IL161320A0 - Quinoline derivatives, synthesis method, and medicines containing said derivatives - Google Patents
Quinoline derivatives, synthesis method, and medicines containing said derivativesInfo
- Publication number
- IL161320A0 IL161320A0 IL16132002A IL16132002A IL161320A0 IL 161320 A0 IL161320 A0 IL 161320A0 IL 16132002 A IL16132002 A IL 16132002A IL 16132002 A IL16132002 A IL 16132002A IL 161320 A0 IL161320 A0 IL 161320A0
- Authority
- IL
- Israel
- Prior art keywords
- sub
- derivatives
- synthesis method
- coor
- cooh
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
- 238000001308 synthesis method Methods 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- -1 -COOR Chemical group 0.000 abstract 1
- 102000012330 Integrases Human genes 0.000 abstract 1
- 108010061833 Integrases Proteins 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 241001430294 unidentified retrovirus Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0113209A FR2830863B1 (fr) | 2001-10-12 | 2001-10-12 | Derives de quinoleine, procede de synthese, et medicaments renfermant ces derives |
| PCT/FR2002/003512 WO2003031413A1 (fr) | 2001-10-12 | 2002-10-14 | Derives de quinoleine, procede de synthese, et medicaments renfermant ces derives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL161320A0 true IL161320A0 (en) | 2004-09-27 |
Family
ID=8868255
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL16132002A IL161320A0 (en) | 2001-10-12 | 2002-10-14 | Quinoline derivatives, synthesis method, and medicines containing said derivatives |
| IL161320A IL161320A (en) | 2001-10-12 | 2004-04-07 | Quinoline derivatives, a method for their synthesis, pharmaceutical compositiions comprising the same and uses thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL161320A IL161320A (en) | 2001-10-12 | 2004-04-07 | Quinoline derivatives, a method for their synthesis, pharmaceutical compositiions comprising the same and uses thereof |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7064133B2 (enExample) |
| EP (1) | EP1461319B1 (enExample) |
| JP (1) | JP2005508350A (enExample) |
| AT (1) | ATE430134T1 (enExample) |
| DE (1) | DE60232186D1 (enExample) |
| DK (1) | DK1461319T3 (enExample) |
| ES (1) | ES2326115T3 (enExample) |
| FR (1) | FR2830863B1 (enExample) |
| IL (2) | IL161320A0 (enExample) |
| WO (1) | WO2003031413A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2830863B1 (fr) * | 2001-10-12 | 2004-01-30 | Bioalliance Pharma | Derives de quinoleine, procede de synthese, et medicaments renfermant ces derives |
| FR2839646B1 (fr) * | 2002-05-17 | 2008-04-11 | Bioalliance Pharma | Utilisation de derives de quinoleine a effet anti-integrase et ses applications |
| US7132432B2 (en) * | 2003-06-05 | 2006-11-07 | Bristol-Myers Squibb Company | Hydantoin derivatives as inhibitors of tumor necrosis factor-alpha converting enzyme (TACE) |
| TW200510425A (en) | 2003-08-13 | 2005-03-16 | Japan Tobacco Inc | Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor |
| ATE433974T1 (de) | 2003-09-19 | 2009-07-15 | Gilead Sciences Inc | Azachinolinolphosphonatverbindungen als integraseinhibitoren |
| JP2008542352A (ja) * | 2005-06-01 | 2008-11-27 | ビオアリアンス ファルマ | キノリン化合物及び他のｈｉｖ感染治療薬を含む相乗作用のコンビネーション |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2761687B1 (fr) * | 1997-04-08 | 2000-09-15 | Centre Nat Rech Scient | Derives de quinoleines, possedant notamment des proprietes antivirales, leurs preparations et leurs applications biologiques |
| FR2830863B1 (fr) * | 2001-10-12 | 2004-01-30 | Bioalliance Pharma | Derives de quinoleine, procede de synthese, et medicaments renfermant ces derives |
-
2001
- 2001-10-12 FR FR0113209A patent/FR2830863B1/fr not_active Expired - Fee Related
-
2002
- 2002-10-14 DK DK02795314T patent/DK1461319T3/da active
- 2002-10-14 ES ES02795314T patent/ES2326115T3/es not_active Expired - Lifetime
- 2002-10-14 WO PCT/FR2002/003512 patent/WO2003031413A1/fr not_active Ceased
- 2002-10-14 US US10/492,088 patent/US7064133B2/en not_active Expired - Fee Related
- 2002-10-14 JP JP2003534397A patent/JP2005508350A/ja active Pending
- 2002-10-14 IL IL16132002A patent/IL161320A0/xx unknown
- 2002-10-14 EP EP02795314A patent/EP1461319B1/fr not_active Expired - Lifetime
- 2002-10-14 DE DE60232186T patent/DE60232186D1/de not_active Expired - Lifetime
- 2002-10-14 AT AT02795314T patent/ATE430134T1/de not_active IP Right Cessation
-
2004
- 2004-04-07 IL IL161320A patent/IL161320A/en not_active IP Right Cessation
-
2006
- 2006-03-01 US US11/364,329 patent/US20060148849A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20060148849A1 (en) | 2006-07-06 |
| FR2830863B1 (fr) | 2004-01-30 |
| EP1461319B1 (fr) | 2009-04-29 |
| WO2003031413A1 (fr) | 2003-04-17 |
| FR2830863A1 (fr) | 2003-04-18 |
| JP2005508350A (ja) | 2005-03-31 |
| DK1461319T3 (da) | 2009-08-03 |
| US7064133B2 (en) | 2006-06-20 |
| ATE430134T1 (de) | 2009-05-15 |
| US20040259911A1 (en) | 2004-12-23 |
| ES2326115T3 (es) | 2009-10-01 |
| IL161320A (en) | 2009-09-01 |
| DE60232186D1 (de) | 2009-06-10 |
| EP1461319A1 (fr) | 2004-09-29 |
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