IL158249A0 - New process for the preparation of oxabispodines - Google Patents
New process for the preparation of oxabispodinesInfo
- Publication number
- IL158249A0 IL158249A0 IL15824902A IL15824902A IL158249A0 IL 158249 A0 IL158249 A0 IL 158249A0 IL 15824902 A IL15824902 A IL 15824902A IL 15824902 A IL15824902 A IL 15824902A IL 158249 A0 IL158249 A0 IL 158249A0
- Authority
- IL
- Israel
- Prior art keywords
- sup
- formula
- compound
- preparation
- oxabispodines
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 abstract 1
- 239000012948 isocyanate Substances 0.000 abstract 1
- 150000002513 isocyanates Chemical class 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 230000008707 rearrangement Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0101324A SE0101324D0 (sv) | 2001-04-12 | 2001-04-12 | New process |
| PCT/SE2002/000727 WO2002083690A1 (en) | 2001-04-12 | 2002-04-12 | New process for the preparation of oxabispidines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL158249A0 true IL158249A0 (en) | 2004-05-12 |
Family
ID=20283781
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15824902A IL158249A0 (en) | 2001-04-12 | 2002-04-12 | New process for the preparation of oxabispodines |
| IL158249A IL158249A (en) | 2001-04-12 | 2003-10-02 | Process for the preparation of oxabispidines |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL158249A IL158249A (en) | 2001-04-12 | 2003-10-02 | Process for the preparation of oxabispidines |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US7169921B2 (es) |
| EP (1) | EP1385850B1 (es) |
| JP (1) | JP4248880B2 (es) |
| KR (1) | KR100848613B1 (es) |
| CN (1) | CN1267435C (es) |
| AT (1) | ATE284405T1 (es) |
| AU (1) | AU2002249748B2 (es) |
| BR (1) | BR0208861A (es) |
| CA (1) | CA2443475A1 (es) |
| DE (1) | DE60202203T2 (es) |
| ES (1) | ES2233809T3 (es) |
| IL (2) | IL158249A0 (es) |
| MX (1) | MXPA03009211A (es) |
| NO (1) | NO20034526L (es) |
| NZ (1) | NZ528515A (es) |
| PT (1) | PT1385850E (es) |
| SE (1) | SE0101324D0 (es) |
| WO (1) | WO2002083690A1 (es) |
| ZA (1) | ZA200307676B (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0101324D0 (sv) * | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | New process |
| GB0223712D0 (en) | 2002-10-14 | 2002-11-20 | Astrazeneca Ab | Chemical intermediate |
| US20040192738A1 (en) * | 2003-03-18 | 2004-09-30 | Aventis Pharma Deutschland Gmbh | 2-(Butyl-1-sulfonylamino)-N-[1(R)-(6-methoxypyridin-3-yl)propyl] benzamide, its use as a medicament, and pharmaceutical preparations comprising it |
| SE0401540D0 (sv) * | 2004-06-15 | 2004-06-15 | Astrazeneca Ab | New compounds |
| SE0401539D0 (sv) | 2004-06-15 | 2004-06-15 | Astrazeneca Ab | New compounds |
| JP2008543750A (ja) * | 2005-06-13 | 2008-12-04 | アストラゼネカ アクチボラグ | 心不整脈の処置用の新規オキサビスピジン化合物 |
| CN101198600A (zh) * | 2005-06-16 | 2008-06-11 | 集润德斯股份公司 | 氢醌衍生物的合成 |
| US20100222335A1 (en) * | 2005-06-20 | 2010-09-02 | Astrazeneca Ab | Process For The Preparation Of N,N'-Disubstituted Oxabispidines |
| WO2006137772A1 (en) * | 2005-06-20 | 2006-12-28 | Astrazeneca Ab | New physical form of n,n´- disubstituted oxabispidines |
| MX2007016093A (es) * | 2005-06-20 | 2008-03-10 | Astrazeneca Ab | Proceso para la produccion de sulfonatos de (alcoxicarbonilamino)- alquilo. |
| CA2610093A1 (en) * | 2005-06-20 | 2006-12-28 | Astrazeneca Ab | Process for the preparation of sulfonic acid salts of oxabispidines |
| WO2006137773A1 (en) * | 2005-06-20 | 2006-12-28 | Astrazeneca Ab | Process for the isolation of 4-(oxiranylmethoxy)-benzonitriles |
| AR054391A1 (es) * | 2005-06-20 | 2007-06-20 | Astrazeneca Ab | Procedimiento para la preparacion de 3,7- dihidroxi-1,5-diazaciclooctanos |
| SG10201802911RA (en) | 2013-03-15 | 2018-05-30 | Global Blood Therapeutics Inc | Compounds and uses thereof for the modulation of hemoglobin |
| EA202092627A1 (ru) | 2013-11-18 | 2021-09-30 | Глобал Блад Терапьютикс, Инк. | Соединения и их применения для модуляции гемоглобина |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3196154A (en) | 1962-05-17 | 1965-07-20 | Sterling Drug Inc | 3-substituted-9-methyl-3, 9-diazabicyclo [3.3.1] nonanes |
| US5110933A (en) * | 1989-11-13 | 1992-05-05 | Board Of Regents Of Oklahoma State University | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof |
| SE9704709D0 (sv) * | 1997-12-17 | 1997-12-17 | Astra Ab | Pharmaceutically active compounds |
| SE9903759D0 (sv) * | 1999-10-18 | 1999-10-18 | Astra Ab | Pharmaceutically active compounds |
| SE0101324D0 (sv) * | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | New process |
-
2001
- 2001-04-12 SE SE0101324A patent/SE0101324D0/xx unknown
-
2002
- 2002-04-12 MX MXPA03009211A patent/MXPA03009211A/es active IP Right Grant
- 2002-04-12 CA CA002443475A patent/CA2443475A1/en not_active Abandoned
- 2002-04-12 AU AU2002249748A patent/AU2002249748B2/en not_active Ceased
- 2002-04-12 US US10/474,593 patent/US7169921B2/en not_active Expired - Fee Related
- 2002-04-12 IL IL15824902A patent/IL158249A0/xx unknown
- 2002-04-12 EP EP02718766A patent/EP1385850B1/en not_active Expired - Lifetime
- 2002-04-12 KR KR1020037013158A patent/KR100848613B1/ko not_active Expired - Fee Related
- 2002-04-12 ES ES02718766T patent/ES2233809T3/es not_active Expired - Lifetime
- 2002-04-12 JP JP2002581445A patent/JP4248880B2/ja not_active Expired - Fee Related
- 2002-04-12 DE DE60202203T patent/DE60202203T2/de not_active Expired - Lifetime
- 2002-04-12 WO PCT/SE2002/000727 patent/WO2002083690A1/en not_active Ceased
- 2002-04-12 AT AT02718766T patent/ATE284405T1/de not_active IP Right Cessation
- 2002-04-12 CN CNB028115759A patent/CN1267435C/zh not_active Expired - Fee Related
- 2002-04-12 BR BR0208861-4A patent/BR0208861A/pt not_active IP Right Cessation
- 2002-04-12 NZ NZ528515A patent/NZ528515A/en unknown
- 2002-04-12 PT PT02718766T patent/PT1385850E/pt unknown
-
2003
- 2003-10-01 ZA ZA200307676A patent/ZA200307676B/en unknown
- 2003-10-02 IL IL158249A patent/IL158249A/en not_active IP Right Cessation
- 2003-10-09 NO NO20034526A patent/NO20034526L/no not_active Application Discontinuation
-
2006
- 2006-12-19 US US11/612,826 patent/US20070197519A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US7169921B2 (en) | 2007-01-30 |
| MXPA03009211A (es) | 2004-01-29 |
| SE0101324D0 (sv) | 2001-04-12 |
| ATE284405T1 (de) | 2004-12-15 |
| KR100848613B1 (ko) | 2008-07-28 |
| KR20030087065A (ko) | 2003-11-12 |
| PT1385850E (pt) | 2005-03-31 |
| WO2002083690A1 (en) | 2002-10-24 |
| HK1060886A1 (en) | 2004-08-27 |
| JP4248880B2 (ja) | 2009-04-02 |
| DE60202203T2 (de) | 2005-12-15 |
| US20040181060A1 (en) | 2004-09-16 |
| AU2002249748B2 (en) | 2008-02-28 |
| CA2443475A1 (en) | 2002-10-24 |
| DE60202203D1 (de) | 2005-01-13 |
| NO20034526D0 (no) | 2003-10-09 |
| EP1385850B1 (en) | 2004-12-08 |
| NO20034526L (no) | 2003-10-31 |
| ZA200307676B (en) | 2004-07-13 |
| BR0208861A (pt) | 2004-10-19 |
| IL158249A (en) | 2009-09-01 |
| ES2233809T3 (es) | 2005-06-16 |
| US20070197519A1 (en) | 2007-08-23 |
| NZ528515A (en) | 2005-06-24 |
| JP2004533432A (ja) | 2004-11-04 |
| CN1520417A (zh) | 2004-08-11 |
| CN1267435C (zh) | 2006-08-02 |
| EP1385850A1 (en) | 2004-02-04 |
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