IL159535A0 - Use of poly-glu, tyr and t cells treated therewith for neuroprotection therapy - Google Patents
Use of poly-glu, tyr and t cells treated therewith for neuroprotection therapyInfo
- Publication number
- IL159535A0 IL159535A0 IL15953502A IL15953502A IL159535A0 IL 159535 A0 IL159535 A0 IL 159535A0 IL 15953502 A IL15953502 A IL 15953502A IL 15953502 A IL15953502 A IL 15953502A IL 159535 A0 IL159535 A0 IL 159535A0
- Authority
- IL
- Israel
- Prior art keywords
- tyr
- poly
- glu
- cells treated
- treated therewith
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title abstract 2
- 230000004112 neuroprotection Effects 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 210000003169 central nervous system Anatomy 0.000 abstract 3
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 2
- 210000001428 peripheral nervous system Anatomy 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000003292 glue Substances 0.000 abstract 1
- 229930195712 glutamate Natural products 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000005036 nerve Anatomy 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 230000008929 regeneration Effects 0.000 abstract 1
- 238000011069 regeneration method Methods 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/47—Brain; Nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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-
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- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
-
- A—HUMAN NECESSITIES
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- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/46432—Nervous system antigens
-
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/02—Nutrients, e.g. vitamins, minerals
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61P39/02—Antidotes
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Cell Biology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Biotechnology (AREA)
- Psychiatry (AREA)
- Oncology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Addiction (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/893,344 US6835711B2 (en) | 2001-06-28 | 2001-06-28 | Use of poly-Glu,Tyr for neuroprotective therapy |
PCT/IL2002/000517 WO2003002140A1 (fr) | 2001-06-28 | 2002-06-27 | Utilisation de poly-glu, tyr et cellules t traitees avec ceux-ci pour une therapie neuroprotectrice |
Publications (1)
Publication Number | Publication Date |
---|---|
IL159535A0 true IL159535A0 (en) | 2004-06-01 |
Family
ID=25401407
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15953502A IL159535A0 (en) | 2001-06-28 | 2002-06-27 | Use of poly-glu, tyr and t cells treated therewith for neuroprotection therapy |
Country Status (16)
Country | Link |
---|---|
US (1) | US6835711B2 (fr) |
EP (1) | EP1406650B1 (fr) |
JP (1) | JP4434729B2 (fr) |
KR (1) | KR20040032825A (fr) |
CN (1) | CN1326560C (fr) |
AT (1) | ATE412419T1 (fr) |
AU (1) | AU2002345323B2 (fr) |
CA (1) | CA2451521C (fr) |
DE (1) | DE60229639D1 (fr) |
DK (1) | DK1406650T3 (fr) |
ES (1) | ES2315371T3 (fr) |
HK (1) | HK1064951A1 (fr) |
IL (1) | IL159535A0 (fr) |
MX (1) | MXPA03011926A (fr) |
NZ (1) | NZ530261A (fr) |
WO (1) | WO2003002140A1 (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7399740B2 (en) * | 2001-06-28 | 2008-07-15 | Yeda Research And Development Co. Ltd. | Poly-Glu,Tyr for neuroprotective therapy |
WO2004060266A2 (fr) * | 2003-01-07 | 2004-07-22 | Yeda Research And Development Co. Ltd. | Vaccin sous forme de gouttes ophtalmiques contenant le copolymere poly-ye pour l'immunisation therapeutique |
SI1429800T1 (sl) * | 2001-12-06 | 2009-08-31 | Yeda Res & Dev | Cepivo in njegova uporaba za zdravljenje amiotrofiäśne lateralne skleroze |
CN1835679A (zh) * | 2003-06-16 | 2006-09-20 | 国立大学法人九州大学 | 人源免疫活性细胞的制备方法 |
US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
JP4808631B2 (ja) * | 2003-12-09 | 2011-11-02 | イエダ リサーチ アンド デベロップメント カンパニー リミテッド | 精神医学的障害の治療用のコポリマー1を含む方法及びワクチン |
WO2005055920A2 (fr) * | 2003-12-09 | 2005-06-23 | Yeda Research And Development Co. Ltd. | Compositions et methodes de traitement de troubles psychiatriques |
JP5294635B2 (ja) * | 2004-11-29 | 2013-09-18 | イエダ リサーチ アンド デベロップメント カンパニー リミテッド | コポリマー1と組み合わせた、神経発生の誘発及び幹細胞治療 |
US9220813B2 (en) * | 2005-04-18 | 2015-12-29 | Holy Cross Hospital, Inc. | Cell therapy for limiting overzealous inflammatory reactions in tissue healing |
EP2234633A1 (fr) * | 2007-12-21 | 2010-10-06 | Ben Gurion University Of The Negev Research And Development Authority | Procédé de traitement de maladies neurodégénératives |
EP2349028A1 (fr) * | 2008-04-04 | 2011-08-03 | The Cleveland Clinic Foundation | Utilisation de greffons de gaine épineurale pour régénération et protection neurale |
EP2379087B1 (fr) * | 2008-12-19 | 2014-08-20 | DePuy Synthes Products, LLC | Cellules extraites du tissu du cordon ombilical pour le traitement de douleur neuropathique et de la spasticité |
US8722034B2 (en) | 2009-03-26 | 2014-05-13 | Depuy Synthes Products Llc | hUTC as therapy for Alzheimer's disease |
WO2011028814A1 (fr) * | 2009-09-04 | 2011-03-10 | The Cleveland Clinic Foundation | Procédés d'ingénierie de tissu neural |
CN107661490B (zh) | 2010-01-04 | 2021-12-31 | Mapi医药公司 | 包含格拉默或其药用盐的储药系统 |
USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
US8377885B2 (en) | 2010-01-04 | 2013-02-19 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
ES2601892T3 (es) | 2011-04-21 | 2017-02-16 | Mapi Pharma Limited | Pentapolímero aleatorio para el tratamiento de enfermedades autoinmunes |
WO2018178973A1 (fr) | 2017-03-26 | 2018-10-04 | Mapi Pharma Ltd. | Systèmes de dépôt de glatiramère pour le traitement de formes progressives de sclérose en plaques |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999034827A1 (fr) | 1998-07-21 | 1999-07-15 | Yeda Research And Development Co. Ltd. | Lymphocytes actives et leurs utilisations |
-
2001
- 2001-06-28 US US09/893,344 patent/US6835711B2/en not_active Expired - Fee Related
-
2002
- 2002-06-27 CA CA2451521A patent/CA2451521C/fr not_active Expired - Fee Related
- 2002-06-27 JP JP2003508379A patent/JP4434729B2/ja not_active Expired - Fee Related
- 2002-06-27 MX MXPA03011926A patent/MXPA03011926A/es active IP Right Grant
- 2002-06-27 WO PCT/IL2002/000517 patent/WO2003002140A1/fr active Application Filing
- 2002-06-27 KR KR10-2003-7016949A patent/KR20040032825A/ko not_active Application Discontinuation
- 2002-06-27 DE DE60229639T patent/DE60229639D1/de not_active Expired - Lifetime
- 2002-06-27 AU AU2002345323A patent/AU2002345323B2/en not_active Ceased
- 2002-06-27 CN CNB028165462A patent/CN1326560C/zh not_active Expired - Fee Related
- 2002-06-27 ES ES02743592T patent/ES2315371T3/es not_active Expired - Lifetime
- 2002-06-27 IL IL15953502A patent/IL159535A0/xx unknown
- 2002-06-27 AT AT02743592T patent/ATE412419T1/de not_active IP Right Cessation
- 2002-06-27 DK DK02743592T patent/DK1406650T3/da active
- 2002-06-27 EP EP02743592A patent/EP1406650B1/fr not_active Expired - Lifetime
- 2002-06-27 NZ NZ530261A patent/NZ530261A/en not_active IP Right Cessation
-
2004
- 2004-10-12 HK HK04107851.9A patent/HK1064951A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP2005502616A (ja) | 2005-01-27 |
AU2002345323B2 (en) | 2006-12-21 |
CN1547482A (zh) | 2004-11-17 |
CA2451521C (fr) | 2011-05-17 |
DK1406650T3 (da) | 2009-03-02 |
ES2315371T3 (es) | 2009-04-01 |
CN1326560C (zh) | 2007-07-18 |
WO2003002140A1 (fr) | 2003-01-09 |
EP1406650B1 (fr) | 2008-10-29 |
US20030003082A1 (en) | 2003-01-02 |
KR20040032825A (ko) | 2004-04-17 |
US6835711B2 (en) | 2004-12-28 |
DE60229639D1 (de) | 2008-12-11 |
HK1064951A1 (en) | 2005-02-08 |
MXPA03011926A (es) | 2004-03-26 |
ATE412419T1 (de) | 2008-11-15 |
NZ530261A (en) | 2006-06-30 |
CA2451521A1 (fr) | 2003-01-09 |
JP4434729B2 (ja) | 2010-03-17 |
EP1406650A1 (fr) | 2004-04-14 |
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