IL163529A0 - Novel spinosyn-producing polyketidesynthases - Google Patents

Novel spinosyn-producing polyketidesynthases

Info

Publication number
IL163529A0
IL163529A0 IL16352903A IL16352903A IL163529A0 IL 163529 A0 IL163529 A0 IL 163529A0 IL 16352903 A IL16352903 A IL 16352903A IL 16352903 A IL16352903 A IL 16352903A IL 163529 A0 IL163529 A0 IL 163529A0
Authority
IL
Israel
Prior art keywords
polyketidesynthases
producing
novel spinosyn
spinosyn
novel
Prior art date
Application number
IL16352903A
Other languages
English (en)
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Publication of IL163529A0 publication Critical patent/IL163529A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/22—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom rings with more than six members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Pest Control & Pesticides (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Catching Or Destruction (AREA)
IL16352903A 2002-02-19 2003-02-19 Novel spinosyn-producing polyketidesynthases IL163529A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35807502P 2002-02-19 2002-02-19
PCT/US2003/004998 WO2003070908A2 (en) 2002-02-19 2003-02-19 Novel spinosyn-producing polyketide synthases

Publications (1)

Publication Number Publication Date
IL163529A0 true IL163529A0 (en) 2005-12-18

Family

ID=27757699

Family Applications (3)

Application Number Title Priority Date Filing Date
IL16352903A IL163529A0 (en) 2002-02-19 2003-02-19 Novel spinosyn-producing polyketidesynthases
IL16352904A IL163529A (en) 2002-02-19 2004-08-12 Spinosyn-producing polyketide synthases
IL200471A IL200471A (en) 2002-02-19 2009-08-18 Polynucleide syntheses produce spinosine

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL16352904A IL163529A (en) 2002-02-19 2004-08-12 Spinosyn-producing polyketide synthases
IL200471A IL200471A (en) 2002-02-19 2009-08-18 Polynucleide syntheses produce spinosine

Country Status (11)

Country Link
US (5) US20030225006A1 (da)
EP (1) EP1492404B1 (da)
JP (1) JP4765032B2 (da)
KR (1) KR101016561B1 (da)
CN (1) CN1633237B (da)
AU (2) AU2003217591B2 (da)
DK (1) DK1492404T3 (da)
ES (1) ES2375714T3 (da)
IL (3) IL163529A0 (da)
MX (1) MXPA04008071A (da)
WO (1) WO2003070908A2 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL163529A0 (en) 2002-02-19 2005-12-18 Dow Agrosciences Llc Novel spinosyn-producing polyketidesynthases
GB0327720D0 (en) 2003-11-28 2003-12-31 Biotica Tech Ltd Erythromycins and process for their preparation
GB0417852D0 (en) 2004-08-11 2004-09-15 Biotica Tech Ltd Production of polyketides and other natural products
WO2007144786A2 (en) * 2006-05-26 2007-12-21 Entarco Sa The vapor-phase application of spinosyn for the control of pests, and formulations and products utilizing the same
CN102202506B (zh) * 2008-09-22 2015-07-29 克里斯廷·克里蒂考 刺糖多孢菌素防污组合物、其使用方法、以及受到保护而免于附着污损生物的制品
AU2010213749B2 (en) * 2009-02-11 2015-01-22 Dow Agrosciences Llc Pesticidal compositions
JP5619868B2 (ja) * 2009-04-03 2014-11-05 ダウ アグロサイエンシーズエルエルシー 水性エマルションを解乳化および分離するための解乳化組成物、系および方法
US8268975B2 (en) 2009-04-03 2012-09-18 Dow Agrosciences Llc Demulsification compositions, systems and methods for demulsifying and separating aqueous emulsions
CA2764526A1 (en) 2009-06-24 2010-12-29 Christine Kritikou The use of spinosyns and spinosyn compositions against diseases caused by protozoans, viral infections and cancer
EP2272963A1 (en) 2009-07-09 2011-01-12 LEK Pharmaceuticals d.d. Process for Preparation of Tacrolimus
RU2580015C2 (ru) 2010-05-11 2016-04-10 ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи Штаммы spnk
CN101942425B (zh) * 2010-08-24 2012-06-20 北京农学院 与苯亚甲基丙酮合成相关的酶及其编码基因与应用
EP2654757A1 (en) 2010-12-22 2013-10-30 Entarco SA The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents
US9404107B2 (en) 2011-05-03 2016-08-02 Dow Agrosciences Llc Integration of genes into the chromosome of Saccharopolyspora spinosa
DK2520653T3 (da) 2011-05-03 2017-07-03 Dow Agrosciences Llc Integration af gener i kromosomet af saccharopolyspora spinosa
US9631195B2 (en) 2011-12-28 2017-04-25 Dow Agrosciences Llc Identification and characterization of the spinactin biosysnthesis gene cluster from spinosyn producing saccharopolyspora spinosa
JP6641366B2 (ja) * 2014-11-14 2020-02-05 浙江海正薬業股▲ふん▼有限公司Ｚｈｅｊｉａｎｇ Ｈｉｓｕｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌ ＣＯ．，ＬＴＤ． スピノサド異種発現株およびその構築方法ならびに使用
JP2018532708A (ja) 2015-09-03 2018-11-08 アグリメティス，エルエルシー 殺虫剤としてのスピノシン誘導体
WO2018226893A2 (en) 2017-06-06 2018-12-13 Zymergen Inc. A high-throughput (htp) genomic engineering platform for improving saccharopolyspora spinosa
AU2021256845A1 (en) * 2020-04-14 2022-11-24 Eidgenössische Technische Hochschule Zürich Cell classifier circuits and methods of use thereof
CN116240191B (zh) * 2023-03-23 2026-03-27 上海交通大学 一种泰乐菌素聚酮合酶酰基转移酶突变体及其应用
CN116334021B (zh) * 2023-03-30 2026-02-03 上海交通大学 一种多杀菌素酰基转移酶突变体及其应用

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CA1117005A (en) 1978-03-07 1982-01-26 Patrick G. Feakins Animal ear-tags, their manufacture and their use
OA09249A (fr) 1988-12-19 1992-06-30 Lilly Co Eli Composés de macrolides.
US5362634A (en) * 1989-10-30 1994-11-08 Dowelanco Process for producing A83543 compounds
US5824513A (en) * 1991-01-17 1998-10-20 Abbott Laboratories Recombinant DNA method for producing erythromycin analogs
WO1993013663A1 (en) 1992-01-17 1993-07-22 Abbott Laboratories Method of directing biosynthesis of specific polyketides
CN1073483A (zh) * 1991-11-08 1993-06-23 道伊兰科公司 一种发酵杀虫剂化合物及其制备方法
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US5591606A (en) * 1992-11-06 1997-01-07 Dowelanco Process for the production of A83543 compounds with Saccharopolyspora spinosa
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CA2197524A1 (en) * 1996-02-22 1997-08-22 Bradley Stuart Dehoff Polyketide synthase genes
US6001981A (en) 1996-06-13 1999-12-14 Dow Agrosciences Llc Synthetic modification of Spinosyn compounds
ES2244001T3 (es) * 1996-07-05 2005-12-01 Biotica Technology Limited Eritromicinas y procedimiento para su preparacion.
JP3441899B2 (ja) 1996-11-01 2003-09-02 理化学研究所 完全長ｃＤＮＡライブラリーの作成方法
CO5060464A1 (es) 1997-12-23 2001-07-30 Novartis Ag Metodos para controlar plagas con una composicion plaguicida que comprende un compuesto macrolido
US6143526A (en) * 1998-03-09 2000-11-07 Baltz; Richard H. Biosynthetic genes for spinosyn insecticide production
DE19823397B4 (de) 1998-05-26 2011-07-28 Bayer CropScience AG, 40789 Verwendung von Spinosynen zum Einsatz als Bodeninsektizide
GB9814006D0 (en) * 1998-06-29 1998-08-26 Biotica Tech Ltd Polyketides and their synthesis
ID29130A (id) 1998-07-02 2001-08-02 Lilly Co Eli Formulasi pengendali kutu pada manusia
GB9814622D0 (en) * 1998-07-06 1998-09-02 Biotica Tech Ltd Polyketides,their preparation,and materials for use therein
MXPA01003376A (es) * 1998-10-02 2002-11-07 Kosan Biosciences Inc Enzimas policetido sintetasa y construcciones de acido desoxirribonucleico recombinante para las mismas.
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JP2000245457A (ja) * 1999-02-24 2000-09-12 Kitasato Inst:The エバーメクチンアグリコン合成酵素遺伝子
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US7285653B1 (en) * 1999-08-27 2007-10-23 Bayer Aktiengesellschaft Nucleic acids which code for the enzyme activities of the spinosyn biosynthesis
ATE280176T1 (de) * 1999-09-13 2004-11-15 Dow Agrosciences Llc Pestizide makrolide
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TWI275592B (en) * 2001-03-21 2007-03-11 Dow Agrosciences Llc Synthetic derivatives of 21-butenyl and related spinosyns
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IL163529A0 (en) * 2002-02-19 2005-12-18 Dow Agrosciences Llc Novel spinosyn-producing polyketidesynthases
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Also Published As

Publication number Publication date
CN1633237B (zh) 2010-05-26
EP1492404B1 (en) 2011-12-28
AU2003217591B2 (en) 2009-02-26
CN1633237A (zh) 2005-06-29
US7626010B2 (en) 2009-12-01
US20030225006A1 (en) 2003-12-04
JP2005520500A (ja) 2005-07-14
IL200471A (en) 2015-09-24
WO2003070908A3 (en) 2004-10-28
US8624009B2 (en) 2014-01-07
US20060040877A1 (en) 2006-02-23
ES2375714T3 (es) 2012-03-05
WO2003070908A2 (en) 2003-08-28
JP4765032B2 (ja) 2011-09-07
MXPA04008071A (es) 2004-11-26
US20100068785A1 (en) 2010-03-18
EP1492404A2 (en) 2005-01-05
KR20040085201A (ko) 2004-10-07
IL163529A (en) 2011-11-30
EP1492404A4 (en) 2010-03-17
US20110178036A1 (en) 2011-07-21
US9137992B2 (en) 2015-09-22
AU2003217591A1 (en) 2003-09-09
AU2009200685B2 (en) 2012-01-12
US20140080777A1 (en) 2014-03-20
IL200471A0 (en) 2011-07-31
KR101016561B1 (ko) 2011-02-22
AU2009200685A1 (en) 2009-03-12
DK1492404T3 (da) 2012-04-23

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