IL164311A0 - Compounds useful in preparing coamptothecin derivatives - Google Patents
Compounds useful in preparing coamptothecin derivativesInfo
- Publication number
- IL164311A0 IL164311A0 IL16431104A IL16431104A IL164311A0 IL 164311 A0 IL164311 A0 IL 164311A0 IL 16431104 A IL16431104 A IL 16431104A IL 16431104 A IL16431104 A IL 16431104A IL 164311 A0 IL164311 A0 IL 164311A0
- Authority
- IL
- Israel
- Prior art keywords
- coamptothecin
- derivatives
- preparing
- compounds useful
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
- C07D211/58—Nitrogen atoms attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US37372702P | 2002-04-17 | 2002-04-17 | |
| PCT/US2003/011551 WO2003089413A1 (en) | 2002-04-17 | 2003-04-16 | Pharmacia corporation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL164311A0 true IL164311A0 (en) | 2005-12-18 |
Family
ID=29251068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16431104A IL164311A0 (en) | 2002-04-17 | 2004-09-27 | Compounds useful in preparing coamptothecin derivatives |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6723729B2 (xx) |
| EP (1) | EP1501799A1 (xx) |
| JP (1) | JP3839813B2 (xx) |
| KR (1) | KR20050009293A (xx) |
| CN (1) | CN1646491A (xx) |
| AU (1) | AU2003224973A1 (xx) |
| BR (1) | BR0309284A (xx) |
| CA (1) | CA2482712A1 (xx) |
| IL (1) | IL164311A0 (xx) |
| MX (1) | MXPA04009426A (xx) |
| PL (1) | PL371681A1 (xx) |
| RS (1) | RS91304A (xx) |
| RU (1) | RU2287527C2 (xx) |
| WO (1) | WO2003089413A1 (xx) |
| ZA (1) | ZA200407821B (xx) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050197355A1 (en) * | 2004-03-02 | 2005-09-08 | Henegar Kevin E. | Compounds useful in preparing camptothecin derivatives |
| WO2006016203A1 (en) * | 2004-08-09 | 2006-02-16 | Shilpa Medicare Limited | An improved process for the preparation of irinotecan hydrochloride trihydrate |
| JP5133705B2 (ja) * | 2005-02-07 | 2013-01-30 | フェルミオン オサケ ユキチュア | ７−エチル−１０−ヒドロキシカンプトテシンの製造方法 |
| JP5133703B2 (ja) * | 2005-02-08 | 2013-01-30 | フェルミオン オサケ ユキチュア | ［１，４’］ビピペリジニル−１’−カルボニルクロリドまたはその塩酸塩の製造方法 |
| EP1928883B1 (en) * | 2005-02-08 | 2013-10-30 | Fermion Oy | Process for the preparation of irinotecan hydrochloride |
| TWI375678B (en) * | 2005-06-09 | 2012-11-01 | Yakult Honsha Kk | A method of preparation of a tricyclic ketone |
| WO2008035377A2 (en) * | 2006-09-18 | 2008-03-27 | Shilpa Medicare Ltd. | Novel intermediates for the preparation of camptothecin analogues |
| US8546573B2 (en) * | 2009-11-18 | 2013-10-01 | Cadila Healthcare Limited | Process for the preparation of 7-ethyl-10-[4-(1-piperidino)-1-piperdino] carbonyloxy-camptothecin hydrochloride trihydrate |
| WO2012032531A1 (en) * | 2010-09-06 | 2012-03-15 | Avra Laboratories Pvt. Ltd. | Process for the manufacture of irinotecan hydrochloride by total synthesis |
| EP2881396A1 (en) * | 2013-12-03 | 2015-06-10 | Synbias Pharma AG | Method for the synthesis of irinotecan |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL117684A (en) | 1995-04-07 | 2002-02-10 | Pharmacia & Upjohn Inc | Intermediates and Process for Production of History of Kempotocin (CPT-11) and Related Compounds |
-
2003
- 2003-04-16 JP JP2003586134A patent/JP3839813B2/ja not_active Expired - Fee Related
- 2003-04-16 WO PCT/US2003/011551 patent/WO2003089413A1/en not_active Application Discontinuation
- 2003-04-16 RU RU2004130493/04A patent/RU2287527C2/ru not_active IP Right Cessation
- 2003-04-16 US US10/414,852 patent/US6723729B2/en not_active Expired - Fee Related
- 2003-04-16 KR KR10-2004-7016524A patent/KR20050009293A/ko not_active Application Discontinuation
- 2003-04-16 BR BR0309284-4A patent/BR0309284A/pt not_active IP Right Cessation
- 2003-04-16 CN CNA038083353A patent/CN1646491A/zh active Pending
- 2003-04-16 PL PL03371681A patent/PL371681A1/xx not_active Application Discontinuation
- 2003-04-16 CA CA002482712A patent/CA2482712A1/en not_active Abandoned
- 2003-04-16 MX MXPA04009426A patent/MXPA04009426A/es unknown
- 2003-04-16 RS YUP-913/04A patent/RS91304A/sr unknown
- 2003-04-16 EP EP03721671A patent/EP1501799A1/en not_active Withdrawn
- 2003-04-16 AU AU2003224973A patent/AU2003224973A1/en not_active Abandoned
-
2004
- 2004-09-27 IL IL16431104A patent/IL164311A0/xx unknown
- 2004-09-28 ZA ZA200407821A patent/ZA200407821B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RS91304A (xx) | 2007-02-05 |
| MXPA04009426A (es) | 2005-01-25 |
| PL371681A1 (en) | 2005-06-27 |
| ZA200407821B (en) | 2005-06-29 |
| AU2003224973A1 (en) | 2003-11-03 |
| US20040048832A1 (en) | 2004-03-11 |
| CA2482712A1 (en) | 2003-10-30 |
| RU2004130493A (ru) | 2005-04-20 |
| WO2003089413A1 (en) | 2003-10-30 |
| JP2005523324A (ja) | 2005-08-04 |
| JP3839813B2 (ja) | 2006-11-01 |
| KR20050009293A (ko) | 2005-01-24 |
| CN1646491A (zh) | 2005-07-27 |
| BR0309284A (pt) | 2005-02-22 |
| RU2287527C2 (ru) | 2006-11-20 |
| EP1501799A1 (en) | 2005-02-02 |
| US6723729B2 (en) | 2004-04-20 |
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