846A1 (en) 2003-12-12
RU2004138588A (ru) 2005-06-27
ATE354566T1 (de) 2007-03-15
NO330118B1 (no) 2011-02-21
WO2003099786A3 (en) 2004-09-02
HK1075050A1 (en) 2005-12-02
MXPA04011945A (es) 2005-03-31
DE60311986T2 (de) 2007-10-31
SI1511727T1 (sl) 2007-06-30
ES2279965T3 (es) 2007-09-01
TW200406381A (en) 2004-05-01
WO2003099786A2 (en) 2003-12-04
JP2005531579A (ja) 2005-10-20
BR0311315A (pt) 2005-03-01
DK1511727T3 (da) 2007-06-11
AU2003232846B2 (en) 2007-02-22
RU2327690C2 (ru) 2008-06-27
MY133587A (en) 2007-11-30
US20080269197A1 (en) 2008-10-30

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