IL162292A0 - 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials - Google Patents

6-O-acyl ketolide derivatives of erythromycine useful as antibacterials

Info

Publication number
IL162292A0
IL162292A0 IL16229202A IL16229202A IL162292A0 IL 162292 A0 IL162292 A0 IL 162292A0 IL 16229202 A IL16229202 A IL 16229202A IL 16229202 A IL16229202 A IL 16229202A IL 162292 A0 IL162292 A0 IL 162292A0
Authority
IL
Israel
Prior art keywords
erythromycine
antibacterials
acyl
useful
ketolide derivatives
Prior art date
Application number
IL16229202A
Other languages
English (en)
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of IL162292A0 publication Critical patent/IL162292A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
IL16229202A 2001-12-05 2002-11-21 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials IL162292A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33856601P 2001-12-05 2001-12-05
US39251302P 2002-06-28 2002-06-28
PCT/US2002/037433 WO2003050132A1 (en) 2001-12-05 2002-11-21 6-o-acyl ketolide derivatives of erythromycine useful as antibacterials

Publications (1)

Publication Number Publication Date
IL162292A0 true IL162292A0 (en) 2005-11-20

Family

ID=26991254

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16229202A IL162292A0 (en) 2001-12-05 2002-11-21 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials

Country Status (16)

Country Link
US (1) US6825170B2 (zh)
EP (1) EP1453847A1 (zh)
JP (1) JP2005511752A (zh)
CN (1) CN1585775A (zh)
AR (1) AR038005A1 (zh)
AU (1) AU2002346475A1 (zh)
BR (1) BR0214748A (zh)
CA (1) CA2469304A1 (zh)
HU (1) HUP0500018A3 (zh)
IL (1) IL162292A0 (zh)
MX (1) MXPA04005424A (zh)
NZ (1) NZ533282A (zh)
PL (1) PL370714A1 (zh)
RU (1) RU2004117082A (zh)
TW (1) TW200418497A (zh)
WO (1) WO2003050132A1 (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003102010A1 (en) * 2002-05-31 2003-12-11 Janssen Pharmaceutica N.V. 3-descladinosyl-6-o-carbamoyl and 6-o-carbonoyl macrolide antibacterial agents
WO2004078771A1 (ja) * 2003-03-07 2004-09-16 Taisho Pharmaceutical Co., Ltd. ２－フルオロ－６－ｏ－置換ケトライド誘導体
WO2005121160A2 (en) * 2004-04-26 2005-12-22 Johnson & Johnson Pharmaceutical Research & Development 11, 12 cyclic thiocarbamate macrolide antibacterial agents
BR122015028990B8 (pt) * 2007-04-03 2017-12-26 Du Pont composto, composições fungicidas e método de controle de doenças das plantas
DE102009004061A1 (de) 2009-01-08 2010-07-15 Merck Patent Gmbh Pyridazinonderivate
US9173396B2 (en) 2010-10-22 2015-11-03 Bayer Intellectual Property Gmbh Heterocyclic compounds as pesticides
CN103958525A (zh) 2011-11-30 2014-07-30 埃科特莱茵药品有限公司 3,7-二取代八氢-2H-吡啶并[4,3-e][1,3]噁嗪-2-酮抗生素
CA3130061C (en) 2013-04-04 2024-05-28 President And Fellows Of Harvard College Macrolides and methods of their preparation and use
AR097617A1 (es) 2013-09-13 2016-04-06 Actelion Pharmaceuticals Ltd Derivados antibacterianos del 2h-indazol
CA2963815A1 (en) * 2014-10-08 2016-04-14 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
CA2980315A1 (en) 2015-03-25 2016-09-29 President And Fellows Of Harvard College Macrolides with modified desosamine sugars and uses thereof
CN110028447B (zh) * 2019-05-17 2022-10-14 济南大学 一种2-一氟甲基喹啉衍生物的制备方法

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8521402D0 (en) 1985-08-28 1985-10-02 Beecham Group Plc Chemical compounds
IL99995A (en) 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US5559256A (en) 1992-07-20 1996-09-24 E. R. Squibb & Sons, Inc. Aminediol protease inhibitors
US5780473A (en) 1995-02-06 1998-07-14 Bristol-Myers Squibb Company Substituted biphenyl sulfonamide endothelin antagonists
WO1997017356A1 (en) 1995-11-08 1997-05-15 Abbott Laboratories Tricyclic erythromycin derivatives
PL327626A1 (en) 1995-12-29 1998-12-21 Smithkline Beecham Corp Antagonists of vitronectin receptor
US6451973B1 (en) 1996-07-17 2002-09-17 Novatis Ag Anilinopeptide derivatives
UA51730C2 (uk) 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
ATE296832T1 (de) 1996-09-04 2005-06-15 Abbott Lab 6-o-substituierte ketoliden mit antibakteriellen wirkung
UA56197C2 (uk) 1996-11-08 2003-05-15 Зенека Лімітед Гетероциклічні похідні
UA59384C2 (uk) 1996-12-20 2003-09-15 Пфайзер, Інк. Похідні сульфонамідів та амідів як агоністи простагландину, фармацевтична композиція та способи лікування на їх основі
US6034069A (en) * 1997-09-30 2000-03-07 Abbott Laboratories 3-'N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity
AR015986A1 (es) 1997-10-29 2001-05-30 Abbott Lab Derivados de eritromicina puenteados en 6,11, composiciones farmaceuticas que los contienen, su uso para la manufactura de un medicamento y procedimientospara su preparacion
CO4990960A1 (es) 1997-10-29 2000-12-26 Abbott Lab Derivados de cetolidos 2-halo-6-o sustituidos
AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
US5992683A (en) 1998-08-31 1999-11-30 Kimberly-Clark Worldwide, Inc. Clip lift for sheet dispensing system
US6395710B1 (en) 1999-04-16 2002-05-28 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
MXPA01010521A (es) 1999-04-16 2003-08-19 Johnson & Johnson Antibacteriales de cetolidos.
US6355620B1 (en) 1999-05-14 2002-03-12 Abbott Laboratories C-2 modified erythromycin derivatives
WO2000071557A1 (en) 1999-05-24 2000-11-30 Pfizer Products Inc. 13-methyl-erythromycin derivatives
PT1181300E (pt) 1999-06-07 2004-02-27 Abbott Lab Derivados 6-o-carbamato de cetolido
MXPA02005192A (es) 1999-12-02 2003-01-28 Abbott Lab Derivados de cetolido 6-o-alquil-2-nor-2-sustituido.
EP1114826A3 (en) 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1146051A3 (en) 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
UY26964A1 (es) 2000-10-16 2002-06-20 Abbott Lab Derivados de eritromicina 6-0-sustituidos con mayor tolerancia gastrointestinal
US6472372B1 (en) * 2000-12-06 2002-10-29 Ortho-Mcneil Pharmaceuticals, Inc. 6-O-Carbamoyl ketolide antibacterials
EP1499326A1 (en) 2002-04-25 2005-01-26 Abbott Laboratories Oxolide antibacterials
CA2484095A1 (en) 2002-04-30 2003-11-13 Abbott Laboratories Tricyclic macrolide antibacterial compounds

Also Published As

Publication number Publication date
TW200418497A (en) 2004-10-01
US6825170B2 (en) 2004-11-30
HUP0500018A3 (en) 2009-09-28
BR0214748A (pt) 2004-11-23
CN1585775A (zh) 2005-02-23
HUP0500018A2 (en) 2006-09-28
EP1453847A1 (en) 2004-09-08
US20030220272A1 (en) 2003-11-27
JP2005511752A (ja) 2005-04-28
CA2469304A1 (en) 2003-06-19
MXPA04005424A (es) 2005-06-20
RU2004117082A (ru) 2005-04-10
NZ533282A (en) 2006-09-29
PL370714A1 (en) 2005-05-30
AU2002346475A1 (en) 2003-06-23
WO2003050132A1 (en) 2003-06-19
AR038005A1 (es) 2004-12-22

Similar Documents

Publication Publication Date Title
IL156329A0 (en) 6-o-carbamoyl ketolide derivatives of erythromycin useful as antibacterials
HK1208446A1 (zh) 的衍生物
HK1066218A1 (en) Qunazoline derivatives as antitumor agents
AU2002243969A1 (en) Rod to rod connector
TWI318880B (en) Azalide antibiotic compositions
IL145976A0 (en) Ketolide antibacterials
IL161996A0 (en) Directly compressible formulations of azithromycin
GB0127349D0 (en) Macrolides
IL155504A0 (en) Ketolide antibacterials
IL162292A0 (en) 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials
IL158236A0 (en) Pharmaceutical compositions containing azithromycin and derivatives thereof
AU2002330717A1 (en) Monosaccharide derivatives
AU2003293635A1 (en) 4'' - modified erythromycin derivatives
PL369674A1 (en) Pyrazole derivatives as psychopharmaceuticals
IL161560A0 (en) Anthelmintic compositions containing milbemycin derivatives
GB0129988D0 (en) Imidazolidineacetic acid derivatives
ZA200507475B (en) Derivatives of azithromycin
AU2001214115A1 (en) Process for the preparation of anhydrous azithromycin
AU2002317415A1 (en) Azalide antibiotic compositions
ZA200405252B (en) 6-O-Acyl ketolide derivatives of erythromycine useful as antibacterials.
HUP0402108A3 (en) Macrolides containing pharmaceutical compositions
SI1638984T1 (sl) Monosaharidni derivati avermektina B1
AU2002346601A1 (en) Novel 11-o-substituted ketolide derivatives
AU2002232183A1 (en) 12- and 13-modified novel 16-membered macrolide derivatives
AU2003253701A1 (en) 11-c-substituted derivatives of clarithromycin