IL157540A0 - N-(aryl)-2-arylethenesulphonamides and therapeutic uses thereof - Google Patents
N-(aryl)-2-arylethenesulphonamides and therapeutic uses thereofInfo
- Publication number
- IL157540A0 IL157540A0 IL15754002A IL15754002A IL157540A0 IL 157540 A0 IL157540 A0 IL 157540A0 IL 15754002 A IL15754002 A IL 15754002A IL 15754002 A IL15754002 A IL 15754002A IL 157540 A0 IL157540 A0 IL 157540A0
- Authority
- IL
- Israel
- Prior art keywords
- aryl
- arylethenesulphonamides
- therapeutic uses
- agents
- useful
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- 230000001028 anti-proliverative effect Effects 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- -1 for example Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000718 radiation-protective agent Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
- C07C311/39—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/12—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
- C07C311/13—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/23—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
- C07C311/27—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Quinoline Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Indole Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27198501P | 2001-02-28 | 2001-02-28 | |
| PCT/US2002/005979 WO2002067865A2 (en) | 2001-02-28 | 2002-02-28 | N-(aryl)-2-arylethenesulfonamides and therapeutic uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL157540A0 true IL157540A0 (en) | 2004-03-28 |
Family
ID=23037924
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15754002A IL157540A0 (en) | 2001-02-28 | 2002-02-28 | N-(aryl)-2-arylethenesulphonamides and therapeutic uses thereof |
| IL157540A IL157540A (en) | 2001-02-28 | 2003-08-21 | Pharmaceutical compositions comprising n-(aryl)-2-arylethenesulfonamides, some such novel compounds and process for their preparation |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL157540A IL157540A (en) | 2001-02-28 | 2003-08-21 | Pharmaceutical compositions comprising n-(aryl)-2-arylethenesulfonamides, some such novel compounds and process for their preparation |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6646009B2 (enExample) |
| EP (1) | EP1379508B9 (enExample) |
| JP (1) | JP4171656B2 (enExample) |
| KR (1) | KR100850330B1 (enExample) |
| AT (1) | ATE479657T1 (enExample) |
| AU (1) | AU2002306604B2 (enExample) |
| CA (1) | CA2439255C (enExample) |
| DE (1) | DE60237512D1 (enExample) |
| DK (1) | DK1379508T3 (enExample) |
| IL (2) | IL157540A0 (enExample) |
| WO (1) | WO2002067865A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4302986B2 (ja) * | 2001-02-28 | 2009-07-29 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | 細胞及び組織をα，β不飽和アリールスルホンにより電離放射線から防護する方法 |
| MXPA04008356A (es) * | 2002-02-28 | 2005-09-12 | Univ Temple | (e)-2,6-dialcoxiestiril bencilsulfonas sustituidas con un grupo amino y en la posicion 4 para tratar trastornos poliferativos. |
| US7161031B2 (en) * | 2002-02-28 | 2007-01-09 | Temple University - Of The Commonwealth System Of Higher Education | Amino-substituted sulfonanilides and derivatives thereof for treating proliferative disorders |
| HUE032523T2 (en) * | 2003-11-14 | 2017-09-28 | Temple Univ - Of The Commonwealth System Of Higher Education | Alpha, beta-unsaturated sulfoxides for the treatment of proliferative disorders |
| EP1740530B8 (en) | 2004-03-16 | 2017-03-01 | Temple University - Of The Commonwealth System of Higher Education | Substituted phenoxy- and phenylthio-derivatives for treating proliferative disorders |
| WO2005090297A1 (en) * | 2004-03-19 | 2005-09-29 | Biotie Therapies Corporation | Sulphonamide derivatives |
| MX352516B (es) * | 2006-07-05 | 2017-04-06 | Fibrotech Therapeutics Pty Ltd | Compuestos terapeuticos. |
| JP5278968B2 (ja) | 2006-08-30 | 2013-09-04 | テンプル・ユニバーシティ−オブ・ザ・コモンウェルス・システム・オブ・ハイアー・エデュケイション | 骨髄異形性症候群及び急性骨髄性白血病の治療のための組成物及び方法 |
| CA2709937C (en) * | 2007-12-21 | 2016-03-22 | Fibrotech Therapeutics Pty Ltd | Halogenated analogues of anti-fibrotic agents |
| WO2010144959A1 (en) * | 2009-06-18 | 2010-12-23 | Fibrotech Therapeutics Pty Ltd | Analogues of anti-fibrotic agents |
| EP2947073B1 (en) | 2009-10-22 | 2019-04-03 | Fibrotech Therapeutics Pty Ltd | Fused ring analogues of anti-fibrotic agents |
| WO2013039985A2 (en) * | 2011-09-12 | 2013-03-21 | The Johns Hopkins University | Serine protease inhibitors |
| US9730913B2 (en) | 2011-10-13 | 2017-08-15 | The Johns Hopkins University | High affinity beta lactamase inhibitors |
| ES2863538T3 (es) | 2012-09-20 | 2021-10-11 | Univ Temple | Derivados de alquil diarilo sustituidos, métodos de preparación y usos |
| US10383831B2 (en) | 2015-08-03 | 2019-08-20 | Temple University—Of the Commonwealth System of Higher Education | 2,4,6-trialkoxystryl aryl sulfones, sulfonamides and carboxamides, and methods of preparation and use |
| SG11201907139UA (en) | 2017-02-03 | 2019-09-27 | Certa Therapeutics Pty Ltd | Anti-fibrotic compounds |
| WO2020150439A1 (en) * | 2019-01-17 | 2020-07-23 | Ifm Due, Inc. | Compounds and compositions for treating conditions associated with sting activity |
| PY2269135A (es) | 2021-08-10 | 2024-01-29 | Ifm Due Inc | Compuestos y composiciones para tratar afecciones asociadas con la actividad de sting |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2531367A (en) * | 1947-07-15 | 1950-11-21 | Sharp & Dohme Inc | N-(substituted sulfonyl)-aminobenzoic acids |
| DE2118493C3 (de) | 1971-04-16 | 1980-04-30 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung von Aminostilbenen |
| US4035421A (en) | 1976-03-19 | 1977-07-12 | Morton-Norwich Products, Inc. | N-(3,4,-dichlorophenyl)-2-phenylethenesulfonamide |
| DE2809377A1 (de) * | 1978-03-04 | 1979-09-13 | Boehringer Mannheim Gmbh | Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| ZA915371B (en) | 1990-07-17 | 1993-03-31 | Lilly Co Eli | Antitumor compositions and methods of treatment |
| JPH04202173A (ja) * | 1990-11-30 | 1992-07-22 | Zeria Pharmaceut Co Ltd | スルホンアミド誘導体及びそれを含有する５―リポキシゲナーゼ阻害剤 |
| WO1995024190A2 (en) * | 1994-03-07 | 1995-09-14 | Sugen, Inc. | Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof |
| EP0809492A4 (en) | 1995-02-17 | 2007-01-24 | Smithkline Beecham Corp | IL-8 RECEPTOR ANTAGONISTS |
| US5780483A (en) * | 1995-02-17 | 1998-07-14 | Smithkline Beecham Corporation | IL-8 receptor antagonists |
| CA2244785C (en) | 1996-02-22 | 2003-12-02 | Tularik, Inc. | Pentafluorobenzenesulfonamides and analogs |
| US6191170B1 (en) * | 1998-01-13 | 2001-02-20 | Tularik Inc. | Benzenesulfonamides and benzamides as therapeutic agents |
| KR100642184B1 (ko) | 1998-09-23 | 2006-11-10 | 암젠 인크 | 아릴술폰아닐리드 우레아 |
| US6586617B1 (en) * | 1999-04-28 | 2003-07-01 | Sumitomo Chemical Takeda Agro Company, Limited | Sulfonamide derivatives |
-
2002
- 2002-02-28 JP JP2002567237A patent/JP4171656B2/ja not_active Expired - Fee Related
- 2002-02-28 DK DK02802229.1T patent/DK1379508T3/da active
- 2002-02-28 DE DE60237512T patent/DE60237512D1/de not_active Expired - Lifetime
- 2002-02-28 CA CA2439255A patent/CA2439255C/en not_active Expired - Fee Related
- 2002-02-28 KR KR1020037011303A patent/KR100850330B1/ko not_active Expired - Fee Related
- 2002-02-28 AU AU2002306604A patent/AU2002306604B2/en not_active Ceased
- 2002-02-28 IL IL15754002A patent/IL157540A0/xx unknown
- 2002-02-28 US US10/085,826 patent/US6646009B2/en not_active Expired - Lifetime
- 2002-02-28 WO PCT/US2002/005979 patent/WO2002067865A2/en not_active Ceased
- 2002-02-28 EP EP02802229A patent/EP1379508B9/en not_active Expired - Lifetime
- 2002-02-28 AT AT02802229T patent/ATE479657T1/de not_active IP Right Cessation
-
2003
- 2003-08-21 IL IL157540A patent/IL157540A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL157540A (en) | 2010-11-30 |
| KR20030086279A (ko) | 2003-11-07 |
| US6646009B2 (en) | 2003-11-11 |
| CA2439255C (en) | 2011-01-04 |
| JP4171656B2 (ja) | 2008-10-22 |
| AU2002306604B2 (en) | 2007-09-13 |
| CA2439255A1 (en) | 2002-09-06 |
| EP1379508A4 (en) | 2005-12-28 |
| EP1379508B1 (en) | 2010-09-01 |
| KR100850330B1 (ko) | 2008-08-04 |
| WO2002067865A3 (en) | 2003-03-20 |
| EP1379508B9 (en) | 2011-02-09 |
| EP1379508A2 (en) | 2004-01-14 |
| JP2004530655A (ja) | 2004-10-07 |
| US20020165412A1 (en) | 2002-11-07 |
| ATE479657T1 (de) | 2010-09-15 |
| WO2002067865A2 (en) | 2002-09-06 |
| DE60237512D1 (de) | 2010-10-14 |
| DK1379508T3 (da) | 2011-01-03 |
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