DE60232186D1 - Chinolinderivate, syntheseverfahren und diese derivate enthaltende medikamente - Google Patents

Chinolinderivate, syntheseverfahren und diese derivate enthaltende medikamente

Info

Publication number
DE60232186D1
DE60232186D1 DE60232186T DE60232186T DE60232186D1 DE 60232186 D1 DE60232186 D1 DE 60232186D1 DE 60232186 T DE60232186 T DE 60232186T DE 60232186 T DE60232186 T DE 60232186T DE 60232186 D1 DE60232186 D1 DE 60232186D1
Authority
DE
Germany
Prior art keywords
sub
derivatives
chinoline
synthesis methods
coor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60232186T
Other languages
German (de)
English (en)
Inventor
Angelo Jean D
Marie Bayle
Christophe Benard
Le Didier Desma
Michele Danet
Laurence Janson
Bret Marc Le
Herve Leh
Jean-Francois Mouscadet
Frederic Subra
Fatima Zouhiri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique
Institut Gustave Roussy
Institut National de la Santé et de la Recherche Médicale
Bioalliance Pharma SA
Université Paris-Sud
Original Assignee
Centre National de la Recherche Scientifique
Institut Gustave Roussy
Institut National de la Santé et de la Recherche Médicale
Bioalliance Pharma SA
Université Paris-Sud
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique, Institut Gustave Roussy, Institut National de la Santé et de la Recherche Médicale, Bioalliance Pharma SA, Université Paris-Sud filed Critical Centre National de la Recherche Scientifique
Application granted granted Critical
Publication of DE60232186D1 publication Critical patent/DE60232186D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60232186T 2001-10-12 2002-10-14 Chinolinderivate, syntheseverfahren und diese derivate enthaltende medikamente Expired - Lifetime DE60232186D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0113209A FR2830863B1 (fr) 2001-10-12 2001-10-12 Derives de quinoleine, procede de synthese, et medicaments renfermant ces derives
PCT/FR2002/003512 WO2003031413A1 (fr) 2001-10-12 2002-10-14 Derives de quinoleine, procede de synthese, et medicaments renfermant ces derives

Publications (1)

Publication Number Publication Date
DE60232186D1 true DE60232186D1 (de) 2009-06-10

Family

ID=8868255

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60232186T Expired - Lifetime DE60232186D1 (de) 2001-10-12 2002-10-14 Chinolinderivate, syntheseverfahren und diese derivate enthaltende medikamente

Country Status (10)

Country Link
US (2) US7064133B2 (enExample)
EP (1) EP1461319B1 (enExample)
JP (1) JP2005508350A (enExample)
AT (1) ATE430134T1 (enExample)
DE (1) DE60232186D1 (enExample)
DK (1) DK1461319T3 (enExample)
ES (1) ES2326115T3 (enExample)
FR (1) FR2830863B1 (enExample)
IL (2) IL161320A0 (enExample)
WO (1) WO2003031413A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2830863B1 (fr) * 2001-10-12 2004-01-30 Bioalliance Pharma Derives de quinoleine, procede de synthese, et medicaments renfermant ces derives
FR2839646B1 (fr) * 2002-05-17 2008-04-11 Bioalliance Pharma Utilisation de derives de quinoleine a effet anti-integrase et ses applications
US7132432B2 (en) * 2003-06-05 2006-11-07 Bristol-Myers Squibb Company Hydantoin derivatives as inhibitors of tumor necrosis factor-alpha converting enzyme (TACE)
TW200510425A (en) 2003-08-13 2005-03-16 Japan Tobacco Inc Nitrogen-containing fused ring compound and use thereof as HIV integrase inhibitor
ATE433974T1 (de) 2003-09-19 2009-07-15 Gilead Sciences Inc Azachinolinolphosphonatverbindungen als integraseinhibitoren
JP2008542352A (ja) * 2005-06-01 2008-11-27 ビオアリアンス ファルマ キノリン化合物及び他のｈｉｖ感染治療薬を含む相乗作用のコンビネーション

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2761687B1 (fr) * 1997-04-08 2000-09-15 Centre Nat Rech Scient Derives de quinoleines, possedant notamment des proprietes antivirales, leurs preparations et leurs applications biologiques
FR2830863B1 (fr) * 2001-10-12 2004-01-30 Bioalliance Pharma Derives de quinoleine, procede de synthese, et medicaments renfermant ces derives

Also Published As

Publication number Publication date
US20060148849A1 (en) 2006-07-06
FR2830863B1 (fr) 2004-01-30
EP1461319B1 (fr) 2009-04-29
WO2003031413A1 (fr) 2003-04-17
FR2830863A1 (fr) 2003-04-18
JP2005508350A (ja) 2005-03-31
DK1461319T3 (da) 2009-08-03
US7064133B2 (en) 2006-06-20
ATE430134T1 (de) 2009-05-15
US20040259911A1 (en) 2004-12-23
IL161320A0 (en) 2004-09-27
ES2326115T3 (es) 2009-10-01
IL161320A (en) 2009-09-01
EP1461319A1 (fr) 2004-09-29

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