IL161137A0 - Use of a formulation containing collagenase for degrading collagen in occluded arteries - Google Patents

Use of a formulation containing collagenase for degrading collagen in occluded arteries

Info

Publication number
IL161137A0
IL161137A0 IL16113702A IL16113702A IL161137A0 IL 161137 A0 IL161137 A0 IL 161137A0 IL 16113702 A IL16113702 A IL 16113702A IL 16113702 A IL16113702 A IL 16113702A IL 161137 A0 IL161137 A0 IL 161137A0
Authority
IL
Israel
Prior art keywords
formulation containing
containing collagenase
occluded arteries
degrading collagen
degrading
Prior art date
Application number
IL16113702A
Other languages
English (en)
Original Assignee
Bradley H Strauss
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bradley H Strauss filed Critical Bradley H Strauss
Publication of IL161137A0 publication Critical patent/IL161137A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4833—Thrombin (3.4.21.5)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/24003—Microbial collagenase (3.4.24.3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL16113702A 2001-10-01 2002-10-01 Use of a formulation containing collagenase for degrading collagen in occluded arteries IL161137A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32553901P 2001-10-01 2001-10-01
PCT/CA2002/001476 WO2003028756A2 (en) 2001-10-01 2002-10-01 An in vivo animal model of chronic arterial occlusion and use of collagenase to facilitate guide wire crossing in chronic arterial occlusions

Publications (1)

Publication Number Publication Date
IL161137A0 true IL161137A0 (en) 2004-08-31

Family

ID=23268311

Family Applications (2)

Application Number Title Priority Date Filing Date
IL16113702A IL161137A0 (en) 2001-10-01 2002-10-01 Use of a formulation containing collagenase for degrading collagen in occluded arteries
IL161137A IL161137A (en) 2001-10-01 2004-03-29 A drug that contains the enzyme collagenase for use in the treatment of chronic fibrotic complete obstruction

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL161137A IL161137A (en) 2001-10-01 2004-03-29 A drug that contains the enzyme collagenase for use in the treatment of chronic fibrotic complete obstruction

Country Status (13)

Country Link
US (3) US20050053548A1 (de)
EP (1) EP1438065B1 (de)
JP (1) JP2005503820A (de)
CN (1) CN1327893C (de)
AU (1) AU2002328729C1 (de)
CA (1) CA2462512C (de)
DK (1) DK1438065T3 (de)
ES (1) ES2396964T3 (de)
HK (1) HK1076037A1 (de)
IL (2) IL161137A0 (de)
PT (1) PT1438065E (de)
SI (1) SI1438065T1 (de)
WO (1) WO2003028756A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001245397A1 (en) * 2000-03-02 2001-09-12 Incyte Genomics, Inc. Lipid metabolism enzymes
US6569129B1 (en) * 2000-09-13 2003-05-27 Mayo Foundation For Medical Education And Research Biological revascularization
CN1327893C (zh) * 2001-10-01 2007-07-25 布雷德利 胶原酶在促进导线在完全动脉闭塞内通过中的应用
WO2005097177A1 (en) * 2004-04-08 2005-10-20 Strauss Bradley H Use of collagenase to facilitate guide wire crossing in total arterial occlusions
PL1827484T3 (pl) * 2004-12-02 2016-05-31 Matrizyme Pharma Corp Nasilenie tworzenia mikronaczyń wewnątrz światła naczynia w celu ułatwienia przeprowadzenia prowadnika przez przewlekłą całkowitą niedrożność
JP2007181413A (ja) * 2006-01-05 2007-07-19 Fujifilm Corp 血管壁障害モデル動物の作成方法
US20070184083A1 (en) * 2006-02-07 2007-08-09 Medtronic Vascular, Inc. Drug-Eluting Device for Treatment of Chronic Total Occlusions
US8541370B2 (en) 2007-02-26 2013-09-24 Proyecto De Biomedicina Cima, S.L. Use of matrix metalloproteinase-10 (MMP-10) for thrombolytic treatments
ES2335167B1 (es) * 2007-02-26 2011-01-24 Proyecto De Biomedicina Cima, S.L. Uso de la metaloproteinasa de matriz-10 (mmp10) para tratamientos tromboliticos.
US10071143B1 (en) 2007-05-03 2018-09-11 The Research Foundation For The State University Of New York Methods for non-surgical treatment of carpal tunnel syndrome
US8016799B2 (en) * 2008-04-22 2011-09-13 Medtronic Vascular, Inc. Catheter having a detachable tip
WO2011130537A2 (en) * 2010-04-14 2011-10-20 Northwestern University Pharmaceutical compositions and methods for digesting atherosclerotic plaques
US20120259314A1 (en) * 2011-04-11 2012-10-11 Medtronic Vascular, Inc. Apparatus and Methods for Recanalization of a Chronic Total Occlusion
CN103157099B (zh) * 2011-12-19 2015-03-18 吴宗贵 一种用于血管外膜快速消化的混合酶消液及其制备方法
US9636385B2 (en) 2012-10-24 2017-05-02 The Research Foundation For The State University Of New York Use of collagenase to treat glaucoma
US20160000834A1 (en) * 2013-02-28 2016-01-07 Ventrix, Inc. Methods and compositions for tissue therapy and analysis
CN103340663B (zh) * 2013-06-17 2016-05-04 李宝童 囊式冠脉压迫装置及慢性心肌缺血动物模型制造方法
WO2018109733A2 (en) * 2016-12-15 2018-06-21 Luseed Vascular Ltd. Methods and devices for treating vascular related disorders
US20220265291A9 (en) * 2018-06-28 2022-08-25 Marizyme, Inc. Pharmaceutical compositions and methods for the treatment of thrombosis and delivery by medical devices
AU2019292557A1 (en) * 2018-06-28 2021-04-01 Marizyme, Inc. Pharmaceutical compositions and methods for the treatment of thrombosis and delivery by medical devices

Family Cites Families (20)

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US4636195A (en) * 1982-04-02 1987-01-13 Harvey Wolinsky Method and apparatus for removing arterial constriction
US5811248A (en) 1986-03-31 1998-09-22 Charter Ventures Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof
US5955584A (en) * 1986-03-31 1999-09-21 Charter Ventures Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof
US6025477A (en) 1986-03-31 2000-02-15 Calenoff; Emanuel Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof
US5163421A (en) * 1988-01-22 1992-11-17 Angiosonics, Inc. In vivo ultrasonic system with angioplasty and ultrasonic contrast imaging
US5024829A (en) * 1988-11-21 1991-06-18 Centocor, Inc. Method of imaging coronary thrombi
US5328470A (en) 1989-03-31 1994-07-12 The Regents Of The University Of Michigan Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
DE69025934T2 (de) * 1989-05-17 1996-09-19 Res Corp Technologies Inc Verfahren und zusammensetzung zur thrombosebehandlung beim säugetier
US5422261A (en) * 1993-04-16 1995-06-06 Baxter International Inc. Composition containing collagenase and chymopapain for hydrolyzing connective tissue to isolate cells
US5613949A (en) * 1994-04-01 1997-03-25 Advanced Cardiovascular Systems, Inc. Double balloon catheter assembly
US5540637A (en) 1995-01-25 1996-07-30 Ccs, Llc Stationary exercise apparatus having a preferred foot platform orientation
US6020181A (en) 1995-05-17 2000-02-01 New York Blood, Inc. Inhibition of thrombus formation by medical related apparatus comprising treating with fibrinolytic matrix metalloproteinase
US6306166B1 (en) * 1997-08-13 2001-10-23 Scimed Life Systems, Inc. Loading and release of water-insoluble drugs
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EP1060747A3 (de) * 1999-06-16 2001-12-05 New York Blood Center, Inc. Fibrin-(fibrinogen-) Abbau und Gerinsel-Auflösung durch eine fibrinolytische Metallproteinase
US6569129B1 (en) * 2000-09-13 2003-05-27 Mayo Foundation For Medical Education And Research Biological revascularization
US6623452B2 (en) * 2000-12-19 2003-09-23 Scimed Life Systems, Inc. Drug delivery catheter having a highly compliant balloon with infusion holes
US6780849B2 (en) * 2000-12-21 2004-08-24 Scimed Life Systems, Inc. Lipid-based nitric oxide donors
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CN1327893C (zh) * 2001-10-01 2007-07-25 布雷德利 胶原酶在促进导线在完全动脉闭塞内通过中的应用

Also Published As

Publication number Publication date
CA2462512A1 (en) 2003-04-10
JP2005503820A (ja) 2005-02-10
WO2003028756A2 (en) 2003-04-10
IL161137A (en) 2014-08-31
AU2002328729A2 (en) 2003-04-14
US8021660B2 (en) 2011-09-20
PT1438065E (pt) 2013-01-24
CA2462512C (en) 2013-11-05
US7425326B2 (en) 2008-09-16
CN1599621A (zh) 2005-03-23
HK1076037A1 (en) 2006-01-06
US20090074744A1 (en) 2009-03-19
DK1438065T3 (da) 2013-02-11
EP1438065A2 (de) 2004-07-21
ES2396964T3 (es) 2013-03-01
AU2002328729C1 (en) 2009-11-26
SI1438065T1 (sl) 2013-03-29
WO2003028756A3 (en) 2003-08-28
EP1438065B1 (de) 2012-11-21
CN1327893C (zh) 2007-07-25
US20070014783A1 (en) 2007-01-18
AU2002328729B2 (en) 2009-07-16
US20050053548A1 (en) 2005-03-10

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