IL161580A0 - Pyrrole, pyrazole, imidazole, triazole and tetrazole derivatives and their use - Google Patents

Pyrrole, pyrazole, imidazole, triazole and tetrazole derivatives and their use

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Publication number
IL161580A0
IL161580A0 IL16158002A IL16158002A IL161580A0 IL 161580 A0 IL161580 A0 IL 161580A0 IL 16158002 A IL16158002 A IL 16158002A IL 16158002 A IL16158002 A IL 16158002A IL 161580 A0 IL161580 A0 IL 161580A0
Authority
IL
Israel
Prior art keywords
pyrazole
pyrrole
triazole
imidazole
tetrazole derivatives
Prior art date
Application number
IL16158002A
Other languages
English (en)
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of IL161580A0 publication Critical patent/IL161580A0/xx

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    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4164—1,3-Diazoles
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IL16158002A 2001-10-23 2002-10-23 Pyrrole, pyrazole, imidazole, triazole and tetrazole derivatives and their use IL161580A0 (en)

Applications Claiming Priority (2)

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US33604001P 2001-10-23 2001-10-23
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US8546404B2 (en) 2005-12-13 2013-10-01 Merck Sharp & Dohme Compounds that are ERK inhibitors
CN101415674A (zh) 2006-02-16 2009-04-22 先灵公司 作为erk抑制剂的吡咯烷衍生物
CN102015693B (zh) 2008-02-21 2014-10-29 默沙东公司 作为erk抑制剂的化合物
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WO2010051933A2 (fr) 2008-11-10 2010-05-14 Bayer Schering Pharma Aktiengesellschaft Sulfonamido phénoxybenzamides substitués
EP2370568B1 (fr) 2008-12-10 2017-07-19 Dana-Farber Cancer Institute, Inc. Mutations de mek conférant une résistance aux inhibiteurs de mek
JP2013508318A (ja) 2009-10-21 2013-03-07 バイエル・ファルマ・アクチェンゲゼルシャフト 置換されたベンゾスルホンアミド誘導体
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WO2015041533A1 (fr) 2013-09-20 2015-03-26 Stichting Het Nederlands Kanker Instituut Association de rock et de la voie mapk
WO2015041534A1 (fr) 2013-09-20 2015-03-26 Stichting Het Nederlands Kanker Instituut P90rsk en combinaison avec raf/erk/mek
WO2015156674A2 (fr) 2014-04-10 2015-10-15 Stichting Het Nederlands Kanker Instituut Méthode de traitement du cancer
WO2015178770A1 (fr) 2014-05-19 2015-11-26 Stichting Het Nederlands Kanker Instituut Compositions pour le traitement du cancer
US10864179B2 (en) 2015-10-01 2020-12-15 Stichting Het Nederlands Kanker Instituut-Antoni van Leeuwenhoek Ziekenhuis Histone deacetylase inhibitors for the use in the treatment of drug resistant melanoma
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CN110845703A (zh) * 2019-10-28 2020-02-28 上海瀚岱化学有限公司 一种水性环氧树脂及其制备方法
CN110903735A (zh) * 2019-11-11 2020-03-24 上海瀚岱化学有限公司 一种水性环氧涂料及其制备方法与应用
WO2021221953A1 (fr) 2020-04-28 2021-11-04 The Regents Of The University Of Michigan Inhibiteurs pyridine de la glucosylcéramide synthase et procédés thérapeutiques les utilisant
CN112794989A (zh) * 2020-12-18 2021-05-14 江西瀚泰新材料科技有限公司 一种增韧阻燃水性环氧树脂及其制备方法
CN112759742A (zh) * 2020-12-18 2021-05-07 江西瀚泰新材料科技有限公司 一种增韧型水性环氧树脂及其制备方法
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CA2463101A1 (fr) 2003-05-01
ES2393186T3 (es) 2012-12-19
JP2005508972A (ja) 2005-04-07
US7253199B2 (en) 2007-08-07
WO2003035626A2 (fr) 2003-05-01
JP4602667B2 (ja) 2010-12-22
AU2008202731A1 (en) 2008-07-17
WO2003035626A3 (fr) 2003-11-06
EP1438295B1 (fr) 2012-08-15
US20070293555A1 (en) 2007-12-20
AU2002359291C1 (en) 2008-11-20
US20050054706A1 (en) 2005-03-10
US7541375B2 (en) 2009-06-02
EP2332922A1 (fr) 2011-06-15
AU2002359291B2 (en) 2008-04-03
EP1438295A2 (fr) 2004-07-21

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